Вид документа : Статья из журнала Шифр издания : Автор(ы) : Chayka A. V., Zaben’ko Y. Y., Labunets I. F., Pivneva T. A. Заглавие : Traumatic brain injury: pathogenesis, experimental models, prospects of cell-based therapy Место публикации : Клітинна та органна трансплантологія. - 2017. - Том 5, N 2. - С. 209-215 (Шифр КУ53/2017/5/2) Примечания : Bibliogr. at the end of the art. MeSH-главная: ЧЕРЕПНО-МОЗГОВЫЕ ТРАВМЫ -- CRANIOCEREBRAL TRAUMA СТРОМАЛЬНЫЕ КЛЕТКИ МЕЗЕНХИМНЫЕ -- MESENCHYMAL STROMAL CELLS БОЛЕЗНЬ, МОДЕЛИ НА ЖИВОТНЫХ -- DISEASE MODELS, ANIMAL КЛЕТОЧНАЯ И ТКАНЕВАЯ ТЕРАПИЯ -- CELL- AND TISSUE-BASED THERAPY НЕЙРОТРОФИЧЕСКИЕ ФАКТОРЫ ГЛИАЛЬНОГО ПРОИСХОЖДЕНИЯ -- GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS РЕЦЕПТОРЫ СОСУДИСТОГО ЭНДОТЕЛИАЛЬНОГО ФАКТОРА РОСТА -- RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR МЕДИЦИНА РЕГЕНЕРАТИВНАЯ -- REGENERATIVE MEDICINE Аннотация: Traumatic brain injury is the brain damage caused by external mechanical force, for example: a severe impact as a result of a car accident, a blow of a blast wave, biomechanical damage to the brain as a result of a collision with contact sports, etc. This is a complex trauma with a wide range of symptoms became the main cause of death and disability in modern society throughout the world. The results of numerous therapeutic approaches to treating the consequences of injuries have shown promising perspectives in animal models of traumatic brain injury, but have not achieved any significant efficacy in clinical trials. In this review, we will consider the current topical issues of traumatic brain injury: a modern classification; general principles of the development of the pathological process; models of brain trauma in animals; therapy with the application of stem cells of various genesis Доп.точки доступа: Chayka, A. V. Zaben’ko, Y. Y. Labunets, I. F. Pivneva, T. A.