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1.

Заглавие журнала :Экспериментальная онкология -2020г. т.42,N 4
Интересные статьи :
Commitment to ideals of science. To the 90th birthday anniversary of academician Vadym Pinchuk (стр.250-251)
Naleskina L. A. Modern views on the role of main components of stroma and tumor microinvironment in invasion, migration and metastasis/ L. A. Naleskina, L. M. Kunska, V. F. Chekhun (стр.252-262)
Gaptulbarova K. A. NF-kB as a potential prognostic marker and a candidate for targeted therapy of cancer/ K. A. Gaptulbarova [та ін.] (стр.263-269)
Tykhomyrov A. A. Plasminogen/plasmin affects expression of glycolysis regulator TIGAR and induces autophagy in lung adenocarcinoma A549 cells/ A. A. Tykhomyrov [та ін.] (стр.270-276)
Kumar A. Microarray based gene expression profiling of advanced gall bladder cancer/ A. Kumar [та ін.] (стр.277-284)
Auziņa D. Dickkopf-related protein 1 expression in bone marrow of multiple myeloma patients: correlation with bone disease and plasma cell malignancy type/ D. Auziņa [та ін.] (стр.285-288)
Buchynska L. G. Expression of microRNA in tumor cells of endmetrioid carcinoma of endometrium/ L. G. Buchynska [та ін.] (стр.289-294)
Kovalevska L. Expression pattern of MRPS18 family genes in malignantly transformed b-cells/ L. Kovalevska, E. Kashuba (стр.295-299)
Buchynska L. G. Molecular phenotype of high-grade endometrioid carcinoma of the endometrium/ L. G. Buchynska [та ін.] (стр.300-305)
Shamrai D. Granulosa and theca cell tumor in rat’s ovary after modified Biskind operation/ D. Shamrai, E. Koshik, N. Melnyk (стр.306-309)
Bolgova L. S. Histogenesis of central lung cancer: cytological investigation/ L. S. Bolgova [та ін.] (стр.310-313)
Shcherbynina M. Histological criteria for “intraepithelial squamous cell carcinoma” of the esophagus: continued dialogue between Ukrainian and Japanese pathologists/ M. Shcherbynina, M. Itabashi, N. Soloviova (стр.314-317)
Yevstakhevych Yu. L. Autoimmune cytopenia in chronic lymphocytic leukemia: diagnosis and treatment/ Yu. L. Yevstakhevych [та ін.] (стр.318-323)
Korovin S. Burden of malignant melanoma in Ukraine in 2002–2013: incidence, mortality and survival/ S. Korovin [та ін.] (стр.324-329)
Burlaka A. P. Cytochrome P450 content in primary tumors and liver metastases of patients with metastatic colorectal cancer/ A. P. Burlaka [та ін.] (стр.330-332)
Kitsera N. Woman with Turner syndrome and her child with acute leukemia (a case report)/ N. Kitsera, O. Dorosh, H. Makukh (стр.333-336)
Buchatskyi L. P. Hypoxia induces melanotic pseudotumors in the larvae of mosquitoes of Culicidae family/ L. P. Buchatskyi (стр.337)
Mykola Oleksandrovych Druzhyna (1940–2020) (стр.338)
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2.

Заглавие журнала :Экспериментальная онкология -2020г. т.42,N 3
Интересные статьи :
Chekhun V. F. Association of circulating miR-21, -205, and -182 with response of luminal breast cancers to neoadjuvant FAC and AC treatment/ V. F. Chekhun [та ін.] (стр.162-166)
Kirkilevsky S. I. Prognostic significance of microRNA-200b and ERCC1 expression in tumor cells of patients with esophageal cancer/ S. I. Kirkilevsky [та ін.] (стр.167-171)
Abramenko I. V. Analysis of immunoglobulin heavy variable chain rearrangement in chronic lymphocytic leukemia patients among Chornobyl clean-up workers/ I. V. Abramenko [та ін.] (стр.172-177)
Ghosh S. K. Antiproliferative and apoptotic effect of ethanolic extract of Calocybe indica on PANC-1 and MIAPaCa2 cell lines of pancreatic cancer/ S. K. Ghosh, T. Sanyal (стр.178-182)
Sanaei M. Effect of valproic acid and zebularine on SOCS-1 and SOCS-3 gene expression in colon carcinoma SW48 cell line/ M. Sanaei, F. Kavoosi, H. Behjoo (стр.183-187)
Mehri S. Osteopontin siRNA does not confer resistance to toxic effects of parthenolide in Jurkat cells/ S. Mehri [та ін.] (стр.188-191)
Pyaskovskaya O. N. Tumor microenvironment changes tumor cell sensitivity to action of energy metabolism modifiers/ O. N. Pyaskovskaya [та ін.] (стр.192-196)
Symchych T. V. Functions of tumor-associated macrophages and macrophages residing in remote anatomical niches in Ehrlich carcinoma bearing mice/ T. V. Symchych [та ін.] (стр.197-203)
Todor I. N. Biomagnetism of tumor in rats with Guerin’s carcinoma after injection of ferromagnetic nanocomposite (Ferroplat): contactless measurement/ I. N. Todor [та ін.] (стр.204-207)
Çavuş B. Assessment of prognostic and diagnostic value of some biomarkers in hepatocellular carcinoma/ B. Çavuş [та ін.] (стр.208-214)
Babkina T. M. Detection of breast cancer presenting as a mass in women with dense breasts — digital breast tomosynthesis versus full-field digital mammography/ T. M. Babkina [та ін.] (стр.215-219)
Dumanskiy Y. V. Comparative evaluation of purine dysmetabolism in gastric and pulmonary adenocarcinomas/ Y. V. Dumanskiy [та ін.] (стр.220-223)
Stakhovskyi O. E. Quality of life in patients after radical cystectomy with modified ureterocutaneostomy and Bricker urinary diversion/ O. E. Stakhovskyi [та ін.] (стр.224-227)
Kravets O. V. Comparative analysis of the efficacy of definitive chemoradiation therapy and surgery followed by adjuvant radiation therapy in advanced-stage oral tongue cancer/ O. V. Kravets [та ін.] (стр.228-232)
Baranovska V. V. Histological differential diagnostics of renal oncocytoma/ V. V. Baranovska, A. M. Romanenko, L. M. Zakhartseva (стр.233-237)
Trociukas I. Progressive multifocal encephalopathy in a patient with non-Hodgkin follicular lymphoma/ I. Trociukas [та ін.] (стр.238-241)
Golovko A. Thyroid metastasis of vaginal leiomyosarcoma: a case report and review of the literature/ A. Golovko [та ін.] (стр.242-244)
Filenko B. M. Clinicomorphological observation of refractory hepatoblastoma: a case report/ B. M. Filenko [та ін.] (стр.245-247)
Zinovkin D. A. Water clear cell adenoma of parathyroid gland: a rare lesion/ D. A. Zinovkin, M. Yu. Zhandarov, M. Z .I. Pranjol (стр.248)
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3.

