Бібліотека Вінницького національного медичного університету ім. М.І.Пирогова

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Type of document : Magazine article
Edition cipher :
Author(s) : Akhmedova S.
Title : Performance results of the improved working classification of superficial mycoses of the skin carrying out their clinical and epidemiological monitoring
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 160-166 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ДЕРМАТОМИКОЗЫ -- DERMATOMYCOSES
ARTHRODERMATACEAE -- ARTHRODERMATACEAE
МИКОЗЫ -- MYCOSES
ОНИХОМИКОЗ -- ONYCHOMYCOSIS
МОНИТОРИНГ ФИЗИОЛОГИЧЕСКИЙ -- MONITORING, PHYSIOLOGIC
Annotation: The results of testing of the improved working classification of superficial mycoses of the skin and its appendages (SMS) in the Republic of Azerbaijan for the period of 2012-2016 are presented. Given the variety of classifications of fungal skin diseases, many years of clinical experience have shown that none of them fully meets the requirements of a practicing physician. The author has developed and improved the classification of mycoses of the skin and its appendages, which will facilitate the diagnosis and the appointment of therapy, since this classification takes into account the tissue and topographic localization of the mycotic process, which greatly facilitates the diagnosis by dermatovenerologists, and will also reveal the true prevalence of mycotic pathology. Based on the traditional form No. 9, among 246 cases of superficial mycoses of the skin and its appendages identified in the city of Baku for the period of 2012-2016, the largest number of patients (79.44±2.6%) were diagnosed with mycoses of the scalp – 32, 52±1.21%, smooth skin mycoses – 30.08%±1.28 multi-colored lichen – 14.80%±1.01, which corresponds to the frequency of occurrence of these forms of SMS at the age of 11-20 years (44.01±3,1%) and 0-10 years (39.08±3.1%), leaders in the age line of groups with SMS in Baku. A reliable statistical difference was revealed in the detection of superficial mycoses of the skin and its appendages in the city of Baku during the study period. Based on the developed working classification, the nosological structure of the incidence of SMS in the city of Baku for the period 2012-2016 is represented by the following – 1919 episodes: mycoses of the scalp – 675 patients (35.17±1.1%); mycoses of smooth skin – 638 patients (33.25±1.1%); multi-colored lichen – 264 patients (13.76±0.8%); combined mycoses of smooth skin and scalp – 134 patients (6.98±0.6%); onychomycoses – 97 patients (5.05±0.5%); purulent-infiltrative form of mycoses – 66 patients (3.44±0.4%); skin candidiasis – 19 patients (0.99±0.2%); feet of the mycoses – 19 patients (0.99±0.2%); inguinal epidermophytosis – 7 patients (0.36±0.1%). The prevalence of nosologies preserved in the largest number of patients (1578 patients – 82.23±0.9%), mycoses of the scalp – 35.17±1.1% (675 patients), smooth skin mycoses – 33.25±1.1% (638 patients), multicolored lichen – 13.76%±0.8 (264 patients). The greatest number of patients with SMS was also detected in the age group of 11-20 years (42.12±3.1%) and 0-10 years (40.32±3.1%). The data of a comparative analysis of the results of the developed and improved classification of superficial mycoses of the skin and its appendages with the data of the traditional reporting form, made it possible to expand the scope of the analyzed nosologies and increase the objectivity of statistical data for assessing the epidemiological situation in the study region
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Type of document : Magazine article
Edition cipher :
Author(s) : Vintoniv O. R., Popadynets I. R. , Hrodzinskyy V. I., Melnyk S. V., Herych P. R., Halipchak I. M.
Title : Algorithm of diagnostics of erectile dysfunction in patients with arterial hypertension and dynamics of arterial blood pressure against the background of androgenic deficiency
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 119-125 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ГИПЕРТЕНЗИЯ -- HYPERTENSION
АНДРОГЕНЫ -- ANDROGENS
ЭРЕКТИЛЬНАЯ ДИСФУНКЦИЯ -- ERECTILE DYSFUNCTION
УЛЬТРАСОНОГРАФИЯ ДОППЛЕРОВСКАЯ ДУПЛЕКСНАЯ -- ULTRASONOGRAPHY, DOPPLER, DUPLEX
Annotation: In recent years, the requirements for the level of the life quality have increased significantly; an integral part of it is the sexual harmony, which in men largely depends on sexual desire and erectile function. According to the results of modern scientific studies, there is no doubt that erectile dysfunction in men is closely connected with the cardiovascular diseases, obesity, diabetes mellitus and other comorbidities. This problem can also be caused by systematic psycho-emotional overload, deterioration of the environmental conditions, harmful factors of production, uncontrolled use of medicines, inflammatory processes in the genital organs, the growth of somatic diseases. The vast majority of works concerning “male menopause” is reduced to the effectiveness of hormone-replacement therapy in erectile dysfunction, while only few research works are devoted to the study of the connection between somatic pathology and androgen deficiency. There is a negative correlation between total testosterone level and systolic blood pressure. According to the research results of some scientists, it was found that 38% of patients with arterial hypertension had androgen deficiency, confirmed in the laboratory, which is significantly higher than in patients of the same age category with normal blood pressure. These dominant factors exert and increase the influence on each other, which must be taken into account in modern therapeutic practice. The study of the formation of comorbid conditions in men with low levels of androgens is of particular importance, as the knowledge of pathophysiological mechanisms can prevent their development and progression. The aim of this investigation was to study the state of penile vascular blood flow in men with arterial hypertension with erectile dysfunction, using color Doppler imaging with pharmacological induction of erection. The indicators of daily monitoring of arterial pressure and arterial stiffness in men with arterial hypertension of the II degree against the background of androgen deficiency or at normal testosterone levels and ways of correction of erectile dysfunction in these patients were also evaluated
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Type of document : Magazine article
Edition cipher :
Author(s) : Aliyeva, Irada J.
