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1.


    Volotovska, N. V.
    Study of morphological changes in the kidney during modeling of ischemic-reperfusion injuries of the limb and massive blood loss [Текст] / N. V. Volotovska // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 5-10. - Bibliogr. at the end of the art.


MeSH-головна:
БОЛЕЗНЬ, МОДЕЛИ НА ЖИВОТНЫХ -- DISEASE MODELS, ANIMAL
РЕПЕРФУЗИОННОЕ ПОВРЕЖДЕНИЕ -- REPERFUSION INJURY (патофизиология, этиология)
КОНЕЧНОСТИ НИЖНЕЙ ТРАВМЫ -- LEG INJURIES (осложнения, патофизиология, этиология)
МОРФОЛОГИЧЕСКИЕ И МИКРОСКОПИЧЕСКИЕ ПОКАЗАТЕЛИ -- MORPHOLOGICAL AND MICROSCOPIC FINDINGS
ФОТОГРАФИЧЕСКИЕ СНИМКИ -- PHOTOGRAPHS
КРОВИ ПОТЕРЯ -- EXSANGUINATION (осложнения, патофизиология, этиология)
Анотація: The article presents the features of morphological disorders of liver tissue on the background of limb ischemia-reperfusion and massive blood loss. The aim of the work was to establish the presence of structural changes and the severity of morphological disorders of internal organs, remote from the primary place of ischemia-reperfusion during modeling the pathological process. The experiment was performed on 33 adult nonlinear white rats weighing 200-250 g, which were on the standard vivarium diet. Experimental animals were simulated with ischemic-reperfusion syndrome of the lower extremity and massive blood loss. Collection of materials was performed 1 h after intervention or release from the tourniquet and on the 1st, 3rd, 7th and 14th days. All interventions were performed under thiopental-sodium anesthesia (40 mg/kg body weight). Mostly structural violations were expressed as disturbance of blood supply of little and middle caliber blood vessels and also in initial dystrophic changes. During comparison of groups, depending on the severity, it was shown that both the isolated use of a tourniquet and massive blood loss had long-term, systemic consequences, however, more expressed in EG-2; single vascular glomeruli were shrunked, endothelial cells of arterioles were slightly damaged. On the 7th and 14th days changes in the structure of EG-1 were mostly absent, although in EG-2 the epitheliocytes of the outer layer of the capsule remained flattened, retained full blood vessels of the venous bed in the interstitium, and the vast majority of epitheliocytes of the excretory tubules were at different stages of hydropic dystrophy with partly desquamation of the epithelium in the gaps of the tubules. Also, the basal membranes of the tubules were not completely visualized, which indicates deep damage in the structures caused by acute ischemia as a result of bleeding. Thus, as combat trauma (blood loss) is in itself a life-threatening factor, the use of a tourniquet due to the development of ischemic-reperfusion process can complicate the course of the primary affection. Knowledge of the periodization of traumatic disease on the background of this pathology is important for the development of sanogenic effects in order to minimize this pathogenic facto
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2.


   
    Comparative assessment of renal function by cystatin С level in patients with hypertension and extrasystole [Текст] / A. V. Ivankova [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 11-17. - Bibliogr. at the end of the art.


