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1.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Buchynska L. G., Movchan O. M., Iurchenko N. P.
Заглавие : Expression of chemokine receptor CXCR4 in tumor cells and content of CXCL12+ -fibroblasts in endometrioid carcinoma of endometrium
Место публикации : Experimental Oncology. - К., 2021. - Том 43, N 2. - С. 135-141 (Шифр ЕУ12/2021/43/2)
MeSH-главная: КАРЦИНОМА ЭНДОМЕТРИОИДНАЯ -- CARCINOMA, ENDOMETRIOID
Аннотация: The expression of the CXCL12 chemokine and its receptor CXCR4 in the stromal component of the tumor plays an important role in tumor cell migration, proliferation, inhibition of apoptosis and determination of invasive and metastatic potential of malignant neoplasms of various genesis. The significance of CXCL12 and CXCR4 expression in endometrial tumor cells for cancer progression is not fully understood. Aim: To evaluate the content of CXCL12+-fibroblasts and expression of CXCL12 and CXCR4 in endometrial cancer cells, depending on the tumor stage. Materials and Methods: Surgical material of 45 patients with endometrioid carcinoma of the endometrium (ECE) of the stages I–II and III was studied using morphological and immunohistochemical methods. Results: In ECE of stage I–II CXCR4 expression was lower (43.3 ± 4.2%) while CXCL12 expression was higher (33.6 ± 2.4%) compared with the corresponding indices​​ in ECE of stage III (63.6 ± 3.5%, 24.5 ± 1.9%, respectively, p 0.05). In ECE of stage III, high expression of CXCR4 ( Me) and low CXCL12 ( Me) was observed in 80% of samples; these tumors invaded more than 1/2 of the myometrium. There was a positive correlation between the depth of tumor invasion in the myometrium and the presence of metastases and CXCR4 expression in tumor cells (R Me) (14.9 ± 1.3%) was detected. Conclusion: The obtained data reflect the communication of the immunosuppressive factor of the tumor microenvironment, i.e. CXCL12+-fibroblasts and CXCR4 expressing tumor cells. We suggest that the aggressiveness of ECE is determined by the combined effect of these two factors
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2.

Заглавие журнала :Экспериментальная онкология -2021г. т.43,N 2
Интересные статьи :
Vitruk Yu. V. Evaluation of response to tyrosine kinase inhibitors in renal cell carcinoma patients based on expression of miR-99b, -144, -210, -222, -302a and -377 in tumor tissue/ Yu. V. Vitruk [et al.] (стр.98-103)
Pyaskovskaya O. N. Role of tumor/endothelial cell interactions in tumor growth and metastasis/ O. N. Pyaskovskaya [et al.] (стр.104-110)
Akalovich S. 5-FU resistens colorectal cancer cells possess improved invasiveness and βIII-tubulin expression/ S. Akalovich [et al.] (стр.111-117)
Bychkov V. A. In vitro modeling of tumor interclonal interactions using breast cancer cell lines/ V. A. Bychkov [et al.] (стр.118-124)
Ayyildiz A. Co-administration of apigenin with doxorubicin enhanges anti-migration and antiproliferative effects via PI3K/PTEN/AKT pathway in prostate cancer cells/ A. Ayyildiz [et al.] (стр.125-134)
Buchynska L. G. Expression of chemokine receptor CXCR4 in tumor cells and content of CXCL12+ -fibroblasts in endometrioid carcinoma of endometrium/ L. G. Buchynska, O. M. Movchan, N. P. Iurchenko (стр.135-141)
Yakovlev P. G. Expression of TLR4 and major inflammatory cytokines in patients with bladder cancer of different grade and stage/ P. G. Yakovlev [et al.] (стр.142-148)
Zoubi M. S. RAD51-UTR haplotype genetic polymorphisms and susceptibility to breast cancer in women from Jordanian population/ M. S. Zoubi [et al.] (стр.149-154)
Kornatska A. G. A variant of TP53 gene (RS 1625895, 13494GA) is associated with neoplasm localization in patients with uterine leiomyoma/ A. G. Kornatska [et al.] (стр.155-158)
Mohamed Yusoff A. A. Significance of BRAFv600E mutation in intra-axial brain tumor in Malaysian patients: case series and literature review/ A. A. Mohamed Yusoff [et al.] (стр.159-167)
Ben Kridis W. Therapeutic results of laryngeal preservation: a retrospective study/ W. Ben Kridis [et al.] (стр.168-172)
Pilinska M. A. Study of modifyng effects of astaxanthin on cytogenetic manifestations of bystander response in human peripheral blood lymphocytes in vitro/ M. A. Pilinska [et al.] (стр.173-176)
De Giorgi V. Scrotal cutaneous metastasis from rectal squamous cell carcinoma: a rare evolution into a rare tumor/ V. De Giorgi [et al.] (стр.177-179)
Liubota R. Systemic chemotherapeutic treatment of patients with breast cancer brain metastases/ R. Liubota [et al.] (стр.180-184)
Pasichnyk S. M. Predicting changes in glomerular filtration rate in patients with kidney cancer using a mathematical model/ S. M. Pasichnyk [et al.] (стр.185-188)
Gluzman D. F. Long-term exposure to low doses of ionizing radiation and COVID-19 pandemic: oncohematological aspects/ D. F. Gluzman [et al.] (стр.189-192)
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3.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Buchynska L. G., Naleskina L. A., Nesina I. P.
