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Total number of found documents : 4
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1.
Cipher: ВУ18/2017/2
   Journal
Вісник фармації
2017year № 2
Contents:
The reactivity of propyl esters of N-[(2-oxoindolin-3-ylidene)-2-oxiacetyl]amino acids. - С.3-6
Other authors: Svechnikova O. M., Kolisnyk S. V., Vinnyk O. F., Kolisnyk O. V.
Determination of related impurities in glimepiride tablets by the HPLC method. - С.7-12
Other authors: Savina N. O., Ocherethyana N. M., Britsun V. M., Ostanina N. V.
Tomarovska, L. Yu. Development of the methods for atomoxetine identification suitable for the chemical and toxicological analysis / L. Yu. Tomarovska, S. V. Baiurka, S. A. Karpushyna. - С.13-20
Comparison of chromatographic methods of analysis in a thin layer of the sorbent for identification of famotidine in tablets. - С.21-24
Other authors: Myhal A. V., Marksa M., Golovchenko O. S., Georgiyants V. A., Ivanauskas L.
The synthesis of the substituted 4-alkyl/arylsulfonyl-5-amino-3-alkylthiopyrazoles as promising pharmaceutical agents with the antifungal action. - С.25-30
Other authors: Tkachenko P. V., Tkachenko O. V., Netosova K. Yu., Borisov O. V., Zhuravel I. O.
Slipchenko, G. D. Development of the methods for spectrophotometric determination of the flavonoid concentration in solution to study bioavailability of the amount of bioactive substances in capsules containing the powder of Scutellaria baikalensis roots and rhizomes / G. D. Slipchenko, V. O. Hrudko, O. A. Ruban. - С.31-36
The study of the chemical composition and the immunomodulatory activity of polysaccharide complexes from Veronica teucrium L. - С.37-42
Other authors: Osmachko A. P., Kovaleva A. M., Ilyina T. V., Kashpur N. V., Koshovyi O. M., Komisarenko A. M.
Zujkina, S. S. The pharmacotechnological studies of the phytospecies composition for the complex therapy of mastopathy / S. S. Zujkina, L. I. Vishnevska. - С.43-47
Garkusha, M. I. Analysis of the Ukrainian employer current requirements to the pharmaceutical personnel / M. I. Garkusha, R. V. Sahaidak-Nikitiuk, G. A. Gretska. - С.48-53
Tovchiga, O. V. The effects of goutweed (Aegopodium podagraria L.) preparations on glycemia in intact rats and against the background of metformin / O. V. Tovchiga. - С.54-62
Tryschuk, N. M. The effect of benzilic acid derivatives on the pain threshold using the “hot plate” test / N. M. Tryschuk [та ін.]. - С.63-66
Other authors: Kireyev I. V., Kolisnyk S. V., Sytnik K. M.
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2.


    Tomarovska, L. Yu.
    Development of the methods for atomoxetine identification suitable for the chemical and toxicological analysis [Text] / L. Yu. Tomarovska, S. V. Baiurka, S. A. Karpushyna // Вісн. фармації. - 2017. - № 2. - С. 13-20


Rubrics: Атомоксетин

MeSH-main:
АНТИДЕПРЕССАНТЫ -- ANTIDEPRESSIVE AGENTS (анализ, выделение и очистка, отравления)
ТОКСИКОЛОГИЯ -- TOXICOLOGY (методы)
Annotation: The cases of acute and lethal poisonings by atomoxetine, an antidepressant, have been registered. Therefore, development of the available and reliable methods for its chemical and toxicological analysis is the topical issue. Aim. To develop the conditions for atomoxetine detection in the presence of a number of its pharmacological and structural analogs when performing the general TLC-screening and identification of the antidepressant by UV spectrophotometry. Materials and methods. Chromatographic mobility of antidepressants in thin sorbent layers was studied in 11 mobile phases, including those recommended by TIAFT, using five types of chromatographic plates. A number of chromogenic reagents was used for visualization. The UV-spectrum of atomoxetine was studied in 0.1 Mol • L-1 solution of hydrochloric acid. Results and discussion. Chromatographic systems with the low correlation of Rf values for atomoxetine that make them suitable for the general TLC-screening have been found. The UV spectrum of atomoxetine in the acid solution had light absorption maxima at wavelengths of 270 (ε = 1300; A11 = 45) and 277 nm. Conclusions. A combined use of three mobile phases: methanol – 25 % ammonia solution (100 : 1.5), cyclohexane – toluene – diethylamine (75 : 15 : 10), and toluene – acetone – 25 % ammonia solution (45 : 45 : 7.5 : 2.5) provides a reliable atomoxetine detection in the presence of a number of its pharmacological and structural analogs when performing the general TLC-screening. The presence of specific light absorption in the UV region of the spectrum for atomoxetine makes the UV spectrophotometry method suitable for identification of the antidepressant in toxicological studies metry method suitable for identification of the antidepressant in toxicological studies
Additional Access Points:
Baiurka, S. V.
Karpushyna, S. A.