MeSH-головна:
РЕНАЛЬНАЯ НЕДОСТАТОЧНОСТЬ -- RENAL INSUFFICIENCY (диагностика, осложнения, патофизиология, этиология)
ЦИСТАТИН C -- CYSTATIN C (диагностическое применение)
АРТЕРИАЛЬНОЕ ДАВЛЕНИЕ -- ARTERIAL PRESSURE
ЭКСТРАСИСТОЛА ЖЕЛУДОЧКОВАЯ -- VENTRICULAR PREMATURE COMPLEXES (патофизиология, этиология)
ПОЧЕЧНЫХ КЛУБОЧКОВ ФИЛЬТРАЦИИ СКОРОСТЬ -- GLOMERULAR FILTRATION RATE
ТАБЛИЦЫ -- TABLES
Анотація: Although the tight connection of the cardiovascular system and the kidneys is well known, using of cystatin C (Cys-C) opens new horizons in studying early renal failure stages. The study aimed to compare the functional status of the kidneys in patients with hypertension and extrasystole to the level of Cys-C. 156 patients with stage II hypertension (EH II) were examined. 124 of them had frequent symptomatic extrasystoles (74 – of supraventricular origin and 50 – ventricular), 32 patients had no arrhythmias, and were referred to the comparison group. The control group consisted of 30 healthy people with normal blood pressure (BP). All patients underwent a complete clinical examination, blood pressure measurement, daily blood pressure monitoring, daily electrocardiogram monitoring, echocardiography, and determination of renal function (creatinine, blood electrolytes, serum cystatin C) followed by calculation of glomerular filtration rate (GFR). The level of Cys-C in patients with hypertension was significantly higher (p0.001) compared with healthy individuals. Among patients with arrhythmias, the highest level of Cys-C was noted in patients with ventricular arrhythmias. The correlation analysis showed that the level of Cys-C was higher in the presence of frequent extrasystoles (namely of ventricular origin), smoking, high blood pressure, increased systolic and pulse blood pressure, the presence of concentric left ventricular hypertrophy, dyslipidemia, increased creatinine level and decreased GFR. All three EH II patient groups had significantly lower GFR (calculated by creatinine level) (p0.001). The lowest creatinine-based GFR was revealed in patients with ventricular extrasystole. All patients with EH II had significantly lower Cys-C based GFR than the control group (p0.001). Mean Cys-C-based GFR values in patients with extrasystole were significantly lower than in patients without extrasystole (p0.03). The analysis of GFR levels depending on the extrasystole origin was provided. The lowest level of GFR was recorded in patients with ventricular extrasystole. It was significantly different from the patients with supraventricular extrasystole (p
Дод.точки доступу:
Ivankova, A. V.
Kuzminova, N. V.
Lozinsky, S. E.
Ivanov, V. P.

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3.


   
    Determination of cephalometnc parameters which usually do not change during surgical and orthodontic treatment depending on facial types according to Garson in Ukrainian young men and young women with orthognathic occlusion [Текст] / I. Yu. Drachevska [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 18-23. - Bibliogr. at the end of the art.


MeSH-головна:
ПРИКУС СБАЛАНСИРОВАННЫЙ -- DENTAL OCCLUSION, BALANCED
ЦЕФАЛОМЕТРИЯ -- CEPHALOMETRY (методы, стандарты, статистика, тенденции)
СТОМАТОЛОГИЧЕСКИЕ ОБСЛЕДОВАНИЯ -- DENTAL HEALTH SURVEYS (статистика, тенденции)
ЭСТЕТИКА В СТОМАТОЛОГИИ -- ESTHETICS, DENTAL
УКРАИНА -- UKRAINE (этнология)
МОЛОДЫЕ -- YOUNG ADULT (статистика)
ТАБЛИЦЫ -- TABLES
ФОТОГРАФИЧЕСКИЕ СНИМКИ -- PHOTOGRAPHS
Анотація: Aesthetics is one of the key elements that accompanies modern medicine, in particular, dentistry. The need for treatment not only eliminates the symptoms of the disease but also leads to the restoration or improvement of the aesthetic appearance of the person, and especially the face, gave impetus to the development of new areas of science and technology. An important step in the implementation of such treatments is experimental research to identify the norm for certain categories of the population, primarily according to sex and ethnic group. The aim of the study was to establish the characteristics of cephalometric parameters in Ukrainian young men and young women with orthognathic occlusion, which usually do not change during surgical and orthodontic treatment, depending on sex and facial types. On the basis of the clinic "Vinintermed" teleroentgenography was performed using a dental cone-beam tomograph Veraviewepocs 3D Morita (Japan). Cephalometric examination of lateral teleroentgenograms in 46 young men (aged 17 to 21 years) and 72 young women (aged 16 to 20 years) with orthognathic occlusion was done. The type of face was determined according to the morphological index of Garson. The evaluation of parameters that usually do not change during surgical and orthodontic treatment was performed in the licensed package "Statistica 6.0" using non-parametric methods of evaluation of the results. The percentile ranges of cephalometric parameters, which usually do not change during surgical and orthodontic treatment depending on the facial types of Ukrainian young men and young women with orthognathic occlusion has been established. Pronounced manifestations of sexual dimorphism of cephalometric parameters, which usually do not change during surgical and orthodontic treatment (higher values in young men) are established only for most linear dimensions (values of distances NS, Ar-Go, N-Se, N-CC, P-PTV and S-Ar) in representatives of different types of faces. Both between young men and young women with different face types, there are almost no reliable or tendencies of differences in cephalometric parameters, which usually do not change during surgical and orthodontic treatment
Дод.точки доступу:
Drachevska, I. Yu.
Dmitriev, М. O.
Perera, Clifford
Shevchenko, V. М.
Gunas, I. V.