Заглавие : Morphological characteristics and expression of adhesion markers in cells of low differentiated endometrial carcinoma
Место публикации : Experimental Oncology. - К., 2019. - Том 41, N 4. - С. 335-341 (Шифр ЕУ12/2019/41/4)
Аннотация: The aim of the study was to evaluate the morphological features of endometrioid carcinoma of the endometrium (ECE) of low differentiation grade with different invasive potential and to characterize their molecular phenotype by the expression of a number of adhesion markers. Materials and Methods: We have studied the samples of operation material of 37 patients with ECE of low differentiation grade with deep invasion ( ½ myometrium), n = 26, and with invasion ½ myometrium, n
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4.

Заглавие журнала :Экспериментальная онкология -2019г. т.41,N 2
Интересные статьи :
Verma S. Evaluating the role of dithiolane rich fraction of Ferula asafoetida (apiaceae) for its antiproliferative and apoptotic properties: in vitro studies/ S. Verma [та ін.] (стр.90-94)
Syvyk A. E. Inducible dominant negative ErbB2 rat spermatogonial line for generation of transgenic rat model and dissecting ERBB2 tyrosine kinase mediated pathways/ A. E. Syvyk, T. L. Syvyk (стр.95-105)
Prylutska S. V. Antitumor effects and hematotoxicity of C60-Cis-Pt nanocomplex in mice with Lewis lung carcinoma/ S. V. Prylutska [та ін.] (стр.106-111)
Petrellis M. C. Proinflammatory effects of photoactivated methylene blue on rat model of Walker 256 carcinosarcoma/ M. C. Petrellis [та ін.] (стр.112-122)
Kolesnik D. L. Metformin enhances antitumor action of sodium dichloroacetate against glioma C6/ D. L. Kolesnik [та ін.] (стр.123-129)
Herrera-Covarrubias D. Prepuberal stress and obesity: effects on serum corticosterone, prolactin, testosterone and precancerous prostate lesions in adult rats/ D. Herrera-Covarrubias [та ін.] (стр.130-137)
Buchynska L. G. Assessment of HER-2/neu, с-MYC and CCNE1 gene copy number variations and protein expression in endometrial carcinomas/ L. G. Buchynska, O. V. Brieiev, N. P. Iurchenko (стр.138-143)
Kravets O. V. Clinical and pathological prognostic factors in patients with stage III–IVA-B oral squamous cell carcinoma/ O. V. Kravets [та ін.] (стр.144-147)
Burlaka A. P. Tumor-associated redox state in metastatic colorectal cancer/ A. P. Burlaka [та ін.] (стр.148-152)
Tajaldeen A. Investigation of dosimetric impact of organ motion in static and dynamic conditions for three stereotactic ablative body radiotherapy techniques: 3D conformal radiotherapy, intensity modulated radiation therapy, and volumetric modulated arc therapy by usi/ A. Tajaldeen, S. Alghamdi (стр.153-159)
Yakovlev P.G. Bladder sparing surgery in high-grade bladder cancer/ P. G. Yakovlev, D. A. Klyushin, R. I. Vereshchako (стр.160-165)
Cešeiko R. The impact of maximal strength training on quality of life among women with breast cancer undergoing treatment/ R. Cešeiko [та ін.] (стр.166-172)
Ben Kridis W. Prognostic factors in metastatic gastric carcinoma/ Kridis W. Ben [та ін.] (стр.173-175)
Dumanskiy Y. V. The Kі-67 marker for assessing the effectiveness of systemic or regional neoadjuvant polychemotherapy in patients with locally advanced breast cancer/ Y. V. Dumanskiy, O. V. Bondar, E. A. Stoliarchuk (стр.176-178)
Starchenko I. I. The observation of congenital retroperitoneal large size neuroblastoma / I. I. Starchenko [та ін.] (стр.179-181)
Ben Kridis W. Buschke — Lowenstein anal tumor: an ambiguous entity/ Kridis W. Ben [та ін.] (стр.182-184)
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5.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Buchynska L. G., Brieiev O. V., Iurchenko N. P.
