Bolonska, A. V. Treatment and prophylaxis of moderate and severe bronchopulmonary dysplasia in premature neonates [Text] / A. V. Bolonska, O. Yu. Sorokina> // Медичні перспективи. - 2021. - Т. 26, № 3WМУ10/2021/26/3. - P84-93. - Bibliogr. at the end of the art. MeSH-головна: БРОНХОЛЕГОЧНАЯ ДИСПЛАЗИЯ -- BRONCHOPULMONARY DYSPLASIA (диагностика, лекарственная терапия, профилактика и контроль, реабилитация, терапия) МЛАДЕНЕЦ НЕДОНОШЕННЫЙ, БОЛЕЗНИ -- INFANT, PREMATURE, DISEASES (диагностика, лекарственная терапия, профилактика и контроль, реабилитация, терапия) ЛЕГКИХ ВЕНТИЛЯЦИЯ -- PULMONARY VENTILATION (действие лекарственных препаратов, физиология) ИНТЕНСИВНАЯ ТЕРАПИЯ НОВОРОЖДЕННЫХ -- INTENSIVE CARE, NEONATAL (использование, методы) Анотація: Bronchopulmonary dysplasia in premature neonates leads to physical and mental developmental disorders and behavioral problems and associated with frequent rehospitalizations and long hospital stay. Study objective: to study the predictors of bronchopulmonary dysplasia development in premature neonates in structure of intensive care. Study design: A retrospective cohort analysis was performed in 127 children recruited from two NICU of Dnipro between January 2016 to March 2020. Inclusion criteria: preterm neonates 28-32 gestation weeks with respiratory distress syndrome (RDS). Results demonstrated that every day of mechanical ventilation, supplemental oxygen with FiO2 more than 30% and cardiac drugs usage increased risk of bronchopulmonary dysplasia development by 15-20%. In conclusion, finding out predictors of bronchopulmonary dysplasia helps to improve and prudently use usual treatment regimens in premature neonates and decrease the frequency of moderate and severe bronchopulmonary dysplasia Дод.точки доступу: Sorokina, O. Yu. |