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Total number of found documents : 6
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1.
Cipher: ВУ18/2016/3
   Journal

Вісник фармації
2016year № 3
Contents:
Vlasov, S. V. Synthesis, the anti-inflammatory and antimicrobial activity of 6-(1H-benzimidazol-2-yl)-5-methyl-4-(alkylthio)thienо[2,3-d] pyrimidines / S. V. Vlasov, V. P. Chernykh. - С.9-16
Romanenko, M. I. The synthesis, physicochemical and biological properties of 8-amino-7-(2-hydroxy-2-phenylethyl)-3-methylxanthines / M. I. Romanenko [et al.]. - С.17-21
Other authors: Ivanphenko D. G., Nazarenko M. V., Diachkov M. V., Kamyshnyi O. M., Polishchuk N. M.
Suleimanov, T. A. Development and determination of validation parameters for the HPLC method of thymol quantification in “Kalinol plus” syrup / T. A. Suleimanov, E. Z. Balaeva, E. Yu. Akhmedov. - С.22-27
Kyslychenko, V. S. The anatomical study of shepherd’s purse herb / V. S. Kyslychenko [et al.]. - С.28-31
Other authors: Kuznietsova V. Yu., Kolisnyk Yu. S., Sushchuk N. A.
Upyr, T. V. The study of the chemical composition and the pharmacological activity of the polysaccharide complex obtained from Ledum palustre / T. V. Upyr [et al.]. - С.32-35
Other authors: Tolmachova K. S., Koshovyi O. M., Komisarenko A. M., Kireyev I. V.
Komisarenko, M. A. The composition of volatile substances of cowberry leaves / M. A. Komisarenko. - С.36-38
Lenchyk, L. V. Development of the composition of tablets with the extract of bird cherry and their standardisation / L. V. Lenchyk [et al.]. - С.39-42
Other authors: Sichkar A. A., Gladukh Ye. V., Kyslychenko V. S.
Kudrik, B. T. Development of the composition and technology of the capsulated drug based on bee bread and honey powder. Report 2. The study of pharmacotechnological properties of the mixtures of active pharmaceutikal ingredients with excipients of “Api-immuno-vit” capsules / B. T. Kudrik, O. I. Tikhonov, O. S. Shpychak. - С.43-48
Omelchenko, I. O. Substantiation of the choice of excipients of “Corvalol” in the form of sublingual tablets / I. O. Omelchenko, T. G. Yamykh, H. I. Borshchevsky. - С.49-50
Strus, O. Ye. The studies on development of the composition of masks with the sapropel paste / O. Ye. Strus, O. G. Geyderikh, L. F. Silaeva. - С.51-53
Shmal’ko, O. O. The study on development of the technology of the syrup with the hepatotropic and choleretic action / O. O. Shmal’ko [и др.] ; O. O. Shmal’ko [et al.]. - С.54-56
Other authors: Vyshnevs’ka L. I., Piskovats’kiy Yu. G., Mehalins’kiy V. A.
Balynska, M. V. The expert evaluation of drugs as a basic factor for development of the socioeconomic lists recommended for treating enteritis of the viral origin in children / M. V. Balynska. - С.57-60
Lega, D. O. Antimicrobial, anti-inflammatory and analgesic activities of 2-amino-6-ethyl-4,6-dihydropyrano[3,2-c][2,1]benzothiazine 5,5-dioxides and triethylammonium 3-[1-(4-hydroxy-1-ethyl-2,2-dioxido-1H-2,1-benzothiazin-3-yl)-3-(het)arylmethyl]-1-ethyl-1H-2,1-benzothiazin-4-olat 2,2-dioxides / D. O. Lega [et al.]. - С.61-69
Other authors: Filimonova N. I., Zupanets I. A., Shebeko S. K., Chernykh V. P., Shemchuk L. A.
Derkach, N. M. The study of the acute and chronic toxicity of the drug “Decasan” / N. M. Derkach [et al.]. - С.70-75
Other authors: ShtrygoI’ S. Yu., Laryanovska Yu. B., Grashchenkova S. A.
Bulyga, L. The histological study of the effect of gels with silver nanoparticles and glucosamine on purulent wound healing / L. Bulyga, Ya. Butko, Yu. Laryanovska. - С.76-80
До 75-річчя заслуженого діяча науки і техніки України, доктора фармацевтичних наук, професора Ковальова Володимира Миколайовича. - С.81
До 65-річчя доктора фармацевтичних наук, професора Ковальової Алли Михайлівни. - С.82
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2.


    Vlasov, S. V.
    Synthesis, the anti-inflammatory and antimicrobial activity of 6-(1H-benzimidazol-2-yl)-5-methyl-4-(alkylthio)thienо[2,3-d] pyrimidines [Text] / S. V. Vlasov, V. P. Chernykh // Вісн. фармації. - 2016. - № 3. - P9-16


MeSH-main:
БЕНЗИМИДАЗОЛЫ -- BENZIMIDAZOLES (химический синтез)
ПИРИМИДИНЫ -- PYRIMIDINES (химический синтез)
СТРУКТУРА-АКТИВНОСТЬ, ВЗАИМОСВЯЗЬ -- STRUCTURE-ACTIVITY RELATIONSHIP
ПРОТИВОВОСПАЛИТЕЛЬНЫЕ СРЕДСТВА НЕСТЕРОИДНЫЕ -- ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL (химический синтез)
АНТИБАКТЕРИАЛЬНЫЕ СРЕДСТВА -- ANTI-BACTERIAL AGENTS (химический синтез)
Additional Access Points:
Chernykh, V. P.

