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Total number of found documents : 4
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1.
Cipher: ВУ18/2018/3
   Journal
Вісник фармації
2018year № 3
Contents:
До 80-річчя з дня народження Лауреата Державної премії України в галузі науки і техніки, Заслуженого діяча науки і техніки України, заслуженого винахідника СРСР, академіка Української АН, доктора фармацевтичних наук, заслуженого професора НФаУ Тихонова Олександра Івановича. - С.3-4
Syumka, Y. I. The synthesis of mono-and bis-derivatives of spiro-2-oxindole[3,3’]pyrrole and the study of their antioxidant and anti-inflammatory activities / Y. I. Syumka [et al.]. - С.5-13
Other authors: Kravchenko A. B., Chernykh V. P., Shemchuk L. A.
Sydora, N. V. The study of the carbohydrate composition of hawthorn fruits / N. V. Sydora, A. M. Kovaleva, V. K. Iakovenko. - С.14-18
Shynkovenko, I. L. Phenolic compounds of the liquid extract from cleavers herb (Galium aparine L.) / I. L. Shynkovenko [et al.]. - С.19-24
Other authors: Ilyina T. V., Kovalyova A. M., Goryacha O. V., Golembiovska O. I., Shemchuk N. S., Komissarenko A. М.
Hordiei, K. R. The study on the elemental composition of the feverfew herb (Tanacetum parthenium (L.) Schultz bip.) / K. R. Hordiei, T. M. Gontova, M. Y. Zolotaikina. - С.25-29
Polischuk, I. M. The study of phenolic compounds and the antimicrobial action of the alcoholic extract from the cake of the red raspberry fruit / I. M. Polischuk [et al.]. - С.30-33
Other authors: Koshovyi O. M., Osolodchenko T. P., Komissarenko M. A.
Romanenko, Ye. A. The study of the chemical composition of the components of the motherwort herb / Ye. A. Romanenko [et al.]. - С.34-38
Other authors: Koshovyi O. M., Komissarenko A. M., Golembiovska O. I., Gladyish Yu. I.
Rybachuk, V. D. The choice of the quantitative composition of excipients when creating the natural zeolite paste / V. D. Rybachuk. - С.39-43
Nemchenko, A. S. The study of the state of pharmaceutical provision for patients with cardiovascular diseases using ABC- and VEN-analyses / A. S. Nemchenko, V. N. Nazarkina, Yu. Ye. Kurylenko. - С.44-48
Germanyuk, T. A. The study of the effectiveness of the combined therapy of diabetes mellitus based on the pharmacoeconomic analysis in Ukraine / T. A. Germanyuk, T. I. Ivko, L. A. Bobrytska. - С.49-53
Volkovoy, V. A. The study of the wound healing effect of ointment from the meal of black alder leaves (Alnus Glutinosa) on the model of planar wounds / V. A. Volkovoy [et al.]. - С.54-58
Other authors: Derkach N. V., Bahlai T. O., Yeromenko O. D., Karabut L. V.
Drachuk, V. M. The effect of derivatives of sulfur-containing amino acids (ademetionine, taurine and glutathione) on survival of animals with acute kidney injury of various genesis / V. M. Drachuk [et al.]. - С.59-63
Other authors: Zamorskii I. I., Shchudrova T. S., Goroshko O. M.
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2.


    Rybachuk, V. D.
    The choice of the quantitative composition of excipients when creating the natural zeolite paste [Text] / V. D. Rybachuk // Вісн. фармації. - 2018. - № 3. - С. 39-43