Title : Comparative assessment of changes in the incidence of type i diabetes mellitus in the regions with its high and low incidence
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 180-187 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ДИАБЕТ САХАРНЫЙ, ТИП 1 -- DIABETES MELLITUS, TYPE 1
ДИАБЕТИЧЕСКАЯ РЕТИНОПАТИЯ -- DIABETIC RETINOPATHY
ЭПИДЕМИОЛОГИЧЕСКИЕ МЕТОДЫ, ИЗУЧЕНИЕ ПРИЧИННО-СЛЕДСТВЕННЫХ СВЯЗЕЙ -- INTERVENTION STUDIES
Annotation: The purpose of this study was to determine dynamics of the levels of type I diabetes mellitus (DM) incidence in the regions with its different incidence. Material from the Azerbaijan Republican and Regional Registers of Diabetes Mellitus were used in this study. All cases of newly diagnosed type 1 DM and documented according to the clinical protocol in 2012-2016 were selected. At the first stage of the study, the rates of diabetes were identified in all administrative-territorial entities. Two groups from administrative-territorial entities were formed for further observation: the first group included regions with high (80) incidence of type 1 DM, the second group included regions with low (40) incidence of type 1 DM. At the next stages, changes in type 1 DM incidence were studied and a mean chronological incidence over five years (2012-2016) was determined. Morbidity rate in cities and regions of Azerbaijan in 2012 changed within a range from 5.4 to 294.8. The lowest incidence was observed in three districts: 5.4 in Agjabedi, 5.8 in Jalilabad, 6.1 in Masalli. Very high incidence was observed in Shamkir (294.8) and Khachmaz (278.7) districts. Data from Agdash (30.6) and NAR (32.2) were closer to data from the districts with low incidence. Incidence in Shirvan (81.9) and Yexlakh (171.7) districts was high, but lower than in Shamkir and Khachmaz districts. Type 1 DM incidence has significant interregional differences. Interregional differences in type 1 DM incidence do not depend on the age of the population; age-adjusted incidence of type 1 DM is within a range of 5.0-77.4
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Type of document : Magazine article
Edition cipher :
Author(s) : Shkodina A. D. , Grinko R. M., Starchenko I. I., Vynnyk N. I., Sovhyria S. M. , Kyslyi V. F.
Title : Changes of structural organization of human olfactory bulbs under conditions of severe forms of pneumonia and cerebrovascular pathology
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 97-104 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ОБОНЯНИЯ РАССТРОЙСТВА -- OLFACTION DISORDERS
ПНЕВМОНИЯ -- PNEUMONIA
МОЗГОВОГО КРОВООБРАЩЕНИЯ РАССТРОЙСТВА -- CEREBROVASCULAR DISORDERS

Annotation: The role of human olfactory bulbs remains one of the most interesting questions concerning work of the brain, because this organ is one in which neurogenesis is continuously generated in post-natal and adult periods. Impaired sense of smell is not a pathology that threatens human life, therefore, often remains unnoticed. However, it can directly affect the quality of life, as it leads to malnutrition and certain problems in interpersonal relationships. The study of the functional structure of the olfactory analyzer plays an important role both in clinical and experimental studies, but the question of its features in humans needs detailed research. The material of the research was 18 pairs of the olfactory bulbs of males and females aged from 30 to 90 years that were received at the Poltava Regional Department of Pathology. In order to objectify the data obtained on micropreparations, the following morphometric indices were determined: the specific gravity of the location of cellular elements; the proportion of mitral neurocytes in the entire cell population; percentage ratio of relative quantity between cellular elements, blood microvessels, fibrillar component and homogeneous eosinophilic structures. Correlation analysis of morphometric indices in the general sample revealed the existence of an inverse communication of average strength between the relative number of homogeneous eosinophilic cells and the relative number of cellular elements and blood microvessels, which in turn indicates the etiopathogenetic mechanisms of the formation of these structures. The conducted research makes it possible to conclude that mitral cells as one of the most differentiated in olfactory bulbs are sensitive to the development of hypoxic states; under the conditions of cerebrovascular pathology, the relative amount of the blood vessels of the microvessels decreases, which leads to the disorder of the trophy of the nervous tissue and as a result can lead to neurocytolysis of mitral cells. Changes in the vascular and cellular component indicate a different pathogenesis of changes in human olfactory bulbs in these pathologies and suggest that eosinophilic homogeneous cells are the result of apoptotic neurocytolysis against the background of development of hypoxic states
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Type of document : Magazine article
Edition cipher :
Author(s) : Kulikova D. A., Safanova I. N. , Chumak I. I., Poddubnaya I. N., Protsenko O. S., Dotsenko D. G.
Title : Determining hemodynamic significange of patent ductus arteriosus using echocardographic data prognostic tables
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 52-58 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: АРТЕРИАЛЬНЫЙ ПРОТОК -- DUCTUS ARTERIOSUS
ГЕМОДИНАМИКА -- HEMODYNAMICS
ЭХОКАРДИОГРАФИЯ -- ECHOCARDIOGRAPHY
Annotation: The paper presents an analysis of echocardiographic data of patients with PDA having different hemodynamic significance. Presently, the concept of “degree of hemodynamic significance” remains controversial. Criteria for determining the hemodynamic significance of PDA in term infants are not described. In our work, we used a classification of three degrees of hemodynamic significance: non-hemodynamically significant PDA – insignificant, moderately hemodynamically significant – moderately significant and large PDA – hemodynamically significant PDA. Aim – to work out an algorithm for determining the degree of PDA hemodynamic significance for prediction of its further development. The study involved children under 18 years old (80% of them ‒ children under 3 years old) who were examined in the cardiac surgery department of the SI “IGUS n.a.V.T. Zaytsev NAMS of Ukraine” during 2013-2017 yy. Gestational age (from 37 weeks), the presence of left to right PDA shunt, absence of a ASD shunt and other congenital heart defects served as enrollment criteria for the trial. Two prognostic tables were formed with the main criteria for determining hemodynamic significance of PDA by the sum of the signs according to gradations (insignificant, moderately significant and hemodynamically significant) as an outcome of the trial. Based on the determination of the main and additional criteria of hemodynamic significance and the strength of their influence, a diagnostic algorithm is formed for a patient with PDA with the possibility of predicting a further clinical scenario. For determination of hemodynamic significance, an increase in pulmonary gradient with an information index of 1.135 and a prognostic factor of +5.90/-1.75 were dominant, while the left ventricular dilatation located from the A4C with an informational index of 1.020 and a prognostic coefficient of +3.69/-2.50 dominated in determining the degree of hemodynamic significance in the presence of secondary changes. The proposed mechanism for determining the level of hemodynamic significance of PDA for children with borderline changes will predict more precisely the development of the disease, determine the patient’s observation tactics and regulate the decision-making process of surgical intervention
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Type of document : Magazine article
Edition cipher :
Author(s) : Kirieieva T. V., Pertseva T. A. , Kravchenko N. K., Basina B. O.
