Analysing association between anthropometric indicators of insulin resistance and insulin-like growth factor-1 in patients with nodular goiter / O. S. Miroshnichenko [et al.] // Пробл. ендокринної патології. - 2021. - N 4. - P40-49 MeSH-головна: ЗОБ УЗЛОВОЙ -- GOITER, NODULAR (патофизиология, этиология) ИНСУЛИНОРЕЗИСТЕНТНОСТЬ -- INSULIN RESISTANCE МЕТАБОЛИЧЕСКИЙ СИНДРОМ X -- METABOLIC SYNDROME X Анотація: Publications suggesting that thyroid nodule might be associated with insulin resistance (IR) and metabolic syndrome are quite interesting. In a very recent report, increased thyroid volume and nodule prevalence were also reported in patients with IR in an iodine-sufficient area []. The purpose of the work is to analyze the association between anthropometric indicators IR and IGF-1 in patients with nodular goiter Patients with nodular goiter with IGF-1 level in blood above the sex-age norm have significantly higher values ​​of anthropometric indicators IR (WHtR, ABSI, BFD and BAI) compared with patients with a normal level of this indicator; in patients with nodular goiter with II degree obesity and above, thyroid volume is significantly associated with BMI; BAI (R2 = 82.37%) is a predictor of increased levels of IGF-1 in blood of patients with nodular goiter, regardless of the obesity; BRI (R2 = 81.14%) is a predictor of increased thyroid volume in patients with nodular goiter with IGF -1 high level and obesity Дод.точки доступу: Miroshnichenko, O. S. Mykytyuk, M. R. Cherniavska, I. V. Dubovyk, V. M. Seliukova, N. Yu. Dorosh, O. G. Gerasymenko, V. L. Sazonov, M. Ye. Вільних прим. немає