Бібліотека Вінницького національного медичного університету ім. М.І.Пирогова

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Шифр: УУ60/2019/91/2
Журнал

The Ukrainian biochemical journal [Текст]. - Виходит раз на два місяця
2019р. Т. 91 № 2 . - 138.92, р.

Зміст:
Vari, S. G. The Sisyphus Effect / S. G. Vari. - P.5. - Bibliogr. at the end of the art.
Kobylinska, L. Targeting of the pro-oxidant-antioxidant balance in vitro and in vivo by 4-thiazolidinone-based chemotherapeutics with anticancer potential / L. Kobylinska [та ін.]. - P.7-18. - Bibliogr. at the end of the art.
Інші автори: Klyuchivska O., Lesyk R., Stoika R.
Chernyshenko, V. Preparation of highly-concentrated autologous platelet-rich plasma for biomedical use / V. Chernyshenko [та ін.]. - P.19-28. - Bibliogr. at the end of the art.
Інші автори: Shteinberg K., Lugovska N., Ryzhykova M., Platonova T., Korolova D., Lugovskoy E.
Finiuk, N. S. Apoptosis induction in human leukemia cells by novel 2-amino-5-benzylthiazole derivatives / N. S. Finiuk [та ін.]. - P.29-40. - Bibliogr. at the end of the art.
Інші автори: Ivasechko I. I., Klyuchivska O. Yu., Ostapiuk Yu. V., Hreniukh V. P., Shalai Ya. R., Matiychuk V. S., Obushak M. D., Babsky A. M., Stoika R. S.
Paryzhak, S. Ya. Interaction of 4 allotropic modifications of carbon nanoparticles with living tissues / S. Ya. Paryzhak [та ін.]. - P.41-51. - Bibliogr. at the end of the art.
Інші автори: Dumych T. I., Peshkova S. M., Bila E. E., Lutsyk A. D., Barras A., Boukherroub R., Szunerits S., Bilyy R. O.
Chernyshenko, V. Blood coagulation parameters in rats with acute radiation syndrome receiving activated carbon as a preventive remedy / V. Chernyshenko [та ін.]. - P.52-64. - Bibliogr. at the end of the art.
Інші автори: Snezhkova E., Mazur M., Chernyshenko T., Platonova T., Sydorenko O., Lugovskoy E., Nikolaev V.
Young scientists conference Modern Aspects of Biochemistry and Biotechnology – 2019. - P.65-93
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Вільні: 1

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Vari, S. G.
The Sisyphus Effect [Текст] = Ефект Сізіфа / S. G. Vari // The Ukrainian Biochemical Journal. - 2019. - Т. 91, № 2. - С. 5. - Bibliogr. at the end of the art.