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4.


   
    Evaluation of the effect of excess and deficiency of serum hydrogen sulfide on the condition of the vaginal wall of intact rats [Текст] / D. I. Grebeniuk [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 24-29. - Bibliogr. at the end of the art.


MeSH-головна:
БОЛЕЗНЬ, МОДЕЛИ НА ЖИВОТНЫХ -- DISEASE MODELS, ANIMAL
ВЛАГАЛИЩЕ -- VAGINA (ультраструктура)
СЕРОВОДОРОД -- HYDROGEN SULFIDE (анализ, диагностическое применение)
МОРФОЛОГИЧЕСКИЕ И МИКРОСКОПИЧЕСКИЕ ПОКАЗАТЕЛИ -- MORPHOLOGICAL AND MICROSCOPIC FINDINGS
ФОТОГРАФИЧЕСКИЕ СНИМКИ -- PHOTOGRAPHS
ТАБЛИЦЫ -- TABLES
КРОВИ СЫВОРОТКА -- SERUM (химия)
Анотація: Various pathological conditions can be characterized not only by a decrease or increase in basal levels of hydrogen sulfide in the serum, but also the levels of hydrogen sulfide can modulate the course of the pathological process. The impact of serum hydrogen sulfide on the condition of the intact vaginal wall of rats was evaluated in this study. The aim of the study was to evaluate the effect of excess and deficiency of serum hydrogen sulfide on the condition of the vaginal wall of intact rats. The study was performed on 75 female Wistar rats under 1 year of age and weighing 160.0 to 200.0 grams. All animals were divided into 6 groups: control (intact rats); experimental 1 (H2S excess); experimental 2 (H2S deficiency); experimental 3 (intravaginal administration of suppositories with clindamycin); experimental 4 (H2S excess + suppositories with clindamycin); experimental 5 (H2S deficiency + suppositories with clindamycin). The levels of serum hydrogen sulfide were studied, as well as microscopic examination of the structure of the vaginal wall and determination of the levels of TNF-α and IL-1β in tissue homogenate were performed. In experimental groups 3, 4 and 5 all studies were performed in dynamics – 10 minutes, 4, 8 and 24 hours after a single intravaginal administration of clindamycin phosphate. The data were processed using the statistical software package SPSS 20.0 for Windows. Under conditions of both hydrogen sulfide deficiency and excess, no statistically significant changes in TNF-α and IL-1β levels in the vaginal wall of intact rats were observed. Also, no changes in the histological structure of the wall were found. Similar data were demonstrated in experimental groups 3, 4 and 5. This picture is explained by the fact that hydrogen sulfide affects various parts of the inflammatory process, while reducing the production of inflammatory mediators. In intact tissues, in the absence of an inflammatory process, there is no point of application of hydrogen sulfide, and therefore no significant changes are observed. Thus, both excess and deficiency of serum hydrogen sulfide do not affect the condition of the vaginal wall of intact rats
Дод.точки доступу:
Grebeniuk, D. I.
Voloshchuk, N. I.
Taran, I. V.
Gormash, P. P.
Nazarchuk, O. A.

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5.


   
    Actual aspects of traumatic pathology among servicemen of Ukrainian Armed Forces in Joint Forces Operation [Текст] / A. М. Halushka [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 30-35. - Bibliogr. at the end of the art.


