Форма документа : Стаття із журналу
Шифр видання :
Автор(и) : Vavrinevych O. P., Shpak B. I., Antonenko A. M., Omelchuk S. T., Zinchenko T. I.
Назва : Hygienic substantiation of calculating models for prognosis of toxicity of different classes insecticides (second part)
Місце публікування : Медичні перспективи. - Д., 2020. - Т. 25, № 4. - С. 166-173 (Шифр МУ10/2020/25/4)
Примітки : Bibliogr. at the end of the art.
MeSH-головна: ИНСЕКТИЦИДЫ -- INSECTICIDES
МОДЕЛИ СТАТИСТИЧЕСКИЕ -- MODELS, STATISTICAL
ТОКСИКОЛОГИЯ -- TOXICOLOGY
ОКРУЖАЮЩЕЙ СРЕДЫ ГИГИЕНА -- ENVIRONMENTAL MEDICINE
ПРОГНОЗ -- PROGNOSIS
Анотація: This work is the second part of our study to develop alternative experimental mathematic models for predecting toxicity of insecticides, where we carried out a statistical analysis and comparative estimation of the toxicometric parameters obtained experimentally and calculated according to the proposed equations. In the first stage calculations were carried out and the most reliable models were proposed. The purpose of the research is the scientific substantiation and statistical analysis of the calculation models for predicting the toxicity of insecticides of different classes. For research we took the insecticides of the following chemical classes: neonicotinoids, pyrethroids, organophosphorus compounds. Statistical analysis of the linear and nonlinear regression equations obtained for insecticides was conducted. The equations described the dependence of subthreshold doses in the chronic experiment of all insecticides, the median lethal doses at oral admission of pyrithoids and neonicotinoids from molecular weight; and toxicometry parameters of all insecticides and their individual groups (pyrithoids, neonicotinoids, organophosphorus compounds) on melting temperature and the octanol-water partition coefficient
Дод.точки доступу:
Vavrinevych, O. P.
Shpak, B. I.
Antonenko, A. M.
Omelchuk, S. T.
Zinchenko, T. I.