Форма документа : Стаття із журналу Шифр видання : Автор(и) : Kovalevska L. M., Malysheva T. A., Kalman S. S., Rozumenko A. V., Verbova L. V., Rozumenko V. D., Kashuba E. V. Назва : Expression pattern of MRPS 18 family genes in gliomas Місце публікування : Experimental Oncology. - К., 2021. - Том 43, N 3. - С. 204-208 (Шифр ЕУ12/2021/43/3) MeSH-головна: ГЕННАЯ ЭКСПРЕССИЯ -- GENE EXPRESSION ГЛИОМА -- GLIOMA ГЛИОБЛАСТОМА -- GLIOBLASTOMA БИОЛОГИЯ КОМПЬЮТЕРНАЯ -- COMPUTATIONAL BIOLOGY Анотація: To assess expression patterns of MRPS18 family genes in glioblastoma tissues and glioma cell lines. Materials and Methods: Expression of MRPS18 family genes was analyzed by quantitative polymerase chain reaction in glioma cell lines and glioblastoma specimens. A bioinformatic analysis of the publicly available data on the expression of these genes was also provided. Results: The genes of MRPS18 family show different expression patterns in glioblastomas and glioma cell lines. The highest levels of expression were found for MRPS18-2 at mRNA and protein levels in both glioblastomas and glioma cell lines; the lowest — for MRPS18-1 at mRNA level. Conclusions: The elevated levels of relative expression of the MRPS18-2 gene are characteristic for glioma tumor tissues and cell lines Дод.точки доступу: Kovalevska, L. M. Malysheva, T. A. Kalman, S. S. Rozumenko, A. V. Verbova, L. V. Rozumenko, V. D. Kashuba, E. V.