MeSH-головна:
ВОЕННАЯ МЕДИЦИНА -- MILITARY MEDICINE (методы, организация и управление, статистика, тенденции)
ВОЕННОСЛУЖАЩИЕ -- MILITARY PERSONNEL (статистика)
РАНЫ И ТРАВМЫ -- WOUNDS AND INJURIES (классификация, патофизиология, этиология)
МЕДИЦИНСКОЙ ПОМОЩИ ПОКАЗАТЕЛИ КАЧЕСТВА -- QUALITY INDICATORS, HEALTH CARE (использование, организация и управление, тенденции)
ТАБЛИЦЫ -- TABLES
Анотація: The use of these traditional peacetime methodological approaches to accounting and analysis of non-combat injuries has led to an underestimation of its high level in the planning of inpatient care for servicemen of the Armed Forces of Ukraine in the area of the Joint Forces operation (anti-terrorist operation). The purpose of the study is a general assessment of the place of combat and non-combat injuries (including poisoning) in the structure of cases of hospitalization of servicemen of the Armed Forces of Ukraine in the area of the Joint Forces operation and anti-terrorist operation. Statistical mathematical processing was performed using computer programs Microsoft Excel and STATISTICA (version 6, StatSoft, Inc.). Based on annual medical reports on 3/med form, the ICD-10 structure of Ukrainian Armed Forces servicemen treated in MTF located in area of Joint Forces Operation for 2015-2020 has been presented. Ranks of disease classes have been calculated. Based on medical reports according Temporary instruction on codification of battle injures, non-battle trauma and diseases in Ukrainian Armed Forces, the structure of casualties admissions to MTF have been pointed out. The leading places in structure of treated servicemen belongs to patients with diagnoses on XIX class of ICD-10 (1st place for 2015-2019, 2nd place in 2020) that was stipulated by relative high levels of non-battle trauma in troops on the East of Ukraine. The comparison of structure of servicemen treated in MTF located in and out area of Joint Forces Operation as well as with structure of adult population (over 18 years old) treated in civil hospitals has been conducted. Prevalence of traumatic pathology levels among patients treated in MTF located in area of Joint Forces Operation in comparison with others treatment facilities data has been revealed. For 2015-2020 the shares of trauma and poison cases in structure of treated servicemen in MTF located in area of Joint Forces Operation significantly decreased that was connected with gradual lowing of battle actions intensity and non-battle trauma level. Based on result of research the necessity to improve curative and diagnostic base of military treatment facilities in area of Joint task operation as well as medical report and non-battle trauma prevention systems has been concluded
Дод.точки доступу:
Halushka, A. М.
Khalik, S. V.
Rychka, О. V.
Lopin, Ye. B.

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6.


    Malchenko, О. V.
    Investigation of 4-methyl-2 2-dioxo-1h-2Ae.1-benzothiazine- 3-carboxamide derivative influence on the biochemical markers of gastric mucosa in rats [Текст] / О. V. Malchenko, N. I. Voloschuk, N. O. Pentiuk // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 36-40. - Bibliogr. at the end of the art.


MeSH-головна:
БОЛЕЗНЬ, МОДЕЛИ НА ЖИВОТНЫХ -- DISEASE MODELS, ANIMAL
ПРОТИВОВОСПАЛИТЕЛЬНЫЕ СРЕДСТВА НЕСТЕРОИДНЫЕ -- ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL (анализ, токсичность)
ПРОЛЕКАРСТВА -- PRODRUGS (анализ, терапевтическое применение, фармакология)
ПОБОЧНЫЕ ЭФФЕКТЫ И НЕБЛАГОПРИЯТНЫЕ РЕАКЦИИ, СВЯЗАННЫЕ С ЛЕКАРСТВАМИ -- DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS (этиология)
ЛЕКАРСТВ ОЦЕНКА ДОКЛИНИЧЕСКАЯ -- DRUG EVALUATION, PRECLINICAL (методы, тенденции)
ЖЕЛУДКА СЛИЗИСТАЯ -- GASTRIC MUCOSA (действие лекарственных препаратов)
ТАБЛИЦЫ -- TABLES
Анотація: Non-steroidal anti-inflammatory drugs occupy a leading position in the pharmaceutical market, but their class-specific side effect (ulcerogenic action) significantly limits their widespread use. The N-(4-methoxybenzyl)-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide derivative (compound NI-9) showed a pronounced analgesic effect in various models of pain syndromes. The aim of the study was to determine the effect of a new original derivative of 4-methyl-2.2-dixo-1H-2λ6,1-benzothiazine-3-carboxylic acid on the macroscopic state and biochemical parameters of the gastric mucosa of rats. The study was performed on 51 male Wistar rats. Compound NI-9 and the reference drug meloxicam were administered intragastrically once daily for 28 days at doses of 3 and 5 mg/kg, corresponding to their ED50 analgesic activity. Macroscopic indicators of GM damage, glycosaminoglycan content, phospholipid profile, level of MDA and CGP, as well as nitrates and nitrites and H2S were determined. The results were processed in the program STATISTICA 10.0 using non-parametric methods. The results showed that the carboxamide derivative was safer for the stomach because the ulcer index of compound NI-9 was 1.73 times lower than that of meloxicam. The damaging effect of the compound was more pronounced at the pre-epithelial and epithelial levels of GM protection, while the post-epithelial level (production of vasodilating molecules NO and H2S) was practically unaffected by this derivative, unlike meloxicam, which caused damage at all levels of protection. The obtained data supplement the data on the pharmacodynamics of the 4-methyl-2.2-dixo-1H-2λ6,1-benzothiazine-3-carboxylic acid derivative and determine the expediency of its further studies as a potential non-opioid analgesic
Дод.точки доступу:
Voloshchuk, N. I.
Pentiuk, N. O.

