Форма документа : Стаття із журналу Шифр видання : Автор(и) : Akinrodoye Abimbola Racheal Назва : Concentration of interleukin-8 in school-age children with non-hospital pneumonia Місце публікування : Український науково-медичний молодіжний журнал. - 2022. - № 1 спецвип. . - С. 5 (Шифр УУ14/2022/1 спецвип.) MeSH-головна: ПНЕВМОНИЯ -- PNEUMONIA ДЕТИ -- CHILD ИНТЕРЛЕЙКИН-8 -- INTERLEUKIN-8 Анотація: In community-acquired pneumonia (CAP), cytokines play a leading role in specific mediators of the immune response. Interleukin-8 is an inflammatory cytokine, a specialized mediator that regulates neutrophil chemotaxis, a product of macrophages and endothelial cells. Disruption of the production, secretion and reception of pro-inflammatory cytokines leads to deep defects in anti-infective protection and exacerbates the direct damaging effects of microorganisms and their toxins on lung tissue. The purpose of the work In order to study the role of cytokines in the formation of the inflammatory process in pneumonia, their impact on the course of the disease, we determined the concentration of interleukin-8 (IL-8) in the serum of children with severe CAP