Заглавие : Assessment of HER-2/neu, с-MYC and CCNE1 gene copy number variations and protein expression in endometrial carcinomas
Место публикации : Экспериментальная онкология. - 2019. - Т. 41, № 2. - С. 138-143 (Шифр ЕУ12/2019/41/2)
Примечания : Bibliogr. at the end of the art.
Аннотация: To analyze copy number variations of HER-2/neu, c-MYC and CCNE1 oncogenes and their protein expression in endometrioid endometrial carcinomas in relation to the degree of tumor progression and presence of a family history of cancer in cancer patients. Materials and Methods: The study was conducted on endometrial cancer (EC) samples from 68 patients with I–II FIGO stages of disease. Copy number analysis of HER-2/neu, c-MYC and CCNE1 genes was performed by quantitative PCR. Protein expression was analyzed using immunohistochemistry. Results: Assessment of copy number variations of HER-2/neu, c-MYC and CCNE1 genes revealed their amplification in the tumors of 18.8, 25.0 and 14.3% of EC patients, respectively. High expression of corresponding proteins was detected in 14.6, 23.5 and 65.6% of patients, respectively. It was established that HER-2/neu gene amplification is more common in the group of tumors of low differentiation grade than in moderate grade EC (35.7 and 5.5% of cases, respectively, p 0.05). Also, high expression of c-Myc protein was more frequently observed in low differentiated tumors compared to the moderately differentiated EC (36.6 and 13.2% of cases, respectively, p 0.05). Expression of HER-2/neu and cyclin E proteins was found to be dependent on the depth of tumor invasion into the myometrium. High expression of HER-2/neu protein was observed in 25.0 and 4.1% of EC patients with tumor invasion ½ and ½ of the myometrium, respectively, and cyclin E — in 86.7 and 46.6% of cases, respectively, p 0.05. It was shown that among patients with a family history of cancer, a larger proportion of cases with high expression of c-Myc protein was observed compared to the group of patients with sporadic tumors (43.8 and 17.3%, respectively; p 0.05). Conclusions: Amplification of HER-2/neu gene, along with high expression of c-Myc, HER-2/neu and cyclin E proteins, are associated with such indices of tumor progression as a low differentiation grade and deep myometrial invasion, suggesting the potential possibility of including these markers in the panel for determining the molecular EC subtype associated with an aggressive course of the disease. In a certain category of EC patients, there is a relationship between a family history of cancer and high expression of c-Myc protein
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6.