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7.


    Samborska, I. A.
    Changes in the histostructure of the lungs of old rats under conditions of persistent hyperhomocysteinemia [Текст] / I. A. Samborska // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 41-45. - Bibliogr. at the end of the art.


MeSH-головна:
ГОМОЦИСТЕИН -- HOMOCYSTEINE (анализ, диагностическое применение)
ЛЕГКИХ БОЛЕЗНИ ОБСТРУКТИВНЫЕ -- LUNG DISEASES, OBSTRUCTIVE (диагностика, патофизиология, этиология)
БОЛЕЗНЬ, МОДЕЛИ НА ЖИВОТНЫХ -- DISEASE MODELS, ANIMAL
ЛЕГОЧНЫЕ АЛЬВЕОЛЫ -- PULMONARY ALVEOLI (действие лекарственных препаратов, патофизиология)
ГИСТОЛОГИЧЕСКИЕ МЕТОДЫ -- HISTOLOGICAL TECHNIQUES (использование, тенденции)
Анотація: To date, homocysteine has been found to be an important biomarker of bronchopulmonary pathology, including COPD. The increase in its concentration in the blood plasma causes the start of free radical processes and the production of reactive oxygen species, which activate lipid peroxidation in lung tissue. In addition, the activation of endoplasmic reticulum stress with increasing homocysteine levels is the main reason for triggering apoptosis of alveolocytes. The aim of the research is to study the features of lungs histostructure in old rats under conditions of hyperhomocysteinemia. The experimental study was performed on 20 white nonlinear old (24-26 months) male rats. During the experiment, the animals were divided into two groups – control and experimental. Simulation of the state of persistent hyperhomocysteinemia was achieved by administering to rats of experimental group thiolactone homocysteine at a dose of 200 mg/kg body weight intragastrally for 60 days. Histological specimens were studied using an SEO CCAN light microscope and photo-documented using a Vision CCD Camera with an image output system from histological specimens. In elderly animals under conditions of experimental hyperhomocysteinemia develop severe destructive-degenerative changes in the lungs. Significant remodeling of the vascular bed, bronchi, inflammatory manifestations, enlargement of dis- and atelectasis and emphysematically altered alveoli of the respiratory lungs, violation of the alveolar walls, with the release of blood cells into the alveolar space and the formation of small diapedetic hemorrhages. The development of perivascular, peribronchial and interstitial sclerosis is characteristic
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8.


   
    Investigation of pharmacokinetics of N-(4-trifluoromethylphenyl)-4-methyl-2.2-dioxo-1H-2λ6.1-benzothiazine-3-carboxamide various crystalline modifications in vivo [Текст] / P. S. Bondarenko [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 46-51. - Bibliogr. at the end of the art.


