Вид документа : Статья из журнала Шифр издания : Автор(ы) : Kondratyuk V. E., Petrova A. S., Karpenko O. V., Ostashevskaya T. G., Krasyuk E. K. Заглавие : Interrelation between disorder of melatonin-forming function of epiphysis and dyslipidemia in patients with chronic kidney disease of V stage treated by hemodialysis Место публикации : Сімейна медицина. - К., 2020. - № 1/2. - 112-120 (Шифр СУ21/2020/1/2) Примечания : Bibliogr. at the end of the art. MeSH-главная: ПОЧЕК БОЛЕЗНИ -- KIDNEY DISEASES ГЕМОДИАЛИЗ -- RENAL DIALYSIS МЕЛАТОНИН -- MELATONIN ДИСЛИПИДЕМИЯ -- DYSLIPIDEMIAS ХОЛЕСТЕРИН -- CHOLESTEROL ТРИГЛИЦЕРИДЫ -- TRIGLYCERIDES ЛИПОПРОТЕИНЫ -- LIPOPROTEINS БЛЯШКА АТЕРОСКЛЕРОТИЧЕСКАЯ -- PLAQUE, ATHEROSCLEROTIC Аннотация: The results of a number of studies have proved the relationship between the functional state of the pineal gland and renal function. However, violations of the melatonin-forming function of the epiphysis (MFE) in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD) and its relationship with dyslipidemia in this patient population is a poorly understood issueFor patients with CKD of 5 stage undergoing hemodialysis, there is a frequent violation of MFE (84.6%) and significant disorders of lipid metabolism (58%). Analysis of the lipid metabolism study revealed more profound abnormalities in the form of an increased concentration of TC and all its fractions in patients with impaired MFE, which may indicate a connection between epiphysis dysfunction and lipid metabolism in patients with RRT. In patients with hemodialysis, melatonin-forming dysfunction and disorders of lipid metabolism are age-dependent and are determined by the duration of RRT, the duration of hypertension, the level of hemoglobin. We have identified a relationship between the deterioration of lipid metabolism on the background of deeper disturbance of MFE by daytime and nighttime MT Доп.точки доступа: Kondratyuk, V. E. Petrova, A. S. Karpenko, O. V. Ostashevskaya, T. G. Krasyuk, E. K.