Title : Genetic testing for thrombophilia in case of unprovoked episode of pulmonary embolism
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 197-201 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ТРОМБОЭМБОЛИЯ -- THROMBOEMBOLISM
ТРОМБОФИЛИЯ -- THROMBOPHILIA
КОЭФФИЦИЕНТ РАЗЛИЧИЙ В ЧАСТОТЕ СЛУЧАЕВ -- ODDS RATIO
Annotation: Venous thromboembolism (pulmonary embolism (PE) and deep vein thrombosis (DVT)) is the third among all cardiovascular syndromes in the world, second only to heart attack and stroke. Estimation of clinical probability of this condition takes into account many factors, including age. But in case of PE probability in young patient data of scales such as Geneva Score (Revised), Wells’ criteria for pulmonary embolism, the PERC rule may be misleading. For this group a new influential factor emerges – thrombophilia. The aim of our work was to demonstrate the approach to identifying whom and when to test for genetic predisposition for thrombosis, based on a clinical case of young male with unprovoked episode of PE. Testing patients for thrombophilia is a good way to develop a personalised approach in case of prescribing long-term anticoagulant treatment. Moreover, patient’s awareness about congenital condition helps to increase complience which is crucial, due to the fact that in case of unprovoked pulmonary embolism another episode can occur in up to 50 % of cases during the next 5 years. In addition, further accumulation and analysis of data on the amount of genetic risk factors for thrombosis will expand our understanding of this issue and in the future will allow us to better diagnose and treat this condition
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Type of document : Magazine article
Edition cipher :
Author(s) : Bilovol O. M., Kniazkova I. I., Zemlianitsyna O. V., Dunaeva I. P., Romanova I. P., Kurilo O. D., Sinaiko V. M., Kravchun N. O.
Title : Heratic fibrosis as anadditional risk factor for the development of cardiovascular disorders in patients with type 2 diabetes mellitus with non-alcoholic fatty liver disease
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 126-134 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ДИАБЕТ САХАРНЫЙ, ТИП 2 -- DIABETES MELLITUS, TYPE 2
ПЕЧЕНИ ЖИРОВАЯ ДИСТРОФИЯ -- FATTY LIVER
СЕРДЕЧНО-СОСУДИСТЫЕ БОЛЕЗНИ -- CARDIOVASCULAR DISEASES
ЦИРРОЗЫ ПЕЧЕНИ -- LIVER CIRRHOSIS
Annotation: The aim of the study was to determine the relationship between the degree of progression of liver fibrosis and the risk of cardiovascular complications in patients with Type 2 diabetes mellitus (DM) with non-alcoholic fatty liver disease (NAFLD). The study included 110 patients with Type 2 diabetes (62 men and 48 women), the average age of the subjects was 52.07±1.11 years. All patients were divided into 2 groups: the main group included 72 patients with Type 2 diabetes with concomitant NAFLD (38 men and 34 women); the control group included 38 patients with Type 2 diabetes without clinical manifestations of NAFLD (24 men and 14 women). Patients of the main group were divided into 3 subgroups, taking into account the predominant pathological processes in the clinical picture. The division into subgroups was carried out in 2 stages: at the first stage, those with predominant manifestations of liver fibrosis (F2 or more) were selected from the general population of patients with Type 2 diabetes with NAFLD according to the results of liver elastography and the use of Bonacini and Metavir scales. The number of such patients was 29, which accounted for 40.3% of the total number of patients in the main group. The remaining patients were divided into 2 subgroups: 11 patients (15.3%) had non-alcoholic liver steatosis, and 32 patients (44.4%) had signs of non-alcoholic steatohepatitis (NASH). As a result of the study, it was found that the presence of liver fibrosis in patients with Type 2 diabetes with NAFLD is significantly more often associated with cardiovascular complications, such as arterial hypertension, coronary heart disease, myocardial infarction, stroke, diabetic retinopathy and nephropathy. A significant decrease in the ejection fraction (EF) was found in patients with Type 2 diabetes with concomitant NAFLD. At the same time, the number of patients with EF disorders of varying degrees in the main group significantly exceeded that in the comparison group (33.3% and 6.7%, respectively, p0.001). The average values of left ventricular myocardial mass are significantly lower in patients with NASH and fibrosis formation compared to patients with NAFLD at the stage of fatty hepatosis. There was also a significant decrease in the size of the left and right atria in patients with NASH compared to both patients with steatosis and patients with fibrotic liver changes. Patients with predominant fibrotic changes in the liver are characterized by a relative decrease in myocardial mass, a decrease in final diastolic and systolic volumes and EF, which may indicate the development of diastolic dysfunction in them. It is shown that it is necessary to take into account in clinical practice not only the generally accepted stages of NAFLD, but also the predominant pathological process in the liver in patients with Type 2 diabetes, namely steatosis, manifestations of inflammation and fibrotic disorders. It is proved that fibrotic changes in the liver can develop at all stages of liver tissue damage
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Type of document : Magazine article
Edition cipher :
Author(s) : Kopchak O. V., Yakovenko L. F., Marchenko N. S., Kovach I. V., Pavlenko E. M., Nimenko O. A., Kroupskaya I. V. , Filonenko V. V.
