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1.
Шифр: ВУ18/2018/2
   Журнал

Вісник фармації
2018р. № 2
Зміст:
Kolisnyk, S. V. The reactivity of ethyl esters of 2-(benzoylamino) (1-R-2-oxoindoline-3-ylidene) acetic acids / S. V. Kolisnyk [et al.]. - С.3-7
Інші автори: Svechnikova O. M., Vinnyk O. F., Kolisnyk O. V., Altukhov O. O.
Yusifova, D. Yu. Determination of a number of indicators of “Venocoryl” ointment / D. Yu. Yusifova, T. A. Suleymanov. - С.8-11
Kovalevska, I. V. The spectrophotometric study of thioctic acid solutions to develop the method of its quantitative determination / I. V. Kovalevska, O. A. Ruban, V. O. Grud’ko. - С.12-18
Kerimov, Yu. B. The pharmacognostic study of the aerial part of Prangos ferulacea lindl. at the stage of the beginning of vegetation / Yu. B. Kerimov [et al.]. - С.19-23
Інші автори: Isaev D. I., Kerimli E. G., Akhmedov E. Yu.
Redkin, R. G. The synthesis of spiro[indole-3,1’-pyrrolo[3,4-c]pyrrole]-2,4’,6’-trione derivatives, the study of their antimicrobial activity and the molecular docking on staphylococcal dehydrosqualene synthase / R. G. Redkin, K. V. Hlebova. - С.24-35
Sydora, N. V. The technological aspects for complex processing of hawthorn fruits / N. V. Sydora, A. M. Kovalyova, V. K. Iakovenko. - С.36-40
Kriukova, A. I. The study of the technological and microbiological parameters of a dietary supplement “Osteovert” / A. I. Kriukova, I. M. Vladymyrova. - С.41-47
Nemchenko, A. S. Analysis of approaches to pharmacotherapy of patients with cardiovascular diseases according to the data of the Ukrainian and British Formularies / A. S. Nemchenko, Yu. Ye. Kurylenko. - С.48-51
Kobets, M. M. A social significance of the pharmacogenetic testing in Ukraine on the example of the CYP2B6 gene participating in the nicotine metabolism / M. M. Kobets, O. V. Filiptsova, Yu. M. Kobets. - С.52-56
Syumka, Ye. I. The study of the antimicrobial activity of ethylene-N,N’- bis(spiroindole-3,3’-pyrrolo[3,4-c]pyrrole-2a’,5a’-dihydro-2,2’,6’(1H,1’H,5’H)-trione) derivatives / Ye. I. Syumka [et al.]. - С.57-62
Інші автори: Osolodchenko T. P., Chernykh V. P., Shemchuk L. A.
Є примірники у відділах: всього 1
Вільні: 1

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2.


    Sydora, N. V.
    The technological aspects for complex processing of hawthorn fruits [Текст] / N. V. Sydora, A. M. Kovalyova, V. K. Iakovenko // Вісн. фармації. - 2018. - № 2. - С. 36-40


MeSH-головна:
БОЯРЫШНИК -- CRATAEGUS
(химия)
ТЕХНОЛОГИЯ -- TECHNOLOGY (методы)
Кл.слова (ненормовані):
КОМПЛЕКСНАЯ ПЕРЕРАБОТКА СЫРЬЯ
Анотація: Considering the shortage of the plant raw material the issue of its complex processing is relevant, and it contributes to its rational use. Aim. To develop the technology for complex processing of hawthorn fruits. Materials and methods. The lipophilic complex (LC) extraction was carried out with chloroform in the raw material-extractant ratio of 1 : 10; the phenolic complex (PhC) was prepared with the ethyl acetate-alcohol mixture in the ratio of 8 : 2; WSPC was obtained by triple extraction of the fruits meal after preparing LC and PhC with hot purified water followed by concentration and precipitation with 96 % ethyl alcohol. Results and discussion. It was found that the yield of LC in fruits of the hawthorn species studied was from 1 % to 10 %, the highest yield was determined in the fruits of C. submollis Sarg., C. succulenta Schrad. and C. densiflora Sarg. The yield of PhC was from 9 % to 18 %, C. submollis Sarg., C. mollis Sarg., C. arnoldiana Sarg. and C. canadensis Sarg. dominated. WSPC was from 15 % to 35 %, the highest yield was determined for fruits of C. submollis Sarg., C. macracantha Lodd, C. mollis Sarg., C. arnoldiana Sarg., C.succulenta Schrad. Conclusions. The technology of the complex processing of hawthorn fruits – C. submollis Sarg., C. mollis Sarg., C. arnoldiana Sarg., C. canadensis Sarg., C. oxyacantha L., C. monogyna Jack., C. sanguinea Pall., C. pentagyna Waldst. Et Kit., C. aronia (L.) Bosc, C. densiflora Sarg., C. succulenta Schrad, C. macracantha Lodd., C. flabellata (Bosc) C. Koch., C. pseudokyrtostylla Klok., C. ukrainica A. Pojark., C. ambiguae C. A. M – has been developed. As a result of complex processing of the plant raw material such complexes as LC, PhC and WSPC have been obtained
Дод.точки доступу:
Kovalyova, A. M.
Iakovenko, V. K.