MeSH-main:
ТЕХНОЛОГИЯ ФАРМАЦЕВТИЧЕСКАЯ -- TECHNOLOGY, PHARMACEUTICAL (методы)
МАЗИ -- OINTMENTS
ЦЕОЛИТЫ -- ZEOLITES
ФАРМАЦЕВТИЧЕСКИЕ СРЕДСТВА ВСПОМОГАТЕЛЬНЫЕ -- PHARMACEUTIC AIDS
КРЕМНИЯ ДИОКСИД -- SILICON DIOXIDE
Annotation: The properties of pastes depend on a number of factors, the most important of them are the concentration of the solid phase and the nature of the dispersion medium. Aim. To study the effect of the amounts of active substances and excipients on the pharmacotechnological properties of a natural zeolite paste (clinoptilolite) and to optimize the composition of the finished dosage form. Materials and methods. The objects of the study were model compositions of pastes containing the active substance – natural zeolite powder (clinoptilolite) in the concentrations of 20-30 %, a thickener – silicon dioxide in the concentrations of 6.0-8.0 %, and a plasticizer – glycerol in the concentrations of 6.0-8.0 %. Samples of pastes also contained flavoring agents – sorbitol and apple flavoring of 3 % each, and 0.02 % of a preservative – sorbic acid. To select the pharmaceutical factors significantly affecting the study object the fractional factorial experiment 23 was used with equal duplication of experiments. Three quantitative factors were studied. The responses were consistency of the paste, effective viscosity at the shear rate Dr = 5.0 s-1, the thixotropic coefficient and the adsorption activity in relation to methylene blue. The relationship between factors and responses was expressed and interpreted using the regression equations. Results and discussion. It has been determined that the samples studied belong to the thixotropically structured pseudoplastic systems with the structure of the coagulation type. It has been proven that natural zeolite (clinoptilolite) together with silicon dioxide has a structuring effect on the disperse system and the adsorption activity of the paste as a whole; the following composition is optimal (g): natural zeolite (clinoptilolite) 25.0; silicon dioxide 7.0; glycerol 5.0; sorbic acid 0.02; sorbitol 3.0; apple flavor 3.0; purified water 56.98. Conclusions. The studies on the choice of the quantitative content of excipients for obtaining the natural zeolite paste have been conducted; the optimal composition of active substances and excipients has been proposed.
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3.
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Cipher: ВУ18/2018/4
   Journal
Вісник фармації
2018year № 4
Contents:
Grygoriv, G. V. The synthesis of 2-amino-4-aryl-4H-pyrano[3,2-c][1,2] benzoxathiine-3-carbonitrile 5,5-dioxides and the study of their effect on the blood coagulation process / G. V. Grygoriv [et al.]. - С.3-8
Other authors: Legа D. A., Shemchuk L. M., Maloshtan L. M., Kalenichenko G. S., Chernykh V. P., Shemchuk L. A.
Kovalev, V. M. The study of the elemental composition of Iris hungarica and varieties of irises / V. M. Kovalev [et al.]. - С.9-15
Other authors: Krechun A. V., Mykhailenko O. O., Gryshyna O. V.
Shynkovenko, I. L. Saponins of the extracts of Galium aparine and Galium verum / I. L. Shynkovenko [et al.]. - С.16-23
Other authors: Ilyina T. V., Kovalyova A. M., Goryacha O. V., Golembiovska O. I., Koshovyi O. M.
Polishchuk, I. M. The study of saponins of the raspberry cake alcoholic extract by HPLC / I. M. Polishchuk [et al.]. - С.24-27
Other authors: Komisarenko M. A., Golik M. Yu., Upyr T. V.
Bilous, S. B. The studies on the pharmaceutical development of dosage forms with silver and gold nanoparticles for use in dentistry and surgery / S. B. Bilous [et al.]. - С.28-36
Other authors: Rieznichenko L. S., Dybkova S. M., Rybachuk A. V., Kalyniuk T. H.
Rybachuk, V. D. The choice of fillers when creating natural zeolite tablets by the wet granulation method / V. D. Rybachuk. - С.37-42
Olkhovska, A. B. The conceptual bases of implementation of the controlling system of marketing communication management in pharmaceutical organizations / A. B. Olkhovska, V. V. Malyi. - С.43-51
Yakovenko, O. V. The marketing research of drugs for prevention and treatment of stress conditions at the pharmaceutical market of Ukraine / O. V. Yakovenko, O. A. Ruban, V. V. Hrynenko. - С.52-56
Zaychenko, G. V. Experimental study of the cream with cerium dioxide nanoparticles on the model of photodynamic injury in guinea pigs / G. V. Zaychenko, O. A. Pokotylo. - С.57-62
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4.


    Rybachuk, V. D.
    The choice of fillers when creating natural zeolite tablets by the wet granulation method [Text] / V. D. Rybachuk // Вісн. фармації. - 2018. - № 4. - P37-42


MeSH-main:
ТЕХНОЛОГИЯ ФАРМАЦЕВТИЧЕСКАЯ -- TECHNOLOGY, PHARMACEUTICAL (методы)
ТАБЛЕТКИ -- TABLETS
ЦЕОЛИТЫ -- ZEOLITES

ЛАКТОЗА -- LACTOSE
ЦЕЛЛЮЛОЗА -- CELLULOSE
Annotation: Tablets are one of the most popular among all pharmaceutical dosage forms. Properties of tablets depend on a number of factors; the content of excipients is the most important of them. Among the complex of excipients of different functional orientation fillers, which can significantly affect the technological properties of tablets, in particular, hardness and friability of tablets, occupy a special place
The studies on selection of the qualitative composition of fillers for creation of natural zeolite tablets by pressing with the preliminary wet granulation have been performed, and the optimal composition of fillers has been proposed to provide the production of tablets which properties correspond to the current requirements of the SPhU
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