Title : Llevels of Hsp60 in periodontal tissue of rats: influence of injections of hyaluronic acid
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 12-18 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: АУТОАНТИГЕНЫ -- AUTOANTIGENS
ПЕРИОДОНТА БОЛЕЗНИ -- PERIODONTAL DISEASES
ГИАЛУРОНОВАЯ КИСЛОТА -- HYALURONIC ACID
КРЫСЫ ЛИНИИ WISTAR -- RATS, WISTAR
Annotation: Heat shock protein 60 (Hsp60) is considered as one of the possible autoantigens involved in the pathogenesis of a number of chronic diseases including periodontal diseases. The application of hyaluronic acid or hyaluronan (HA) in the treatment of periodontitis has been evaluated in several clinical trials, however, the effect of hyaluronic acid on heat shock protein 60 level in periodontal soft tissues has not been studied. The aim of this work was to evaluate the effect of HA injections on levels of Hsp60 in periodontal tissue of the rats. Samples of periodontal tissue of mandibular incisors of adult male Wistar rats at 10-12 months of age were investigated. Rats were distributed into the control group and the periodontitis group. Visual manifestations of hyperemia of the gums around the incisors were the criterion for selecting animals into the periodontitis group. There were two subgroups in the control group: intact rats (I); intact rats after HA “hyaDENT BG” 1.0 MDa (BioScience GmbH, Germany) treatment (I+“G-1.0”). There were four subgroups in the periodontitis group: rats with periodontitis (P); rats with periodontitis after HA “hyaDENT BG” 1.0 MDa (BioScience GmbH, Germany) treatment (P+“G-1.0”); rats with periodontitis after HA “SERTOBEC” 2.4 MDa (S.C. Rompharm Company S.R.L., Romania) treatment (P+“S-2.4”); rats with periodontitis after HA “SERTOBEC Tendon” 2.4 МDа (S.C. Rompharm Company S.R.L., Romania) treatment (P+“ST-2.4”). There were three animals in each subgroup. Rats were injected 0.05 ml HA in the area of alveolar processus of central incisors once a week, three times. Levels of Hsp60 in total lysates of periodontal tissue were tested by Western blotting method before and after the treatment with HA (one month after the last injection). There was no significant difference between levels of Hsp60 in total lysates of periodontal tissue of intact rats and rats with periodontitis before treatment (p0.05). Rats with periodontitis showed decreased inflammation in the periodontal tissue after treatment with HA with different molecular weight. Intact rats and rats with periodontitis which were treated with HA “hyaDENT BG” 1.0 MDa showed reduced levels of Hsp60 in total lysates of periodontal tissue comparatively with levels of Hsp60 before treatment (by 15.4 and 10.7 times respectively, p0.001). Rats with periodontitis which were treated with HA “SERTOBEC” 2.4 MDa or HA “SERTOBEC Tendon” 2.4 MDa also showed reduced levels of Hsp60 in total lysates of periodontal tissue comparatively with levels of Hsp60 before treatment (by 21.3 and 16.4 times respectively, p0.001). Rats with periodontitis showed the decrease in inflammation in periodontal tissue after treatment with HA with different molecular weight. Injections of HA has contributed to reduce levels of Hsp60 in periodontal tissue of intact rats and rats with periodontitis
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Type of document : Magazine article
Edition cipher :
Author(s) : Melnychuk M. P.
Title : Clinical significance of high grade and low grade prostate intraepithelial neoplasia
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 134-140 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ НОВООБРАЗОВАНИЯ -- PROSTATIC NEOPLASMS
ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ ИНТРАЭПИТЕЛИАЛЬНАЯ НЕОПЛАЗИЯ -- PROSTATIC INTRAEPITHELIAL NEOPLASIA
НЕОПЛАСТИЧЕСКИЕ ПРОЦЕССЫ -- NEOPLASTIC PROCESSES
Annotation: Such premalignant conditions of prostate cancer (PC) as prostate intraepithelial neoplasia (PIN) are classified between benign and malignant ones. Contemporary evidence wheather PIN develops malignancy is limited and (LGPIN) data present varied results. Morphological and clinical differencies between high (HGPIN) and low grade PIN specimens in the prostate remain unclear. Aim of the work – to determine clinical significance and progression ability of high grade and low grade prostate intraepithelial neoplasia. The results of examination of 276 patients with PIN (152 patients with high grade PIN and 134 patients with low grade PIN) were assessed comparatively. During a 3 year follow-up repeated prostate biopsies were performed with 6 months interval to detect PC. Initial and repeated multifocal transrectal prostate biopsies from 12 samples were performed under transrectal ultrasonic guidance. There were statistically significant differences in PC detection rates between HGPIN and LGPIN. Patients with HGPIN had malignization rate of 42.1% during a 3-year follow-up that was by 33.9% higher than in LGPIN patients. The spread of HGPIN lesions within prostate gland is a malignization risk factor. The mean malignization term of HGPIN is 18 months and of LGPIN – 30 months. Low and high grade PIN are gradual stages of cancerogenesis. PIN grade determines its clinical significance, while LGPIN has low malignization potential, HGPIN possesses morphological and clinical prostate characteristics similar to adenocarcinima
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10.

Type of document : Magazine article
Edition cipher :
Author(s) : Mirchuk B. M., Maksymov Y. V.
Title : Orthodontic treatment of secondary deformations in adult patients with defects of dentition
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 104-110 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ДЕНТАЛЬНОЙ ПЛАСТИНКИ ИМПЛАНТАЦИЯ -- BLADE IMPLANTATION
ЗУБНОЙ РЯД ПОСТОЯННЫЙ -- DENTITION, PERMANENT
ЧЕЛЮСТНО-ЛИЦЕВЫЕ ДЕФОРМАЦИИ -- DENTOFACIAL DEFORMITIES
ЗУБНЫЕ ПРОТЕЗЫ
ЗУБ ИСКУССТВЕННЫЙ -- TOOTH, ARTIFICIAL
ОРТОДОНТИЧЕСКИЕ СКОБКИ -- ORTHODONTIC BRACKETS
ЗУБНАЯ ДУГА -- DENTAL ARCH
Annotation: In the presence of dentition defects there is a complex of morphological, aesthetic and functional changes that significantly complicate the process of diagnosis and treatment of this pathology. Dentition defects, combined with various dental anomalies and deformations very often impede rational prosthetics and at times make it impossible at all. The aim is to increase the effectiveness of orthodontic treatment of secondary deformations in patients with dentition defects by using primary dental implants as an additional skeletal support. For clinical evaluation of the effectiveness of treatment of secondary deformations in 20 patients with partial dentition defects there was performed orthodontic treatment using a straight arc technique with metal braces of the Roth system and primary detailed one-component implants as an additional skeletal support. On the diagnostic models of the jaws, the meso-distal dimensions of the lost teeth and their possible position in the dentition were determined, the shape of the dentition by methods of Pon and Korkhaus, the position of the teeth in the area of dentition defects was analyzed and the jigs of occlusion according to Andrews were defined. The use of primary dental implants as an additional skeletal support in the area of dentition defects makes it possible to control the rotation of the teeth and at the same time to use orthodontic forces of different intensity during their distal or mesial movement. As a result of orthodontic treatment of secondary deformations, we managed to achieve positive changes in the normalization of angles of dental inclination that limit the defect in patients with dentition defects. Along with the normalization of the angles of dental inclination (torque and angulation) which limit dentition defects we have noticed an increase in the distance between these teeth, which allows to restore dentition defect with dentures, better corresponding to the size of the lost teeth. Important, in our opinion, is the possibility, when using a primary dental implant as an additional skeletal support, to use the technique of segmental braces. The use of primary dental implants in the area of the dentition defect as an additional skeletal support makes it possible to restore angulation and torque of the teeth, which limit the defect, using orthodontic forces of different intensity. As a result of orthodontic treatment of secondary deformations, the distance between teeth limiting dentition defects on the upper jaw increased on average by 2.39 mm (p0.001) and on the lower jaw – by 2.57 mm (p0.001)
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11.