MeSH-головна:
МОДЕЛИ НА ЖИВОТНЫХ -- MODELS, ANIMAL
ЛЕКАРСТВЕННЫЕ СРЕДСТВА МОДИФИЦИРОВАННЫЕ -- DESIGNER DRUGS (анализ, фармакокинетика)
ХИМИЯ ФАРМАЦЕВТИЧЕСКАЯ -- CHEMISTRY, PHARMACEUTICAL (методы, тенденции)
КРИСТАЛЛИЗАЦИЯ -- CRYSTALLIZATION
ПРОТИВОВОСПАЛИТЕЛЬНЫЕ СРЕДСТВА НЕСТЕРОИДНЫЕ -- ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL (анализ, фармакокинетика)
ТАБЛИЦЫ -- TABLES
ФОТОГРАФИЧЕСКИЕ СНИМКИ -- PHOTOGRAPHS
Анотація: The phenomenon of polymorphism, inherent in many biologically active substances, including drugs, is an extremely serious problem that requires close attention and comprehensive study. Various crystalline modifications of biologically active compounds, as well as excipients can dramatically change the biopharmaceutical properties and pharmacological characteristics of already known drugs. The bioactive compound N-(4-trifluoromethylphenyl)-4-methyl-2.2-dioxo-1H-2λ6.1-benzothiazine-3-carboxamide was obtained by bioisosterical substitution in the molecule of known non-steroidal anti-inflammatory drugs of the oxycam group in the form of three polymorphic modifications of the crystal. sticks (form A), plates (form B) and blocks (form C) with varying degrees of analgesic and anti-inflammatory effects. The aim of the study was to investigate the pharmacokinetic profile of these polymorphic forms of benzothiazine-3-carboxamide derivative by their oral administration in vivo. The concentration of compounds in the blood of mice was determined by HPLC and the main pharmacokinetic parameters were calculated. It was found that the polymorphic form in the form of plates (form B), in particular, having the largest surface area of crystals, has differences mainly at the stage of absorption with corresponding changes in absorption values, maximum concentration and time of its achievement, has the highest bioavailability and rapid elimination which correlates with the most optimal pharmacological and toxicological characteristics of this compound in comparison with other crystalline forms. This makes it possible to recommend the most active and safe polymorphic form of the compound (form B) for in-depth preclinical study and possible clinical trials as an analgesic and anti-inflammatory agent
Дод.точки доступу:
Bondarenko, P. S.
Voloshchuk, N. I.
Larionov, V. B.
Fedoseenko, Η. O.

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9.


   
    Correlations of basal cranial structures characteristics determined by Bjork and Jarabak methods with teleradiographic parameters of the upper and lower jaws and tooth location in young men and young women with orthognathic occlusion [Текст] / V. V. Vakhovskyi [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 52-59. - Bibliogr. at the end of the art.


MeSH-головна:
ЧЕРЕП -- SKULL (анатомия и гистология, рентгенография)
МОЛОДЫЕ -- YOUNG ADULT (физиология)
ПРИКУС СБАЛАНСИРОВАННЫЙ -- DENTAL OCCLUSION, BALANCED
УКРАИНА -- UKRAINE (этнология)
ЦЕФАЛОМЕТРИЯ -- CEPHALOMETRY (история, методы, статистика, тенденции)
ТАБЛИЦЫ -- TABLES
ЧЕЛЮСТЬ НИЖНЯЯ -- MANDIBLE (анатомия и гистология, рентгенография, рост и развитие)
Анотація: The widespread use of methods of cephalometric analysis in practical orthodontics requires the adaptation of normative indicators for members of the local ethnic group. It is also important to study the relationships between cranial and odontometric parameters to understand the effects of these components on each other. The aim of the study was to establish the peculiarities of correlations between the characteristics of basal cranial structures determined by Bjork and Jarabak methods with teleradiographic parameters of the upper and lower jaws and the location of teeth in Ukrainian young men and young women with orthognathic occlusion. Teleradiography was performed in the mode of cephalometric examination of 49 young men (aged 17 to 21 years) and 76 young women (aged 16 to 20 years) who had a physiological bite as close as possible to orthognathic. Cephalometric analysis according to modifications of Jarabak J. R. – Roth-Jarabak and Bjork A. – CFT-Bjork methods, performed using OnyxCeph³™ software, 3DPro version, Image Instruments GmbH, Germany (software license № URSQ-1799). All indicators were divided into three groups according to Dmitriev M. O. (2017): the first group included metric characteristics of the skull, which are used as basic indicators in the methods of cephalometric analysis; to the second group – dental-maxillary in which the skeleton has already been formed and which surgical methods can change the length, width, angles and positions of the upper and lower jaws; to the third group – indicators that actually characterize the position of each individual tooth relative to each other, cranial structures and the profile of the soft tissues of the face. Correlation assessment was performed in the license package "Statistica 6.0" using the non-parametric Spearman method. As a result of the conducted researches in Ukrainian young men and young women with orthognathic occlusion the peculiarities of multiple correlations of characteristics of basal cranial structures determined by CFT-Bjork and Roth-Jarabak methods with teleradiographic parameters of upper and lower jaws and tooth location were established. Both the CFT-Bjork method and the Roth-Jarabak method have more reliable correlations in both young men and young women between the first and second groups (23.3 % for young men and 50.0 % for young women for CFT-Bjork and 48.4 % for young men and 41.1% for young women according to Roth-Jarabak) than between the indicators of the first and third groups (respectively 12.8 % for young men and 7.7 % for young women for CFT-Bjork and 22.5 % for young men and 12.5 % for young women for Roth-Jarabak). The expressed manifestations of sexual dimorphism of the received correlations between the indicators defined by CFT-Bjork and Roth-Jarabak methods both on quantity and force, and in some cases on a direction of correlations are established
Дод.точки доступу:
Vakhovskyi, V. V.
Shinkaruk-Dykovytska, М. М.
Pogorila, A. V.
Likhitskyi, O. O.
Gunas, I. V.