MeSH-головна:
ФИЗИОЛОГИЧЕСКИЕ ПРОЦЕССЫ -- PHYSIOLOGICAL PROCESSES
ГОМЕОСТАЗ -- HOMEOSTASIS
АКТИВАЦИЯ МЕТАБОЛИЧЕСКАЯ -- ACTIVATION, METABOLIC
БИОМЕДИЦИНСКИЕ ИССЛЕДОВАНИЯ -- BIOMEDICAL RESEARCH (кадры, организация и управление, тенденции)
Анотація: Scientific work for researchers, women and men equally, is an endless challenge. Determining new markers for early diagnosis of diseases, investigating the maintenance of cell and tissue homeostasis, studying metabolic regulation and dysregulation as well as intra-organ and interorgan crosstalk can be tiresome work and can sometimes seem like the punishment Zeus gave to Sisyphus. Sisyphus, the Greek mythological figure, was condemned to roll a boulder up a mountain but near the top of the mountain the boulder roll down; for eternity Sisyphus was forced to repeat this task over and over. Although scientific research can sometimes seem like this, the cleverness of scientists helps to overcome the “Sisyphus Effect”. “I leave Sisyphus at the foot of the mountain. One always finds one’s burden again. But Sisyphus teaches the higher fidelity that negates the gods and raises rocks”. Sisyphus is a symbol of self-overcoming. Sisyphus was also infamous for his deception though, which had led Zeus to punish him to roll the boulder up a hill that rolled down repeatedly, and Sisyphus had to keep trying again and again for eternity. While the vast majority of scientists are honest and work hard to achieve their research goals, some scientists are egotistical and may resort to trickery and doing things unethically. In Science the role of Sisyphus is played by the community of researchers, and to ensure that the boulder does not roll down the hill again. We researchers have to share our research results as well as repeat the published methods and research protocols again and again and these tasks can seem like “Sisyphean” work. Furthermore, in Science, the research community also plays the role of Zeus and will punish dishonesty so therefore we researchers must roll a boulder up a hill again and again and after we have proved that the published scientific work is sound, the “boulder” and the scientist will stay on top of the hill. In the Association for Regional Cooperation in the Fields of Health, Science and Technology (RECOOP HST Association) scientists equally share the burden of Zeus and Sisyphus independently of the status of their X and Y chromosomes, and I know from Albert Camus’ essay that Sisyphus is Happy. Each atom of that stone, each mineral flake of that night-filled mountain, in itself, forms a world. The struggle itself toward the heights is enough to fill a man’s heart. One must imagine Sisyphus happy
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Шифр: УУ60/2020/92/2
Журнал

The Ukrainian biochemical journal [Текст]. - Виходит раз на два місяця
2020р. Т. 92 № 2

Зміст:
Vari, S. G. Homo scientist can lead HOMO SAPIENS to the next evolutionary stage, to HOMO ingenious / S. G. Vari. - P.5-6
Korolyuk, O. Ya. Hypertriclyceridemia is associated with long-term risk of cardiovascular events and specific comorbidity in very high-risk hypertensive patients / O. Ya. Korolyuk, O. M. Radchenko. - P.8-19