Заглавие журнала :Экспериментальная онкология -2019г. т.41,N 4
Интересные статьи :
Karaman O. M. Macrophages - a perspective target for antineoplastic immunotherapy/ O. M. Karaman, A. V. Ivanchenko, V. F. Chekhun (стр.282-290)
Orel V. E. Nоn-linear dynamics theory and malignant melanoma/ V. E. Orel [et al.] (стр.291-299)
Lisyany N. I. Cytomegaloviruses and malignant brain tumors/ N. I. Lisyany [et al.] (стр.300-303)
Woksepp H. Proteomics of transforming growth factor β1 (TGF β1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2α in TGF β1-dependent p53 phosphorylation at Ser392/ H. Woksepp [et al.] (стр.304-311)
Dehghan Nayeri M. J. Apoptosis-inducing effect of spiroaminopyrimidine analogue in NB 4 leukemia cells via down-regulation of BIRC5 expression/ Nayeri M. J. Dehghan [et al.] (стр.312-317)
Albuquerque A. P. B. Fut3 expression in human breast cancer cells under hypoxia and serum deprivation/ A. P. B. Albuquerque [et al.] (стр.318-322)
Skuja E. Deletions in metastatic colorectal cancer with chromothripsis/ E. Skuja [et al.] (стр.323-327)
Burlaka A. P. Molecular mechanisms of oxidation damage and liver cell dysfunction in patients with metastatic colorectal cancer/ A. P. Burlaka [et al.] (стр.328-334)
Buchynska L. G. Morphological characteristics and expression of adhesion markers in cells of low differentiated endometrial carcinoma/ L. G. Buchynska, L. A. Naleskina, I. P. Nesina (стр.335-341)
Zelinskaya A. Immunocytochemical characteristics of thyrocytes in radioiodine refractory metastases of papillary thyroid cancer/ A. Zelinskaya (стр.342-345)
Moazeni-Roodi A. Association bewtween XPO5 rs 1 1077 polymorphism and cancer susceptibility: a meta-analysis of 7284 cases and 85 1 1 controls/ A. Moazeni-Roodi, M. Taheri, M. Hashemi (стр.346-352)
Skrypnyk I. How to improve quality of life in patients with acute leukemia and comorbid ischemic heart disease treated with anthracycline-based induction chemotherapy/ I. Skrypnyk [et al.] (стр.353-356)
Gavars D. Association of elevated vitamin B12 with oncohematological diseases in a cohort of 79, 524 patients from Lanvia/ D. Gavars [et al.] (стр.357-362)
Prylutskyi M. P. Detection of polyamines using immunobiosensor based on zinc oxide nanoparticles/ M. P. Prylutskyi, M. F. Starodub (стр.363-365)
Shkatula P. M. International scientific conference "Tumor and Host: novel aspects of old problem"/ P. M. Shkatula (стр.366-367)
To the 120th birthday anniversary of academician R. E. Kavetsky (стр.368-369)
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7.

Заглавие журнала :Экспериментальная онкология -2018г. т.40,N 3
Интересные статьи :
Akbarzadeh A. Role of dendrimers in advanced drug delivery and biomedical applications: a review/ A. Akbarzadeh [та ін.] (стр.178-183)
Zadvornyi T. V. Effects of exogenous lactoferrin on phenotypic profile and invasiveness of human prostate cancer cells (DU145 and LNCaP) in vitro/ T. V. Zadvornyi [та ін.] (стр.184-189)
Harper P. The impact of morphine treatment on bladder cancer cell proliferation and apoptosis: in vitro studies/ P. Harper [та ін.] (стр.190-193)
Apykhtina О. L. Cytotoxic and genotoxic effects of cadmium sulfide nanoparticles/ О. L. Apykhtina [та ін.] (стр.194-199)
Chekhun V. F. Antitumor and genotoxic effects of lactoferrin in Walker-256 tumor-bearing rats/ V. F. Chekhun [та ін.] (стр.200-204)
Prokhorova I. V. Influence of metformin, sodium dichloroacetate and their combination on the hematological and biochemical blood parameters of rats with gliomas C6/ I. V. Prokhorova [та ін.] (стр.205-210)
Abramenko I. V. . Analysis of the 3′UTR region of the NOTCH1 gene in chronic lymphocytic leukemia patients/ I. V. Abramenko [та ін.] (стр.211-217)
Nesina I. P. Markers of the epithelial-mesenchymal transition in cells of endometrial carcinoma/ I. P. Nesina, N. P. Iurchenko, L. G. Buchynska (стр.218-222)
Vernygorodskyi S. Comparative histochemical evaluation of mucins expression in fetal esophagus and adenocarcinomas of the gastroesophageal junction/ S. Vernygorodskyi, T. Rekun, P. Zhuchenko (стр.223-227)
Gerashchenko T. S. Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles/ T. S. Gerashchenko [та ін.] (стр.228-234)
Agishev T. T. Determination of oxygen perfusion in the area of radiation-induced fibrosis of the skin in patients with breast cancer and its role in pathogenesis of late radiation injury/ T. T. Agishev [та ін.] (стр.235-238)
Dumansky Yu. V. Paraneoplastic syndrome in lung cancer/ Yu. V. Dumansky [та ін.] (стр.239-242)
Grybach S. M. Analysis of the survival of patients with breast cancer depending on age, molecular subtype of tumor and metabolic syndrome/ S. M. Grybach, L. Z. Polishchuk, V. F. Chekhun (стр.243-248)
Chrysanthakopoulos N. A. ABO blood group and the risk of lung cancer in Greek adults: a case — control study/ N. A. Chrysanthakopoulos, N. S. Dareioti (стр.249-250)
Tkachenko R. A case report of late local relapse of adrenocortical carcinoma 18 years after adrenalectomy/ R. Tkachenko, A. Golovko, O. Kuryk (стр.251-253)
Svitlana Pavlivna Sidorenko (1953–2018) (стр.254-255)
Yurii Yosypovych Kudryavets (1946–2018) (стр.256-257)
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8.