Type of document : Magazine article
Edition cipher :
Author(s) : Smorodska O. M., Moskalenko Yu. V., Vynnychenko I. O., Vynnychenko O. I., Kostuchenko V. V.
Title : Modern vector in treatment of patients with lung cancer: tyrosine kinase inhibitors in Epidermal Growth Factor Receptor mutations (literature review)
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 4-11 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
Subject headings: Эрлотиниб
Гефитиниб
Афатиниб
Осимертиниб
MeSH-main: КАРЦИНОМА НЕМЕЛКОКЛЕТОЧНАЯ ЛЕГКОГО -- CARCINOMA, NON-SMALL-CELL LUNG
ДНК ПОВРЕЖДЕНИЕ -- DNA DAMAGE
Annotation: Tumor molecular profiling in patients with non-small cell lung cancer (NSCLC) is used to identify driver mutations, which lead to premature carcinogenesis in more than 80% of adenocarcinoma cases, including epidermal growth factor receptor (EGFR) mutations. Identification of specific somatic aberrations allows to personalize treatment. Personalization of treatment resulted in improvement of NSCLC outcomes. The aim of our study was to consider scientific data on modern concepts of treatment of patients with non-small cell lung cancer with previously detected oncogenic mutations, especially EGFR mutation. In our study we analyzed scientific papers and data of international scientific literature on the problem of lung cancer treatment. Methods used: scientific research, analytical and generalizing. Different drugs are used in treatment of lung cancer. Choice of treatment scheme depends on type and presence of mutations. Patients with advanced non-small-cell lung cancer and detected mutation in the EGFR can be treated with tyrosine kinase inhibitors (TKIs). Nowadays three first generation drugs are recommended by FDA: afatinib, erlotinib, gefitinib. They showed good clinical benefit. Most patients with metastatic NSCLC typically show disease progression after approximately 9 to 13 months of erlotinib, gefitinib, or afatinib therapy. The first and only commercially available third-generation EGFR TKI is оsimertinib - an oral drug, which selectively inhibits both EGFR-TKI and EGFR T790M resistance mutations. Nowadays scientists are in active investigation of mechanisms of acquired resistance to TKIs, but little is known yet. Clinical success can be observed in patients who were treated with TKIs. EGFR T790M is a mutation that leads to acquired resistance to EGFR TKI therapy. Its incidence is approximately 60% after disease progression on TKI drugs (erlotinib, gefitinib, or aphatinib). Third-generation EGFR TKIs demonstrate high efficacy, but acquired resistance development cannot be avoided. Mechanisms of acquired resistance to these agents are still investigatedМолекулярне дослідження пухлин у пацієнтів з недрібноклітинним раком легень (НДРЛ) використовується для визначення драйверних мутацій, що призводять до раннього канцерогенезу в більше ніж 80% випадках аденокарценоми, включаючи мутацію рецептора епідермального фактора росту (EGFR). Визначення специфічних соматичних мутацій дозволяє лікувати хворих персоналізовано, що приводить до значного покращення результатів лікування НДРЛ. Метою роботи було вивчення проблеми таргетної терапії НДРЛ шляхом аналізу відповідної наукової літератури. В якості досліджуваного матеріалу було використано дані закордонних джерел, які досліджують проблематику лікування раку легень. Науковий пошук, аналіз та узагальнення були обрані в якості методів. Інгібітори тирозин кінази (TKIs) використовують в якості стандартної терапії першої лінії для лікування пацієнтів з недрібноклітинним раком легень, у яких наявна мутація EGFR. До першого покоління інгібіторів тирозин кінази відносять гефітиніб, ерлотиніб, афатиніб. Їх використання показало високі терапевтичні результати. У більшості пацієнтів із мутаціями EGFR та метастатичним недрібноклітинним раком легенів приблизно через 9-13 місяців терапії ерлотинібом, гефітинібом або афтатинібом спостерігається прогресія захворювання. Першим і єдиним комерційно доступним інгібітором рецепторів EGFR третього покоління є осимертиніб. Осимертиніб – оральний, незворотний EGFR-інгібітор третього покоління, який вибірково інгібує як EGFR, так і мутації стійкості до EGFR ‒ T790M. Наразі вчені активно досліджують механізми набутої резистентності до інгібіторів тирозин кінази, проте багато питань досі залишаються невирішеними. Перше покоління інгібіторів EGFR показало клінічний успіх серед пацієнтів, у яких наявна EGFR мутація. Наявність мутації EGFR T790M пов’язують з набутою резистентністю до терапії інгібіторами тирозин кінази. Було показано, що в 60% випадків виявлення вказаних мутацій було зафіксовано після прогресії захворювання за умови початкової відповіді на терапію ерлотинібом, гефітинібом чи афатинібом. Інгібітори тирозин кіназ третього покоління демонстують високу ефективність та не сприяють розвитку набутої резистентності. Мало відомо про механізми розвитку резистентності, тому дослідження в цьому напрямку тривають
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12.

Type of document : Magazine article
Edition cipher :
Author(s) : Pletenetska A. O., Demchenko I. S., Ergard N. M.