Bozhenko, M. Freezing influences, the exposure of IgG glycans in sera from multiple sclerosis patients / M. Bozhenko [et al.]. - P.21-31
Інші автори: Boichuk M., Bila G., Nehrych T., Bilyy R.
Nasadyuk, C. M. Lectinocytochemical study of rat stomach mucosa under the conditions of cyclooxygenase-1/-2 blockage and pretreatment with H-GLU-ASP-GLY-OH / C. M. Nasadyuk [et al.]. - P.33-43
Інші автори: Sogomonyan E. A., Yashchenko A. M., Sklyarov A. Y.
Onopchenko, O. V. The effect of N-stearoylethanolamine on the lipid composition of the rat testes and testosterone level during the early stages of streptozotocin-induced diabetes / O. V. Onopchenko [et al.]. - P.45-59
Інші автори: Horid’ko T. M., Kosiakova H. V., Berdyshev A. G., Klimashevsky V. M., Hula N. M.
Tkachenko, O. S. Protective action of N-stearoylethanolamine on blood coagulation and arterial changes in spontaneously hypertensive rats fed cholesterol-rich diet / O. S. Tkachenko [et al.]. - P.60-71
Інші автори: Hydz Ie. A., Kosiakova H. V., Klymenko P. P., Stohnii Y. M., Didkivskyi V. A., Chernyshenko T. M., Chernyshenko V. O., Platonova T. M.
Stohnii, Y. M. Aggregation of platelets, proliferation of endothelial cells and motility of cancer cells are mediated by the Bβ1(15)-42 residue of fibrin(ogen) / Y. M. Stohnii [et al.]. - P.72-85
Інші автори: Ryzhykova M. V., Rebriev A. V., Kuchma M. D., Marunych R. Y., Chernyshenko V. O., Shablii V. A., Lypova N. M., Slominskyi O. Yu., Garmanchhuk L. V., Platonova T. M., Komisarenko S. V.
Revenko, O. Exogenous hydrogen sulfide for the treatment of mesenteric damage associated with fructose-induced malfunctions via inhibition of oxidative stress / O. Revenko [et al.]. - P.86-98
Інші автори: Zaichko N., Wallace J., Zayachkivska O.
Bila, G. Novel approach for discrimination of eosinophilic granulocytes and evaluation of their surface receptors in a multicolor fluorescent histological assessment / G. Bila [et al.]. - P.99-107
Інші автори: Schneider M., Peshkova S., Krajnik B., Besh L., Lutsyk A., Matsyura O., Bilyy R.
Kryshchyshyn, A. Synthesis and anti-leukemic activity of pyrrolidinedione-thiazolidinone hybrids / A. Kryshchyshyn [et al.]. - P.108-120
Інші автори: Kaminskyy D., Roman O., Kralovics R., Karpenko O., Lesyk R.
Hreniukh, V. P. Effects of thiazole derivatives on intracellular structure and functions in murine lymphoma cells / V. P. Hreniukh [et al.]. - P.121-131
Інші автори: Finiuk N. S., Shalai Ya. R., Manko B. O., Manko B. V., Ostapiuk Yu. V., Kulachkovskyy O. R., Obushak M. D., Stoika R. S., Babsky A. M.
Chaban, T. I. Development of effective anti-inflammatory drug candidates among novel thiazolopyridines / T. I. Chaban [et al.]. - P.132-139
Інші автори: Matiychuk V. S., Ogurtsov V. V., Chaban I. G., Nektegayev I. A.
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Vari, S. G.
Homo scientist can lead HOMO SAPIENS to the next evolutionary stage, to HOMO ingenious / S. G. Vari // The Ukrainian biochemical journal. - 2020. - Vol. 92, № 2. - P5-6