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3.
Cipher: ВУ18/2016/4
   Journal

Вісник фармації
2016year № 4
Contents:
Determination of the content of benzocaine and penicillin-G-procaine in combined finished dosage forms using tropaeolin O azo dye. - С.3-8
Other authors: Smolinska M. Ya., Kotsiumbas I. Ya., Teslyar G. Yu., Yurkevych M. V.
Blazheyevskiy, M. The quantitative determination of hydrogen peroxide by voltammetry on the carbositall electrode / M. Blazheyevskiy, O. Mozgova. - С.9-13
Grytsan, L. D. Some applications of physicochemical analysis in pharmacy / L. D. Grytsan. - С.14-16
The synthesis and the antimicrobial activity of the substituted arylamides of 3-arylmethyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-7-carboxylic acids. - С.17-21
Other authors: Krolenko K. Yu., Vlasov S. V., Vlasova O. D., Zhuravel I. O.
The use of analytical methods for quality control of promising active pharmaceutical ingredients among derivatives of 4-oxo-quinoline-3-propanoic acids. - С.22-30
Other authors: Zubkov V. O., Ruschak N. I., Suleiman M. M., Devyatkina A. O., Gritsenko I. S.
Stremoukhov, O. O. The study of fatty and organic acids of Vaccinium uliginosum leaves / O. O. Stremoukhov, O. M. Koshovyi, O. I. Zalyubovs’ka. - С.31-33
Stadnichenko, O. V. The study of the lipid membrane charge effect when creating liposomes with oxaliplatin / O. V. Stadnichenko, Yu. M. Krasnopolsky, T. G. Yamykh. - С.34-37
Fedorovska, M. Development of the composition of the gel base for treating telogen effluvium / M. Fedorovska, N. PoIovko. - С.38-42
Shmalko, O. O. The study on the choice of flavours for the herbal syrup with the hepatotropic action / O. O. Shmalko, L. I. Vyshnevska, V. A. Megalinskyi. - С.43-45
Development of the original method for determination of diclofenac sodium in different drug dosage forms. - С.46-49
Other authors: Khanin V. A., Kotenko O. M., Moiseev O. O., Dorovskyy O. V.
Petravska, L. S. Assessment of the main trends of developing the market of foaming detergents in Ukraine / L. S. Petravska. - С.50-53
Zarichkova, M. V. The scientific summary of monitoring results of expenditure for social protection in the European union and Ukraine / M. V. Zarichkova. - С.54-58
Determination of toxicity of new benzilic acid derivatives. - С.59-61
Other authors: Tryshchuk N. M., Kireyev I. V., Kolisnyk S. V., Sytnik K. M.
The effect of the mixtures with biologically active substances from Fraxinus excelsior and Phlomis pungens on the resistance to hypoxia in white rats compared to the action of a-tocopherol and mexidol. - С.62-65
Other authors: Takhirov I. A., Asmetov V. Y., Suleymanov T. A., Abdulkerimova F. D., Ganiev M. M., Akhmedov E. Yu.
The anti-allergic and antihistaminic properties of hydrobromide 2-[4-(4’-chlorophenyl)-2-phenyliminothiazol-3-yl]-ethanol. - С.66-69
Other authors: Koshova O. Yu., Ieryomina H. O., Perekhoda L. O., Yeryomina Z. G.
Derkach, N. M. The antimicrobial action of decamethoxinum substance at different pH values / N. M. Derkach, Z. S. Suvorova. - С.70-75
До 60-річчя професора кафедри технології ліків Національного фармацевтичного університету, доктора фармацевтичних наук Котенка Олександра Михайловича. - С.76-77
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4.


   
    The synthesis and the antimicrobial activity of the substituted arylamides of 3-arylmethyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonane-7-carboxylic acids [Text] / K. Yu. Krolenko [et al.] // Вісн. фармації. - 2016. - № 4. - P17-21


MeSH-main:
АНТИБАКТЕРИАЛЬНЫЕ СРЕДСТВА -- ANTI-BACTERIAL AGENTS (химический синтез)
КАРБОНОВЫЕ КИСЛОТЫ -- CARBOXYLIC ACIDS (химический синтез)
ГИДАНТОИНЫ -- HYDANTOINS (химический синтез)
СТРУКТУРА-АКТИВНОСТЬ, ВЗАИМОСВЯЗЬ -- STRUCTURE-ACTIVITY RELATIONSHIP
ПИРРОЛИДИНОНЫ -- PYRROLIDINONES (химический синтез)
Additional Access Points:
Krolenko, K. Yu.
Vlasov, S. V.
Vlasova, O. D.
Zhuravel, I. O.