Заглавие журнала :Экспериментальная онкология -2018г. т.40,N 1
Интересные статьи :
Kian R. Role of components of microRNA machinery in carcinogenesis/ R. Kian, S. Moradi, S. Ghorbian (стр.2-9)
Patel K. R. Clinical implications of p53 alterations in oral cancer progression: a review from India/ K. R. Patel [та ін.] (стр.10-18)
Varela-Castillo O. Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach/ O. Varela-Castillo [та ін.] (стр.19-23)
Chaves K. C. B. Impact of endostatin gene therapy on myeloid-derived suppressor cells from a metastatic renal cell carcinoma/ K. C. B. Chaves [та ін.] (стр.24-32)
Sarnatskaya V. V. Highly activated carbon enterosorbent mediates the suppression of paraneoplastic syndrome associated with lewis lung carcinoma in mice/ V. V. Sarnatskaya [та ін.] (стр.33-41)
Boroday N. V. Morphological features of doxorubicin-resistant Walker 256 carcinosarcoma and response of mast cells/ N. V. Boroday, V. F. Chekhun (стр.42-47)
Kurtenkov O. Signatures of anti-Thomsen — friedenreich antigen antibody diversity in colon cancer patients/ O. Kurtenkov, M. Bubina, K. Klaamas (стр.48-58)
Paliychuk O. V. Molecular-genetic models for prognosis of development of tumors of reproductive system in women with family history of cancer/ O. V. Paliychuk [та ін.] (стр.59-67)
Buchynska L. G. Sensitivity to 4-hydroxyestradiol and dna repair efficiency in peripheral blood lymphocytes of endometrial cancer patients/ L. G. Buchynska, O. V. Brieieva (стр.68-72)
Lozynska L. Y. Variant of rare hermansky — pudlak syndrome associated with granulomatous colitis: diagnostics clinical course and treatment/ L. Y. Lozynska [та ін.] (стр.73-78)
Zubenko O. S. Effect of cytostatic agents on expression levels of human beta-defensins-1-4 in A431 and MCF-7 cell lines/ O. S. Zubenko [та ін.] (стр.79-81)
Imaniar R. Mediastinal yolk sac tumor infiltrating the heart/ R. Imaniar [та ін.] (стр.82-84)
Ben Kridis W. A long survival of a patient with brain metastasis of unknown site of the primary tumor/ Kridis W. Ben [та ін.] (стр.85-87)
Symposium and Summer School “Fundamental principles of cancer biotherapy” Kyiv Ukraine May 21-24 2018 (стр.88)
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9.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Buchynska L. G., Brieieva O. V.
Заглавие : Sensitivity to 4-hydroxyestradiol and dna repair efficiency in peripheral blood lymphocytes of endometrial cancer patients
Место публикации : Экспериментальная онкология. - 2018. - Т. 40, № 1. - С. 68-72 (Шифр ЕУ12/2018/40/1)
Примечания : Bibliogr. at the end of the art.