MeSH-головна:
ЧЕЛОВЕКА РАЗВИТИЕ -- HUMAN DEVELOPMENT (физиология)
Анотація: The worldwide COVID-19 (novel coronavirus) pandemic has created an unpredicted and unexperienced chain reaction for our human species Homo sapiens due to “social distancing” and community lockdowns. The situation is far beyond our “business as usual” mode and has become our “everyday functioning”. The pandemic is putting extreme pressure on healthcare systems and is significantly changing the economy, due to the lockdown of the workforce, therefore reducing the supply (output of industry), consumer demand for supplies, as well as consumer earnings and buying power. Therefore, the resulting reduced gross domestic product (GDP) will change the lives of individuals and communities, both small and large, not only for the next couple of months but for years
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Шифр: УУ60/2020/92/3
Журнал

The Ukrainian biochemical journal [Текст]. - Виходит раз на два місяця
2020р. Т. 92 № 3

Зміст:
Chernyshenko, V. Presenting thematic ’Molecular and clinical studies of hemostasis’ issue / V. Chernyshenko, S. Komisarenko. - P.5
Vari, S. G. COVID-19 infection: disease mechanism, vascular dysfunction, immune responses, markers, multiorgan failure, treatments, and vaccination / S. G. Vari : 21
Medved, L. Structure and function of fibrinogen BβN-Domains / L. Medved, S. Yakovlev. - P.22-32
Lugovskoi, E. The fibrin Bβ125-135 site is involved in the lateral association of protofibrils / E. Lugovskoi [et al.]. - P.33-45
Інші автори: Pydiura N., Makogonenko Y., Urvant L., Gritsenko P., Kolesnicova I., Lugovska N., Komisarenko S.
Kapustianenko, L. G. Identification of the binding site for plasminogen kringle 5 in the α-chain of fibrin(ogen) D-fragment / L. G. Kapustianenko [et al.]. - P.46-57
Інші автори: Grinenko T. V., Rebriev A. V., Yusova O. I., Tykhomyrov A. A.
Lugovska, N. E. Novel monoclonal antibody to fibrin(ogen) αC-region for detection of the earliest forms of soluble fibrin / N. E. Lugovska [et al.]. - P.58-70
Інші автори: Kolesnikova I. M., Stohnii Ye. M., Chernyshenko V. O., Rebriev A. V., Kostiuchenko O. P., Gogolinska G. K., Dziubliuk N. A., Varbanets L. D., Platonova T. M., Komisarenko D. V.
Mykhaloiko, I. S. D-dimer as a potential predictor of thromboembolic and cardiovascular complications in patients with chronic kidney disease / I. S. Mykhaloiko [et al.]. - P.71-76
Інші автори: Dudar I. O., Mykhaloiko I. Ja., Mykhaloiko O. Ja.
Panibratiuk, O. A. Warfarin therapy in patients with coronary heart disease and atrial fibrillation: drug interactions and genetic sensitivity to warfarin / O. A. Panibratiuk, O. A. Yakovleva. - P.77-85
Chernyshenko, V. O. Men of the molecules / V. O. Chernyshenko. - P.86-90
Григор’єва, М. В. 20 років тому завершилися "перегони" секвенування геному людини / М. В. Григор’єва ; М. В. Григор’єва, С. В. Комісаренко. - P.91-92
Danylova, T. V. Nobel prize winner erwin schrodinger: the physicist, philosopher, and godfather of molecular biology and genetics / T. V. Danylova, S. V. Komisarenko. - P.93-100
До 70-річчя від дня народження члена-кореспондента НАН України, професора Ростислава Стефановича Стойки. - P.101-102
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Vari, S. G.
COVID-19 infection: disease mechanism, vascular dysfunction, immune responses, markers, multiorgan failure, treatments, and vaccination / S. G. Vari // The Ukrainian biochemical journal. - 2020. - Vol. 92, № 3 : 21

MeSH-головна:
КОРОНАВИРУСНЫЕ ИНФЕКЦИИ -- CORONAVIRUS INFECTIONS (вирусология, генетика, диагностика, диетотерапия, иммунология, классификация, кровь, лекарственная терапия, метаболизм, микробиология, осложнения, патофизиология, передача, профилактика и контроль, смертность, терапия)
Анотація: The new SARS-CoV-2 virus is a great danger for the worldwide population since there is no known pre-immunity, no specific treatment, and no vaccine. Still, the testing and tracing are the best tools to isolate the infected and prevent the spread of COVID-19. The major goals are to save lives, reduce the mortality rate, increase the survival rate of those are in severe or critical conditions, reduce the hospital stay and accelerate the recovery. This review summarizes the findings on the novel coronavirus that causes COVID-19 and outlines information about symptoms, testing, disease mechanism, vascular dysfunction, immune responses, treatments, and vaccination. At this time no vaccine is available to prevent COVID-19. A literature review reveals that more research is necessary to investigate the interactions between respiratory viruses, human coronaviruses, and the new SARS-CoV-2 virus in the infected population to guide the design of COVID-19 specific therapeutics and vaccines. Almost every government on earth has realized that daily life cannot return to normal until citizens have built up antibodies to safeguard them from the virus. Scientists and manufacturers worldwide are accelerating COVID-19 vaccine research, and pharmaceutical companies are already investing in the large-scale production of vaccines. A synopsis of the most recent sources presented in this review was the starting point for several COVID-19 research projects in the Regional Cooperation for Health, Science and Technology (RECOOP HST) Association managed by Cedars – Sinai Medical Center to gain a better understanding of the COVID-19 disease
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Шифр: УУ60/2021/93/2
Журнал

The Ukrainian biochemical journal [Текст]. - Виходит раз на два місяця
2021р. Т. 93 № 2

