Форма документа : Стаття із журналу Шифр видання : Автор(и) : Suleimanova R. R., Hudz E. A., Melnychuk D. O., Kalachniuk L. H. Назва : Age-related changes of phospholipids in sterlet liver and dorsal muscles Місце публікування : The Ukrainian Biochemical Journal. - Київ, 2017. - Том 89, N 1. - С. 71-75 (Шифр УУ1/2017/89/1) MeSH-головна: НЕАЛКОГОЛЬНАЯ ЖИРОВАЯ БОЛЕЗНЬ ПЕЧЕНИ -- NON-ALCOHOLIC FATTY LIVER DISEASE СПИННЫЕ МЫШЦЫ -- BACK MUSCLES ФОСФОЛИПИДЫ -- PHOSPHOLIPIDS РЫБЫ -- FISHES Анотація: Study of phospholipids changes peculiarities in the liver and dorsal muscles of sterlet (Acipenser ruthenus Linnaeus) may be important to determine the etiology and pathogenesis of fatty liver. We established that the content of total phospholipids in tissues of the liver and dorsal muscles of three-year-old sterlet was less than for two-year-old fish by 15% and 20% (P ≤ 0.01), respectively. The amount of phosphatidylcholine (P ≤ 0.05), phosphatidylethanolamine, phosphatidylserine (P ≤ 0.01), phosphatidylinositol (P ≤ 0.01) and cardiolipin in the liver of 3-year-old sterlet was lower than for the 2-year-old fish, while quantitative indices for lysophosphatidylcholine and sphingomyelin were slightly increased. Similarly, in the cells of the dorsal muscles, the amount of phospholipid components (except lysophosphatidylcholine) was decreased with age. A decrease in the amount of phosphatidylethanolamine and phosphatidylserine in the dorsal muscles of 3-year-old sterlet was significant. The major phospholipids respective distribution was stable, except for phosphatidylethanolamine and particularly sphingomyelin Дод.точки доступу: Suleimanova, R. R. Hudz, E. A. Melnychuk, D. O. Kalachniuk, L. H.