Форма документа : Стаття із журналу Шифр видання : Автор(и) : Myhal A. V., Marksa M. , Golovchenko O. S., Georgiyants V. A., Ivanauskas L. Назва : Comparison of chromatographic methods of analysis in a thin layer of the sorbent for identification of famotidine in tablets Місце публікування : Вісн. фармації. - Х., 2017. - № 2. - С. 21-24 (Шифр ВУ18/2017/2) MeSH-головна: ФАМОТИДИН -- FAMOTIDINE ТАБЛЕТКИ -- TABLETS ХРОМАТОГРАФИЯ ТОНКОСЛОЙНАЯ -- CHROMATOGRAPHY, THIN LAYER Анотація: Today three national manufacturers produce famotidine tablets, but the SPhU does not contain any monograph for this dosage form. Aim. To verify TLC and study the possibility of using the HPTLC method for identification of famotidine in tablets. Materials and methods. The objects of the study were three batches of famotidine tablets. TLC and HPTLC were used as the methods of the study. Results and discussion. The possibility of using TLC and HPTLC methods for identification of famotidine tablets was confirmed in the study. The main spots of the test solutions corresponded to the size and the Rf value of the main spots of the standard solution. The Rf value for all solutions was 0.5. Conclusions. Thus, TLC as well as HPTLC can be recommended for inclusion to the SPhU; however, HPTLC is more economically advantageous Дод.точки доступу: Myhal, A. V. Marksa, M. Golovchenko, O. S. Georgiyants, V. A. Ivanauskas, L. |