Khachik, K.     Rejuvenation: the calm before the storm [Text] / K. Khachik, Vadim E. Fraifeld // Журнал неврології ім. Б.М. Маньковського. - 2021. - N 3. - P31-32 MeSH-головна: ОМОЛОЖЕНИЕ -- REJUVENATION (физиология) МЕДИЦИНА РЕГЕНЕРАТИВНАЯ -- REGENERATIVE MEDICINE (методы) ИССЛЕДОВАТЕЛЬСКИЕ ТЕХНОЛОГИИ (ВНЕШ) -- INVESTIGATIVE TECHNIQUES (NON MESH) Анотація: Since ancient civilizations, controlling aging and rejuvenation has been a cherished human aspiration. Centuries and millennia have passed. Yet, we keep asking the same questions. Why and how do we get older? What can be done to stop or reverse aging? The very existence of quasi-immortal species in the kingdoms of animals, plants and fungi (jellyfish, hydra, corals, sponges, sea anemones, filamentous fungi, etc.) leaves little doubt that longevity and rejuvenation can be manipulated. Moreover, the very existence of life proves that rejuvenation is its inherent feature. Evolutionary well-designed mechanisms of rejuvenation (gametogenesis, embryonic development, resetting the aging clock, soma-to-germ cell transformation, asymmetric partition, etc.) can be relevant models to comprehend driving forces of rejuvenation. In favor of rejuvenation feasibility are also breakthrough discoveries in cellular reprogramming and induced pluripotency, supporting the fundamental fact — somatic cells, like the reproductive ones, have unlimited replicative potential (URP) Дод.точки доступу: Fraifeld, Vadim E. Вільних прим. немає