Title : Evaluation of the quality of medical care in cases of death from acuteblood loss (according to data of forensic-medical examinations)
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 166-172 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ГЕМОРРАГИИ -- HEMORRHAGE
НЕОТЛОЖНАЯ МЕДИЦИНСКАЯ ПОМОЩЬ -- EMERGENCY MEDICAL SERVICES
КОРОНЕРЫ И СУДЕБНО-МЕДИЦИНСКИЕ ЭКСПЕРТЫ -- CORONERS AND MEDICAL EXAMINERS
СМЕРТИ ПРИЧИНА -- CAUSE OF DEATH
Annotation: The peculiarities and specificity of the medical field complicate not only the assessment of quality and timeliness of medical care, but also the correctness of the choice of the method of treatment and diagnosis of the disease. The number of forensic medical examinations in «medical cases» has the tendency to increase, and experts in this case face difficulties with forensic medical assessment of medical care provision. Forensic medical analysis of the medical care provision to patients who died of acute blood loss, based on examinations of different forensic medical bureaus of Ukraine has been analyzed. The aforementioned examinations related to the corpses of people who died as a result of acute blood loss, including shock (150 from the total number of 6129 medical examinations were selected). This cause of a death was chosen as one of the leading causes of death in trauma (including a combination with shock). When evaluating gross medical care defects that were found during the examinations that influenced the result, 40.0% (60) – in the form of improper provision (action) were noted in 10 cases (the case of incorrect diagnosis made by the doctors due to underestimation of examination data), defects in the form of non-provision of medical care (inactivity) – in 83.3% (15 cases). In the statistical analysis of defects in the provision of medical care, the majority of cases were connected with delayed provision of medical care – 41,7%. Defects in cases of blood loss were under the following conditions: a) lack of instrumental research, medical treatment and surgery, b) lack of medical treatment and surgery by indications (each of 3,3%). When considering the reasons that led to defects in cases of blood loss, the isolated underestimation of the examination data was in 16,7% (25), a combination of reasons: a) underestimation of the examination data together with the underestimation of additional research data – 16,7% (25); b) underestimation of the examination data together with the negligent attitude to the patient who had a sloppy appearance – 6,7%. The unprofessional nature of the medical staff was in 16,7% of acute blood loss. When providing medical care in cases of death from acute blood loss, defects in the provision of medical care are made by experienced medical professionals in city hospitals (especially large cities of Ukraine), where there are adequate conditions for the provision of medical care, more qualified specialists of different profiles, and there are protocols for providing medical care in acute blood loss
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13.

Type of document : Magazine article
Edition cipher :
Author(s) : Demkovych A. Ye., Bondarenko Yu. I., Fastovets O.O., Hrad A. O. , Hasiuk P. A., Denefil O. V.
Title : State of collagenolysis in experimental periodontitis of bacterial-immune genesis and its correction with flavonol
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 26-32 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
Subject headings: Оксипролин
Кверцитин
MeSH-main: ПЕРИОДОНТА БОЛЕЗНИ -- PERIODONTAL DISEASES
ВОСПАЛЕНИЕ -- INFLAMMATION
КОЛЛАГЕНОЗЫ -- COLLAGEN DISEASES
Annotation: The article presents an assessment of the dynamics of changes in the content of the marker of collagenolysis – free oxyproline in the homogeniate of soft tissues and bone in experimental bacterial-immune periodontitis and elucidation of the effect of flavonol quercetin on these indicators. The aim of this study was to determine the role of cytokinogenesis and the effect of flavonol on it in the pathogenesis, development and course of experimental periodontitis. During the experiment, a fragment of the mandible was taken from the animals, from which the soft tissues and bone were carefully separated. The state of collagen was determined by the content of free oxyproline in the soft and bone tissues. The concentration was determined according to the calibration graph and expressed in μmol/g. The results of studies of the indicators of the state of biopolymers of connective tissue structures of periodontium on the 7th, 14th and 30th day of experimental bacterial-immune periodontitis and after its correction with flavonol (from the 7th to the 14th day of the experiment) are presented. The data on the nature of changes in the content of collagen monomers in the process of formation of the inflammatory focus in the periodontal complex are given. During the acute phase of the inflammatory process in rats there was revealed a slight increase in blood free oxyproline in bone homogenate and homogenate of soft periodontal tissues, on the 14th day the dynamics continued to increase, at a later stage of the experiment, namely on the 30th day, increase in bone resorption continued as compared to the 7th and 14th day. During the correction of disorders resulted from the development of this pathological process there was a decrease in the level of free oxyproline in the bone homogenate and homogenate of soft tissues of mandibular periodontium, as compared to the same indicators of animals who did not receive quercetin on the 14th day. The use of flavonol quercetin, which, by affecting immune processes, limited the inflammatory response in periodontal tissues and stabilized collagenolysis processes in periodontal tissues was manifested by a decrease in free oxyproline in bone and soft tissue homogenates of experimental animals
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14.

Type of document : Magazine article
Edition cipher :
Author(s) : Povoroznyuk V. V., Dedukh N. V., Bystrytska M. A., Dzerovych N. I., Shapovalov V. S.