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5.
Cipher: ВУ18/2017/1
   Journal

Вісник фармації
2017year № 1
Contents:
The synthesis, spectral properties and the biological activity of 7-arenesulfonyl-3-arylmethyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione derivatives. - С.3-9
Other authors: Krolenko K. Yu., Vlasov S. V., Zhuravel I. O., Osolodchenko T. P.
Oproshanska, T. V. Determination of the quantitative content of the amount of organic acids and ascorbic acid in different batches of Rosa majalis and Rosa canina raw material / T. V. Oproshanska, O. P. Khvorost, L. V. Ocheredko. - С.10-13
The quantitative “structure–antibacterial activity” relationships in a series of N-substituted amino acids. - С.14-20
Other authors: Golik M. Yu., Kryskiv O. S., Komissarenko A. M., Kolisnyk O. V., Dudka K. I.
The experimental substantiation of the shelf-life of “Candidocyde” vaccine. - С.21-24
Other authors: Rybalkin M. V., Strilets O. P., Strelnikov L. S., Ivakhnenko O. L.
Substantiation of the choice of components for a combined drug used for the treatment of type 2 diabetes mellitus. - С.25-31
Other authors: Toraiev K. N., Nemchenko A. S., Tsubanova N. A., Bezchasniuk O. M., Yevsieieva L. V.
Nazarkina, V. M. Substantiation of the model of pricing for essential drugs in the context of the Health Technology Assessments / V. M. Nazarkina. - С.32-37
Kobets, M. M. The subjective assessment of causes of adverse effects of drugs in the population of Ukraine / M. M. Kobets. - С.38-42
Ivko, T. The study of the Ukrainian pharmaceutical market of laxatives / T. Ivko, T. Germanyuk, L. Bobritskaya. - С.43-49
Pharmacoepidemiological analysis of the use of antibacterial drugs in the pulmonary department of the multi-specialty hospital of the Republic of Tajikistan. - С.50-55
Other authors: Savchenkova L. V., Saidova M. N., Sanginova N. S., Jabarov I. P.
Tolochko, K. V. Analysis of the domestic pharmaceutical market of anthelmintic medicines / K. V. Tolochko, L. I. Vyshnevska. - С.56-60
The study of 2-((3-R-4-R1-4H-1,2,4-triazole-5-yl)thio) acetic acid salts as growth stimulators of winter wheat sprouts. - С.61-65
Other authors: Shcherbyna R. O., Danilchenko D. M., Khromykh N. O., Lykholat Yu. V.
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6.


   
    The synthesis, spectral properties and the biological activity of 7-arenesulfonyl-3-arylmethyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione derivatives [Text] / K. Yu. Krolenko [et al.] // Вісн. фармації. - 2017. - № 1. - P3-9


MeSH-main:
СПИРОСОЕДИНЕНИЯ -- SPIRO COMPOUNDS (химический синтез)
ГИДАНТОИНЫ -- HYDANTOINS (химический синтез)
АНТИБАКТЕРИАЛЬНЫЕ СРЕДСТВА -- ANTI-BACTERIAL AGENTS (химический синтез)
СТРУКТУРА-АКТИВНОСТЬ, ВЗАИМОСВЯЗЬ -- STRUCTURE-ACTIVITY RELATIONSHIP
Key words(unnormalized):
ТРУДЫ СОТРУДНИКОВ НФаУ
Annotation: To synthesize the series of 7-arenesulfonyl-3-arylmethyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione, to study their spectral properties and antibacterial activity. Materials and methods. The methods of organic synthesis, instrumental methods of organic compounds analysis, as well as the agar diffusion method were used. Results and discussion. By the interaction of 3-arymethyl-1,3,7-triazaspiro[4.4]nonane-2,4-diones with arenesulfonyl cholrides in the presence of triethylamine the series of 7-arenesulfonyl-3-arylmethyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione was obtained. For the compounds containing the fragments of 1-sulfonylamido-(2,4)- and 3,4-difluorobenzene the1 H-1 H coupling constants in their 1Н{19F}-NMR fluorine decoupled spectra, as well as the 19 F-19 F coupling constants in the 19F{1Н}-NMR proton decoupled spectra were measured. The antimicrobial activity screening showed that the growth of such bacterial strains as Staphylococcus aureus and Bacillus subtilis was inhibited by the compounds of the series obtained. Conclusions. It has been found that the interaction of 3-arymethyl-1,3,7-triazaspiro[4.4]nonane-2,4-diones with arenesulfonyl cholrides is an effective way for the synthesis of 7-arenesulfonyl-3-arylmethyl-1,3,7-triazaspiro[4.4]nonane-2,4-diones with the promising biological activity against the strains of gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. Among 7-renesulfonyl-3-arylmethyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione derivatives 3-(3-methylbenzyl)-7-(toluene-4-sulfonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione exhibited the highest activity
Additional Access Points:
Krolenko, K. Yu.
Vlasov, S. V.
Zhuravel, I. O.
Osolodchenko, T. P.

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