Зміст:
Vari, S. G. Inflammation is the common mechanism of diseases (CMD) in COVID-19 disease during pregnancy and in gestational diabetes mellitus / S. G. Vari. - P.5
Kobylinska, L. In silico identification and biochemical validation of plausible molecular targets of 4-thiazolidinone derivative les-3833 as a potential anticancer agent / L. Kobylinska [et al.]. - P.7-23
Інші автори: Khylyuk D., Subtelna I., Kitsera M., Lesyk R.
Shevchuk, O. O. Locally delivered lovastatin-containing chitosan nanoparticles promote bone regeneration in rats / O. O. Shevchuk, Ya. V. Panasiuk, M. M. Korda. - P.24-38
Finiuk, N. S. Effect of a novel thiazole derivative and its complex with a polymeric carrier on stability of DNA in human breast cancer cells / N. S. Finiuk [et al.]. - P.39-52
Інші автори: Klyuchivska O. Yu., Ivasechko I. I., Mitina N. E., Ostapiuk Yu. V., Obushak M. D., Zaichenko O. S., Babsky A. M., Stoika R. S.
Poshyvak, O. B. Oxidative stress suppression contributes to antiseizure action of axitinib and rapamycin in pentylenetetrazol-induced kindling / O. B. Poshyvak, O. R. Pinyazhko, L. S. Godlevsky. - P.53-60
Korolova, D. S. Thromboelastographic study of fibrin clot and molecular basis of maximum clot firmness / D. S. Korolova [et al.]. - P.62-70
Інші автори: Stohnii Y. M., Gryshchuk V. I., Zhuk S. I., Us I. V., Chernyshenko T. M., Kostiuchenko O. P., Klymenko K. P., Platonov O. M., Ivashchenko O. I., Chernyshenko V. O.
Pavlyshyn, H. A. The association between vitamin D status and cardiometabolic disorders in overweight and obese adolescents / H. A. Pavlyshyn, A.-M. A. Shulha. - P.72-81
Pavlyshyn, H. A. Investigating the connections between night eating syndrome and metabolic syndrome in children / H. A. Pavlyshyn, K. V. Kozak, K. T. Hlushko. - P.83-94
Hlushko, K. T. Clinical and immunological peculiarities of parasitic infections in children with digestive system disorders in Western Ukraine / K. T. Hlushko, H. A. Pavlyshyn, K. V. Kozak. - P.96-105
Kucher, S. V. Inclusion of enterosorbents in anti-inflammatory therapy improve treatment effectiveness in COPD patients during exacerbations / S. V. Kucher, O. V. Lototska. - P.107-114
Danylova, T. V. Double Nobel prize winner: Frederick Sanger - the father of genomics / T. V. Danylova, S. V. Komisarenko. - P.116-122
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Vari, S. G.
Inflammation is the common mechanism of diseases (CMD) in COVID-19 disease during pregnancy and in gestational diabetes mellitus / S. G. Vari // The Ukrainian biochemical journal. - 2021. - Vol. 93, № 2. - P5

MeSH-головна:
БЕРЕМЕННОСТИ ОСЛОЖНЕНИЯ -- PREGNANCY COMPLICATIONS (патофизиология)
ДИАБЕТ ГЕСТАЦИОННЫЙ -- DIABETES, GESTATIONAL (патофизиология)
КОРОНАВИРУСНЫЕ ИНФЕКЦИИ -- CORONAVIRUS INFECTIONS (патофизиология)
КОМОРБИДНОСТЬ -- COMORBIDITY
Анотація: The Regional Cooperation for Health, Science and Technology (RECOOP HST) Consortium, led by Cedars-Sinai Medical Center was formed in 2006, was transformed into an Association in 2012 and includes 17 universities and academic organizations from eight countries: seven in Central and Eastern Europe (Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Ukraine) and the United States. RECOOP builds multinational, multidisciplinary collaborations, and assists as well as coordinates the research activities of the sixteen research groups that are the Cedars-Sinai Medical Center – RECOOP Research Centers (CRRCs). https://www.cedars-sinai.org/research/administration/recoop.html.
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(Асоціація ЕБНІТ)