Title : The association of sarcopenia and osteoporosis and their role in falls and fractures
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 111-119 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: САРКОПЕНИЯ -- SARCOPENIA
КОСТЕЙ БОЛЕЗНИ МЕТАБОЛИЧЕСКИЕ -- BONE DISEASES, METABOLIC
ОБМЕНА ВЕЩЕСТВ БОЛЕЗНИ -- METABOLIC DISEASES
ПАДЕНИЯ СЛУЧАЙНЫЕ -- ACCIDENTAL FALLS
ПЕРЕЛОМЫ ПРИ ОСТЕОПОРОЗЕ -- OSTEOPOROTIC FRACTURES
Annotation: The progressive and generalized loss of skeletal muscle mass and strength leads to sarcopenia in elderly people. A new geriatric syndrome has been revealed – osteosarcopenia (osteosarcoporosis), which combines low bone mineral density with reduced muscle mass, strength and functional activity. The review presents data on the peculiarities of manifestation of these syndromes, the mechanisms of which are multifactorial and continue to be investigated. They are associated with genetic factors, lifestyle – lack of physical activity and malnutrition. The pathogenesis of sarcopenia involves mechanisms of chronic inflammation, changes in endocrine function, disturbance of neuromuscular connections and low reparation level. Sarcopenia correlates with low quality of life, disability, and death. The review analyzes the prevalence of sarcopenia which increases with age. However, there are conflicting results in the populations, which may be related to different clinical conditions, patient area, lifestyle and the use of different assessment criteria. The analysis of sarcopenia prevalence in men and women showed ambiguous results related to the studied population, involvement of different age groups of patients, different evaluation methods. Metabolic disorders in muscular and bone tissues were summarized on the basis of the analysis of the cross-influence of regulatory factors and metabolism products of these tissues; a close metabolic and functional association between them was shown. Fat infiltration of atrophied muscles and bone marrow is common in patients with sarcopenia and osteosarcoporosis, which affects muscle and bone tissue. Lipotoxicity and local inflammation stimulate the biosynthesis of pro-inflammatory cytokines. Literature analysis has shown controversial data on the association of sarcopenia and osteosarcopenia with falls and fractures, but based on meta-analysis data, which include an extensive body of information, it should be noted that individuals with sarcopenia and osteosarcopenia are more at risk of falls and fractures and require special special attention. The most common fracture in osteosarcopenia is the hip fracture
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15.

Type of document : Magazine article
Edition cipher :
Author(s) : Valseba T. S. , Sokolova L. K., Tronko M. D., Churpiy I. K., Vatseba M. O., Derpak V. V.
Title : The impact of obesity on the development of certain cancers in patients with type 2 diabetes mechanisms of association
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 88-96 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ОЖИРЕНИЕ -- OBESITY
ДИАБЕТ САХАРНЫЙ -- DIABETES MELLITUS
ФАКТОРЫ РИСКА -- RISK FACTORS
Annotation: The aim of the study was to investigate the effect of obesity on the development of cancer of certain localizations in patients with type 2 diabetes mellitus (T2D) and to explain the association mechanisms of obesity in diabetes and cancer. The study included retrospective analysis of first time diagnosed cancer cases in patients with T2D in 2012-2016 in Ivano-Frankivsk region. Analysis of the data was carried out using Statistica 12.0 (StatSoft Inc., USA) program. The data are presented in the tables as M±SD (M± standard deviation). Differences between the studied parameters were determined using the ANOVA- test, taking into account the Bonferroni correction. The relationship between the studied data was evaluated using the criterion of chi-square with Yates correction (χ²). The odds ratio (OR), 95% confidence interval, the positive and negative predictive value were calculated to determine the association between two events. The differences were considered significant at p0.05. According to the results, 533 cases of the first time diagnosed cancer were detected in patients with T2D. It was found that obesity is inherent in women with breast, uterine, ovarian and colorectal cancer; for men with prostate cancer and with colorectal cancer. According to the criterion of χ², the effect of obesity on the incidence of breast cancer in women (x2
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16.

Type of document : Magazine article
Edition cipher :
Author(s) : Danylenko H. M., Cherniakova G. M., Merkulova T. V., Avdiievska O. H.
Title : The impact of summer holidays on the physical development of school-age children
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 147-152 (Cipher МУ10/2021/26/2)
Notes : Bibliogr. at the end of the art.
MeSH-main: ШКОЛЬНИКИ -- SCHOOL STUDENTS
ФИЗИЧЕСКОГО РАЗВИТИЯ КАРТЫ -- GROWTH CHARTS
ЭФФЕКТИВНОСТЬ ДЕЯТЕЛЬНОСТИ -- EFFICIENCY
ОТДЫХ АКТИВНЫЙ -- RECREATION
Annotation: The aim of the work was to investigate how gender, age and type of activity in summer affects the indicators of physical development (PD) of children. 1054 students (493 boys and 561 girls) aged 7-16 years took part in the study. The PD of children was studied by assessing somatometric and physiometric indicators. To assess the impact of the type of activity, a thematic questionnaire "Summer" was used. It was found that the gender and age of children had a significant effect on PD indicators in the summer. The most intense increase in body length occurred at the age of 7-12 years, body weight - in 10-14-year-olds, and up to 16 years grouth of two parameters gradually slowed down. From the age of 10, children showed a positive increase in lung capacity (LC). In 15-year-old adolescents, a decrease in both indicators (ChC and LC) was found. It was found that 62% of children carried out educational activities in the summer, 24% of those were engaged in business activities, almost 40% of students were participants in hiking trips and 23% of children attended a children’s health camp. The chosen type of activity in the summer influenced the indicators of the pupils’ PD as follows: educational activities were accompanied by a decrease in body length and strength of the left arm, business activity, hiking trips and staying in a health camp were accompanied by an increased weight gain and an increase in LC
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17.

Type of document : Magazine article
Edition cipher :
Author(s) : Іпатов А. В., Саніна Н. А., Ханюкова І. Я.
Title : Оцінка ефективності індивідуальної комплексної реабілітації хворих на засадах міжнародної класифікації функціонування
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 153-159 (Cipher МУ10/2021/26/2)
Notes : Бібліогр. в кінці ст.
MeSH-main: РЕАБИЛИТАЦИЯ -- REHABILITATION
РЕАБИЛИТАЦИИ ЦЕНТРЫ -- REHABILITATION CENTERS
КЛАССИФИКАЦИЯ -- CLASSIFICATION
Annotation: З метою визначення можливості застосування реабілітаційного профілю для оцінки ефективності реабілітації та розробки методики кількісної оцінки ефективності реабілітаційних заходів на короткостроковому інтервалі у стаціонарних хворих на базі Державної установи «Український державний науково-дослідний інститут медико-соціальних проблем інвалідності МОЗ України» було проведено оцінку якості за допомогою створення реабілітаційного профілю пацієнта на основі принципів Міжнародної класифікації функціонування, обмеження життєдіяльності та здоров’я (МКФ). Проаналізовано 522 карти реабілітаційного профілю у хворих з патологією внутрішніх органів, опорно-рухового апарату, захворюваннями органу зору, які перебували на стаціонарному лікуванні. Реабілітація пацієнтів була комплексною, із застосуванням медичної реабілітації, методів психологічної та фізичної реабілітації. Виразність порушень функцій оцінювалася за кількісною шкалою від 0 до 4 балів, де "0" - порушень немає, а "4" - вкрай тяжкі порушення. Оцінювання проводилося членами мультидисциплінарної команди двічі: при первинному огляді пацієнта та після закінчення терміну перебування у клініці. Для обробки результатів дослідження використовувався статистичний метод та метод експертних оцінок. Використовувалося ліцензійне програмне забезпечення MS Excel для Windows. Проведеним дослідженням встановлено, що запропонований метод оцінки ефективності короткострокової реабілітації є точним та об’єктивним, він враховує початковий функціональний статус хворого та дозволяє провести оцінку якості та ефективності реабілітаційних заходів як на рівні пацієнта, так і на рівні установи загалом. Його впровадження дозволить забезпечити єдиний підхід до надання реабілітаційних послуг та зробити висновки щодо ефективності реабілітаційної діяльності медичної установи диференційовано з урахуванням виду патології, провідних обмежень життєдіяльності, ступеня тяжкості порушень, віку пацієнтів
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18.

