Форма документа : Стаття із журналу Шифр видання : Автор(и) : Rawoot S., Punatar C., Singh V., Anand A., Shah B., Nagaonkar S., Joshi V. Назва : Neutrophil to lymphocyte ratio as a prognostic marker for non-metastatic renal cell carcinoma - does it add to what we already know? Місце публікування : Experimental Oncology. - К., 2021. - Том 43, N 3. - С. 247-251 (Шифр ЕУ12/2021/43/3) MeSH-головна: КАРЦИНОМА ПОЧЕЧНО-КЛЕТОЧНАЯ -- CARCINOMA, RENAL CELL НЕЙТРОФИЛЫ -- NEUTROPHILS ЛИМФОЦИТЫ -- LYMPHOCYTES ПРОГНОЗИРОВАНИЕ -- FORECASTING Анотація: To study the correlation of pre-operative neutrophil to lymphocyte ratio (NLR) with pathological stage, Fuhrman grade, sarcomatoid differentiation, tumor necrosis and lymph node positivity and its prognostic role in non-metastatic renal cell carcinoma (non-mRCC). Materials and Methods: This retro-prospective, observational study was done at a tertiary care center in Mumbai, India. All patients with non-mRCC from July 2015 to April 2018 were included. Patients with co-existing systemic infection, prior immunotherapy, and long-term steroids were excluded. NLR closest to surgery, but within one month prior to surgery was used. Patients were stratified as NLR ≥ 3.0 or 3. NLR was correlated with known prognostic factors by Pearson’s correlation. Results: 113 patients, aged 18–81 years (83 males and 30 females) were included. 75% had clear cell RCC. 62% had stage 1 disease. 58% patients had Fuhrman Grade 2. 10 patients had lymph node metastasis, 6 had sarcomatoid differentiation, 40 had tumor necrosis. The NLR was 3 in 72 patients. Statistically significant correlation between NLR and tumor stage (p Дод.точки доступу: Rawoot, S. Punatar, C. Singh, V. Anand, A. Shah, B. Nagaonkar, S. Joshi, V. |