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10.


   
    Correlations between the severity of oily skin and the emotional impact of oily skin with anthropo-somatotypological parameters of men and women with seborrheic dermatitis [Текст] / Ahmad Raed Khasawneh [та ін.] // Biomedical and Biosocial Anthropology. - 2020. - № 41. - С. 60-66. - Bibliogr. at the end of the art.


MeSH-головна:
ДЕРМАТИТ СЕБОРЕЙНЫЙ -- DERMATITIS, SEBORRHEIC (диагностика, патофизиология, профилактика и контроль, этиология)
ПОЛОВАЯ ДИФФЕРЕНЦИАЦИЯ -- SEX DIFFERENTIATION (физиология)
КОЖИ АНОМАЛИИ -- SKIN ABNORMALITIES (патофизиология, этиология)
АНТРОПОМЕТРИЯ -- ANTHROPOMETRY (методы)
ЭМОЦИЙ НЕГАТИВНЫХ ВЫРАЖЕНИЕ -- EXPRESSED EMOTION
СТАТИСТИЧЕСКАЯ ОБРАБОТКА ДАННЫХ -- DATA INTERPRETATION, STATISTICAL
ТАБЛИЦЫ -- TABLES
Анотація: The increase in the prevalence and age of seborrhea, its significant impact on the psycho-emotional sphere, social status and social adaptation of patients determines the relevance of further study of the causes of dermatosis in the key of constitutional psychodermatology, namely – the study of relationships between oily skin and emotional impact of oily skin with anthropometric indicators. The aim of the study was to analyze the correlations between Oily Skin Self Assessment Scale (OSSAS) and Oily Skin Impact Scale (OSIS) in men and women with seborrheic dermatitis with body structure and size indicators. A survey of 40 men and 40 young women with generalized fatty seborrheic dermatitis done. The OSSAS and OSIS scoring system was used to assess the severity of oily skin and the emotional impact of oily skin in seborrheic dermatitis. Anthropometric survey was carried out according to the scheme of Bunak V. V. (1941). The mathematical scheme of Carter J. and Heath B. (1990) was used to evaluate the somatotype. Matiegka J. (1921) formulas were used to calculate body weight components. In addition, the muscle component of body weight was assessed by the American Nutrition Institute. Correlation analysis was performed in the license package "Statistica 6.0" using the non-parametric Spearman’s method. As a result of the conducted researches multiple reliable and moderate unreliable correlations of OSSAS or OSIS with anthropo-somatotypological indicators of men and women of patients with generalized fatty form of seborrheic dermatitis of mild and severe course were established. The practical lack of similar correlations between OSIS and anthropo-somatotypological parameters in men and women with severe seborrheic dermatitis is noteworthy. Quantitative analysis of reliable and moderate unreliable correlations of OSSAS or OSIS with anthropo-somatotypological parameters in men and women with seborrheic dermatitis of mild and severe course showed that the vast majority of such correlations are inverse, and unreliable average correlations are often observed (except for OSSAS correlations with anthropo-somatotypological parameters in women with mild disease). It was also found that regardless of sex, most of the reliable or moderately unreliable correlations between OSSAS or OSIS and anthropo-somatotypological indicators are observed in the mild course of the disease. The obtained results of the correlation analysis expand the current understanding of the risk criteria and unfavorable prognosis of seborrheic dermatitis
Дод.точки доступу:
Khasawneh, Ahmad Raed
Dmytrenko, S. V.
Kizina, I. E.
Kyrychenko, Yu. V.
Prokopenko, S. V.

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