Type of document : Magazine article
Edition cipher :
Author(s) : Гладчук І. З., Рожковська Н. М., Каштальян Н. М.
Title : Роль імуноцитохімічних біомаркерів у діагностиці передракових захворювань шийки матки
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 80-87 (Cipher МУ10/2021/26/2)
Notes : Бібліогр. в кінці ст.
MeSH-main: ШЕЙКИ МАТКИ ДИСПЛАЗИЯ -- UTERINE CERVICAL DYSPLASIA
ЦЕРВИКАЛЬНАЯ ИНТРАЭПИТЕЛИАЛЬНАЯ НЕОПЛАЗИЯ -- CERVICAL INTRAEPITHELIAL NEOPLASIA
ИММУНОГИСТОХИМИЯ -- IMMUNOHISTOCHEMISTRY
БИОМАРКЕРЫ ФАРМАКОЛОГИЧЕСКИЕ -- BIOMARKERS, PHARMACOLOGICAL
Annotation: Незважаючи на те, що цитологічний скринінг ефективно знижує частоту випадків раку шийки матки, передракові захворювання шийки матки – дисплазії, або цервікальні інтраепітеліальні неоплазії (ЦІН), асоційовані з ураженням вірусом папіломи людини (ВПЛ) високого онкогенного ризику, продовжують представляти значний тягар для систем охорони здоров’я
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19.

Type of document : Magazine article
Edition cipher :
Author(s) : Худяков О. Є., Колдунов В. В., Клопоцький Г. А., Козлова Ю. В., Сілкіна Ю. В., Трясак Н. С., Хмель С. І., Ляліна А. Ю.
Title : Доктор медичних наук, професор, заслужений діяч науки і техніки України Сукманський Олег Іванович : (до 90-річчя від дня народження)
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 208-209 (Cipher МУ10/2021/26/2)
MeSH-main: ПАТОФИЗИОЛОГИЯ -- PHYSIOPATHOLOGY
НАУКА -- SCIENCE
ЮБИЛЕИ И ДРУГИЕ ВАЖНЫЕ СОБЫТИЯ -- ANNIVERSARIES AND SPECIAL EVENTS
ЖУРНАЛЬНАЯ СТАТЬЯ -- JOURNAL ARTICLE
Annotation: У січні цього року відсвяткував ювілей доктор медичних наук, професор, заслужений діяч науки і техніки України Олег Іванович Сукманський
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20.

Type of document : Magazine article
Edition cipher :
Author(s) : Яременко О. Б., Добрянський Д. В., Тарченко І. П., Меліксетян А. В., Федьков Д. Л.
Title : Досвід впровадження новітнього інтерактивного формату проведення лекційних занять на клінічних кафедрах і ставлення до них студентів
Place of publication : Медичні перспективи. - Д., 2021. - Т. 26, № 2. - С. 45-51 (Cipher МУ10/2021/26/2)
Notes : Бібліогр. в кінці ст.
MeSH-main: ОБРАЗОВАНИЕ МЕДИЦИНСКОЕ -- EDUCATION, MEDICAL
ОБРАЗОВАНИЯ ТЕХНОЛОГИЯ -- EDUCATIONAL TECHNOLOGY
ИНТЕРАКТИВНЫЕ ОБУЧАЮЩИЕ СИСТЕМЫ -- INTERACTIVE TUTORIAL
ПРОБЛЕМ РЕШЕНИЕ -- PROBLEM SOLVING
Annotation: Сучасна модель освіти вимагає від викладача переходу на нові методи навчання. Преподаватель перестає бути основним джерелом інформації, а перетворюється в організатора освітньої діяльності і повинен реалізовувати компетентнісний підхід у навчанні. З цією метою в Національному медичному університеті імені А.А. Богомольца внедряются новіші навчальні методики і змінюється формат проведення лекційних занять. Зміна формату лекцій у медичному вузі і, зокрема, використання сучасних лекційних навчальних технологій є важливою умовою підвищення якості підготовки майбутніх лікарів. Как показывает опыт Национального медицинского университета имени А.А. Богомольця, вони дозволяють перетворити традиційні лекції на інтерактивні заняття з підвищеною зацікавленістю в них студентів, забезпечити більш активне сприйняття матеріалу, в тому числі із-за можливості діалогу лектора зі студентами. В статті наведені результати опитувань 387 студентів, які були проведені на кафедрі внутрішньої медицини №3, а також узагальнена інформація по Національному медичному університету імені А.А. Богомольця за оцінками студентів зміни формату лекційних занять і впровадження нових методів навчання. Згідно з результатами анкетування, більшість студентів довільні якості оновленого формату лекцій на кафедрах терапевтичного профілю. Окремо проведено аналіз основних характеристик лекцій, на які необхідно звернути увагу викладачам для підвищення якості лекційних занять. На думку студентів, кращими характеристиками лекцій є актуальність, доступність матеріалу, структурованість і лаконізм, інформативність, інтерактивність, використання відеоматеріалів, практична спрямованість матеріалу, достатня кількість візуальних матеріалів, можливість вести діалог з лектором. Студенти вважають, що традиційний контроль за відвідуванням нецелесоподібний, більшість респондентів були сторонниками вільного відвідування лекцій
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