MeSH-главная: НОВООБРАЗОВАНИЯ ГОРМОНОЗАВИСИМЫЕ -- NEOPLASMS, HORMONE-DEPENDENT
КАРЦИНОМА ЭНДОМЕТРИОИДНАЯ -- CARCINOMA, ENDOMETRIOID
ЛИМФОЦИТЫ -- LYMPHOCYTES
ДНК ПОВРЕЖДЕНИЕ -- DNA DAMAGE
РИСКА СТЕПЕНИ ОЦЕНКА -- RISK ADJUSTMENT
СТАТИСТИЧЕСКАЯ ОБРАБОТКА ДАННЫХ -- DATA INTERPRETATION, STATISTICAL
Аннотация: The development of hormone-dependent cancers, including endometrial carcinomas, in great part may be mediated by the genotoxic effects of estrogen metabolites, among which 4-hydroxyestradiol (4OHE2) is characterized by the most prominent DNA-damaging properties. It is assumed that the individual sensitivity to the 4OHE2 may determine the predisposition to endometrial cancer (EС). Aim: To analyze the sensitivity of peripheral blood lymphocytes (PBLs) of EC patients to the 4OHE2 and to evaluate the repair efficiency of 4OHE2-induced DNA damage. Materials and Methods: The study was performed on the PBLs of 53 EC patients and 20 healthy women. The level of DNA damage was measured using the comet assay and was expressed as % tail DNA. The DNA repair efficiency (%) was evaluated by determining the ratio between the amount of repaired DNA damage and the level of 4OHE2-induced damage that appeared after incubation of PBLs with 4OHE2. Results: In PBLs of EC patients, a higher level of 4OHE2-induced DNA damage (32.0 ± 2.2% tail DNA) and lower DNA repair efficiency (34.0 ± 4.5%) was observed compared to PBLs of healthy women (22.3 ± 2.3% tail DNA and 48.8 ± 4.5%, respectively). PBLs of EC patients with deep tumor invasion of myometrium were characterized by more prominent decrease of DNA repair than those with less invasive tumor ( ½ of myometrium) (20.9 ± 7.8 and 43.7 ± 6.7%, respectively). Furthermore, lower DNA repair efficiency was detected in the PBLs of EC patients with a family history of cancer compared to this parameter in patients with sporadic tumors (20.9±7.8 and 47.1 ± 5.5%, respectively). Conclusion: The PBLs of EC patients are characterized by increased sensitivity to the genotoxic effect of 4OHE2 and reduced repair efficiency regarding 4OHE2-induced DNA damage. A lower level of DNA repair is observed in EC patients with deep tumor myometrial invasion and a family history of cancer
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10.

Заглавие журнала :Экспериментальная онкология -2018г. т.40,N 4
Интересные статьи :
Chekhun V. F. Oncology in the mainstream of the National academy of sciences of Ukraine: to the 100th anniversary of the academy/ ed. V. F Chekhun (стр.258-260)
Tari K. The role of the genetic abnormalities, epigenetic and microRNA in the prognosis of chronic lymphocytic leukemia/ K. Tari [et al.] (стр.261-267)
Chekhun V. F. Influence of ferromagnetic nanocomposite (ferroplat) on human breast cancer cells of different malignancy degrees: pro/antioxidant balance and energy metabolism/ V. F. Chekhun [et al.] (стр.268-274)
Symchych T. V. The effects of early postoperative immunization with xenogeneic embryo proteins on Lewis lung carcinoma model/ T. V. Symchych [et al.] (стр.275-281)
Yakymenko I. Oxidative and mutagenic effects of low intensity GSM 18OO MHz microwave radiation/ I. Yakymenko [et al.] (стр.282-287)
Smal M. P. Ber gene polymorphisms associated with key molecular events in bladder cancer/ M. P. Smal [et al.] (стр.288-298)
Abooshahab R. Serum level dipeptidyl peptidase-4 as a potential biomarker for medullary thyroid cancer/ R. Abooshahab [et al.] (стр.299-302)
Buchynska L. G. Overexpression of the mitochondrial ribosomal protein S 18-2 in the invasive breast carcinomas/ L. G. Buchynska [et al.] (стр.303-308)
Arabpour F. FoxP3 gene polymorphism is associated with breast cancer in iranian patients/ F. Arabpour [et al.] (стр.309-314)
Gerashchenko G. V. Expression pattern of genes associated with tumor microenvironment in prostate cancer/ G. V. Gerashchenko [et al.] (стр.315-322)
Tas F. Clinical significance of serum caveolin-1 levels in gastric cancer patients/ F. Tas [et al.] (стр.323-327)
Shvachko L. P. Vitamin E activates expression of C/EBP alpha transcription factor and G-CSF receptor in leukemic K562 cells/ L. P. Shvachko [et al.] (стр.328-331)
Kuzyk P. V. Rare case of nodular lymphoid hyperplasia of left lung in the patient with previous pulmonary tuberculosis/ P. V. Kuzyk, M. A. Savchyna, S. G. Gychka (стр.332-335)
Zakhartseva L. M. Metastatic cardiac tumors: literature review and own observation of testicular tumor metastasis in the right ventricle of the heart/ L. M. Zakhartseva [et al.] (стр.336-342)
Langabeer S. E. The JAK2 V617F mutation in lung cancer: caveat emptor/ S. E. Langabeer (стр.343-344)
Professor Volodymyr Oleksiiovych Shlyakhovenko (on the 80th birth anniversary) (стр.345)
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