Expression pattern of MRPS 18 family genes in gliomas / L. M. Kovalevska [et al.]> // Experimental Oncology. - 2021. - Том 43, N 3. - P204-208
MeSH-головна: ГЕННАЯ ЭКСПРЕССИЯ -- GENE EXPRESSION ГЛИОМА -- GLIOMA (генетика, диагностика) ГЛИОБЛАСТОМА -- GLIOBLASTOMA (генетика, диагностика) БИОЛОГИЯ КОМПЬЮТЕРНАЯ -- COMPUTATIONAL BIOLOGY (методы) Анотація: To assess expression patterns of MRPS18 family genes in glioblastoma tissues and glioma cell lines. Materials and Methods: Expression of MRPS18 family genes was analyzed by quantitative polymerase chain reaction in glioma cell lines and glioblastoma specimens. A bioinformatic analysis of the publicly available data on the expression of these genes was also provided. Results: The genes of MRPS18 family show different expression patterns in glioblastomas and glioma cell lines. The highest levels of expression were found for MRPS18-2 at mRNA and protein levels in both glioblastomas and glioma cell lines; the lowest — for MRPS18-1 at mRNA level. Conclusions: The elevated levels of relative expression of the MRPS18-2 gene are characteristic for glioma tumor tissues and cell lines Дод.точки доступу: Kovalevska, L. M. Malysheva, T. A. Kalman, S. S. Rozumenko, A. V. Verbova, L. V. Rozumenko, V. D. Kashuba, E. V.
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