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3.
Cipher: ВУ18/2017/4
   Journal
Вісник фармації
2017year № 4
Contents:
The use of the HPLC method for the quantitative determination of cetylpyridinium hexafluorosilicate in a dental gel. - С.3-9
Other authors: Anisimov V. Yu. , Gelmboldt V. O., Gubar S. M., Myhal A. V., Bevz N. Yu., Georgiyants V. A.
Serdiukova, Yu. Yu. Development of a novel kinetic spectrophotometric method for the quantitative determination of Cefuroxime using Caro’s acid / Yu. Yu. Serdiukova, S. G. Leonova, Yu. S. Kolisnyk. - С.10-14
Tomarovska, L. Yu. Development of the UV-spectrophotometric and extraction-spectrophotometric methods of the atomoxetine quantitative determination suitable for the chemical and toxicological analysis / L. Yu. Tomarovska, S. V. Baiurka, S. A. Karpushyna. - С.15-19
The synthesis of 3,5-dibromo-2-chlorobenzoic acid hydrazides as potential antituberculous drugs. - С.20-24
Other authors: Alferova D. O., Gritsenko I. S., Rebryk A. O., Kobzar N. P., Altukhov O. O., Shapovalova O. V., Kaliuzhnaia O. S., Suleiman M. M.
The phytochemical profile and antibacterial activity of fluid extracts of Galium verum L. herb. - С.25-28
Other authors: Shynkovenko I. L., Ilyina T. V., Goryacha O. V., Kovalyova A. M., Osolodchenko T. Р., Komisarenko A. M.
Lyapunova, A. M. The study of o/w emulsions using the rotating viscometer method and the method of spin probes / A. M. Lyapunova, O. P. Bezugla, O. M. Lyapunov. - С.29-34
Development of the composition and technology of a soap with sapropel. - С.35-40
Other authors: Strus O. Y., Polovko N. P., Filipska A. M., Rekhletska O. V.
The general methodological approach to development of modern foam washing. - С.41-44
Other authors: Baranova I. I., Petrovska L. S., Bespalaya Yu. O., Zaika S. V.
Stadnichenko, O. V. The study of liophilization parameters in the liposomal irinotecan development / O. V. Stadnichenko, Yu. M. Krasnopolsky, T. G. Yarnykh. - С.45-49
Savchenkova, L. V. The DDD-monitoring of consumption of fluoroquinolones when treating community-acquired pneumonia in a multi-specialty hospital in the Republic of Tajikistan / L. V. Savchenkova, M. N. Saidova, N. S. Sanginova. - С.50-55
The study of hypolipidemic properties of Ginger extract on the model of type 2 diabetes induced by dexamethasone. - С.56-61
Other authors: Kononenko N. M., Chikitkina V. V., Sorokina M. V., Ostapets M. O.
The effect of the new combined cream on the protein synthetic activity of cells on the model of the thermal skin damage in rats. - С.62-66
Other authors: Kononenko N. M., Sheikhali A. M., Ostapets M. O., Loboda V. S.
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4.


    Tomarovska, L. Yu.
    Development of the UV-spectrophotometric and extraction-spectrophotometric methods of the atomoxetine quantitative determination suitable for the chemical and toxicological analysis [Text] / L. Yu. Tomarovska, S. V. Baiurka, S. A. Karpushyna // Вісн. фармації. - 2017. - № 4. - С. 15-19


Rubrics: Атомоксетин

MeSH-main:
АНТИДЕПРЕССАНТЫ -- ANTIDEPRESSIVE AGENTS (анализ, выделение и очистка, отравления)
СУДЕБНАЯ ТОКСИКОЛОГИЯ -- FORENSIC TOXICOLOGY (методы, стандарты)
СПЕКТРОФОТОМЕТРИЯ УЛЬТРАФИОЛЕТОВАЯ -- SPECTROPHOTOMETRY, ULTRAVIOLET (использование, методы, стандарты)
Annotation: The acute and lethal antidepressant poisonings have the tendency to grow, therefore, development of the methods for its chemical and toxicological analysis is a topical issue
Кількість гострих та летальних отруєнь лікарськими препаратами антидепресивної дії має тенденцію до зростання, що робить актуальним розробку методів їх хіміко-токсикологічного аналізу
Additional Access Points:
Baiurka, S. V.
Karpushyna, S. A.

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