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3.
Шифр: ВУ18/2018/3
   Журнал

Вісник фармації
2018р. № 3
Зміст:
До 80-річчя з дня народження Лауреата Державної премії України в галузі науки і техніки, Заслуженого діяча науки і техніки України, заслуженого винахідника СРСР, академіка Української АН, доктора фармацевтичних наук, заслуженого професора НФаУ Тихонова Олександра Івановича. - С.3-4
Syumka, Y. I. The synthesis of mono-and bis-derivatives of spiro-2-oxindole[3,3’]pyrrole and the study of their antioxidant and anti-inflammatory activities / Y. I. Syumka [et al.]. - С.5-13
Інші автори: Kravchenko A. B., Chernykh V. P., Shemchuk L. A.
Sydora, N. V. The study of the carbohydrate composition of hawthorn fruits / N. V. Sydora, A. M. Kovaleva, V. K. Iakovenko. - С.14-18
Shynkovenko, I. L. Phenolic compounds of the liquid extract from cleavers herb (Galium aparine L.) / I. L. Shynkovenko [et al.]. - С.19-24
Інші автори: Ilyina T. V., Kovalyova A. M., Goryacha O. V., Golembiovska O. I., Shemchuk N. S., Komissarenko A. М.
Hordiei, K. R. The study on the elemental composition of the feverfew herb (Tanacetum parthenium (L.) Schultz bip.) / K. R. Hordiei, T. M. Gontova, M. Y. Zolotaikina. - С.25-29
Polischuk, I. M. The study of phenolic compounds and the antimicrobial action of the alcoholic extract from the cake of the red raspberry fruit / I. M. Polischuk [et al.]. - С.30-33
Інші автори: Koshovyi O. M., Osolodchenko T. P., Komissarenko M. A.
Romanenko, Ye. A. The study of the chemical composition of the components of the motherwort herb / Ye. A. Romanenko [et al.]. - С.34-38
Інші автори: Koshovyi O. M., Komissarenko A. M., Golembiovska O. I., Gladyish Yu. I.
Rybachuk, V. D. The choice of the quantitative composition of excipients when creating the natural zeolite paste / V. D. Rybachuk. - С.39-43
Nemchenko, A. S. The study of the state of pharmaceutical provision for patients with cardiovascular diseases using ABC- and VEN-analyses / A. S. Nemchenko, V. N. Nazarkina, Yu. Ye. Kurylenko. - С.44-48
Germanyuk, T. A. The study of the effectiveness of the combined therapy of diabetes mellitus based on the pharmacoeconomic analysis in Ukraine / T. A. Germanyuk, T. I. Ivko, L. A. Bobrytska. - С.49-53
Volkovoy, V. A. The study of the wound healing effect of ointment from the meal of black alder leaves (Alnus Glutinosa) on the model of planar wounds / V. A. Volkovoy [et al.]. - С.54-58
Інші автори: Derkach N. V., Bahlai T. O., Yeromenko O. D., Karabut L. V.
Drachuk, V. M. The effect of derivatives of sulfur-containing amino acids (ademetionine, taurine and glutathione) on survival of animals with acute kidney injury of various genesis / V. M. Drachuk [et al.]. - С.59-63
Інші автори: Zamorskii I. I., Shchudrova T. S., Goroshko O. M.
Є примірники у відділах: всього 1
Вільні: 1

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4.


    Sydora, N. V.
    The study of the carbohydrate composition of hawthorn fruits [Текст] / N. V. Sydora, A. M. Kovaleva, V. K. Iakovenko // Вісн. фармації. - 2018. - № 3. - С. 14-18


MeSH-головна:
БОЯРЫШНИК -- CRATAEGUS (химия)
УГЛЕВОДЫ -- CARBOHYDRATES (анализ)
ПОЛИСАХАРИДЫ -- POLYSACCHARIDES (анализ)
Анотація: Carbohydrates, in particular monosaccharides, are necessary for the normal functioning of the human body. Therefore, the search for plant sources of available carbohydrates, such as glucose, fructose, arabinose, is relevant today. Aim. To determine the qualitative composition and the quantitative content of monosaccharides of hawthorn fruits. Materials and methods. Extraction of polysaccharides from the raw material was carried out with purified water in the ratio of the raw material – extractant of 1 : 10 and further treatment of the filtrate with 96 % ethyl alcohol. The preliminary identification of sugars was performed by paper chromatography (PC) after acid hydrolysis. The qualitative composition and the quantitative content of sugars were determined by the gas chromatography-mass spectrometry method on an Agilent 6890N/5973 inert device (Agilent Technologies, USA). The total sugars were isolated by acid hydrolysis using 2 M trifluoroacetic acid. For extraction of free sugars the mixture of methyl alcohol solution and the internal standard (the solution of sorbitol) was added to the powdered raw material. Results and discussion. As a result of chromatography (PC) with the reliable samples glucose and fructose were identified in the raw material. By the chromatography-mass spectrometry study the presence of 5 free sugars was detected, among them glucose (2.02 mg/g), fructose (2.21 mg/g) and sucrose (0.23 mg/g) were determined. After acidic hydrolysis arabinose (1.82 mg/g), xylose (3.88 mg/g), mannose (4.25 mg/g), glucose (5.57 mg/g) and galactose (1.31 mg/g) were identified. Conclusions. The composition of sugars in hawthorn fruit has been found. The highest content has been determined for fructose, glucose and mannose
Дод.точки доступу:
Kovaleva, A. M.
Iakovenko, V. K.

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