Заглавие журнала :Экспериментальная онкология -2019г. т.41,N 4
Интересные статьи :
Karaman O. M. Macrophages - a perspective target for antineoplastic immunotherapy/ O. M. Karaman, A. V. Ivanchenko, V. F. Chekhun (стр.282-290)
Orel V. E. Nоn-linear dynamics theory and malignant melanoma/ V. E. Orel [et al.] (стр.291-299)
Lisyany N. I. Cytomegaloviruses and malignant brain tumors/ N. I. Lisyany [et al.] (стр.300-303)
Woksepp H. Proteomics of transforming growth factor β1 (TGF β1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2α in TGF β1-dependent p53 phosphorylation at Ser392/ H. Woksepp [et al.] (стр.304-311)
Dehghan Nayeri M. J. Apoptosis-inducing effect of spiroaminopyrimidine analogue in NB 4 leukemia cells via down-regulation of BIRC5 expression/ Nayeri M. J. Dehghan [et al.] (стр.312-317)
Albuquerque A. P. B. Fut3 expression in human breast cancer cells under hypoxia and serum deprivation/ A. P. B. Albuquerque [et al.] (стр.318-322)
Skuja E. Deletions in metastatic colorectal cancer with chromothripsis/ E. Skuja [et al.] (стр.323-327)
Burlaka A. P. Molecular mechanisms of oxidation damage and liver cell dysfunction in patients with metastatic colorectal cancer/ A. P. Burlaka [et al.] (стр.328-334)
Buchynska L. G. Morphological characteristics and expression of adhesion markers in cells of low differentiated endometrial carcinoma/ L. G. Buchynska, L. A. Naleskina, I. P. Nesina (стр.335-341)
Zelinskaya A. Immunocytochemical characteristics of thyrocytes in radioiodine refractory metastases of papillary thyroid cancer/ A. Zelinskaya (стр.342-345)
Moazeni-Roodi A. Association bewtween XPO5 rs 1 1077 polymorphism and cancer susceptibility: a meta-analysis of 7284 cases and 85 1 1 controls/ A. Moazeni-Roodi, M. Taheri, M. Hashemi (стр.346-352)
Skrypnyk I. How to improve quality of life in patients with acute leukemia and comorbid ischemic heart disease treated with anthracycline-based induction chemotherapy/ I. Skrypnyk [et al.] (стр.353-356)
Gavars D. Association of elevated vitamin B12 with oncohematological diseases in a cohort of 79, 524 patients from Lanvia/ D. Gavars [et al.] (стр.357-362)
Prylutskyi M. P. Detection of polyamines using immunobiosensor based on zinc oxide nanoparticles/ M. P. Prylutskyi, M. F. Starodub (стр.363-365)
Shkatula P. M. International scientific conference "Tumor and Host: novel aspects of old problem"/ P. M. Shkatula (стр.366-367)
To the 120th birthday anniversary of academician R. E. Kavetsky (стр.368-369)
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4.

Заглавие журнала :Экспериментальная онкология -2017г. т.39,N 1
Интересные статьи :
Circulating tumor cells in breast cancer (стр.2-11)
Kashuba E. Do MRPS 18-2 and RB proteins cooperate to control cell stemness and differentiation, preventing cancer development?/ E. Kashuba, M. Mushtag (стр.12-16)
Effect of antitumor drugs in low concentrations on the biological, immunophenotypic and cytogenetic characteristics of human colon cancer cells in vitro (стр.17-24)
Artemisinin modulating effect on human breast cancer cell lines with different sensitivity to cytostatics (стр.25-29)
Parthenolide reduces gene transcription of prosurvival mediators in U937 cells (стр.30-35)
Anti-histone H1 IgGs prossess proliferative activity towards human T-leukemia CEM cells (стр.36-41)
Anticancer effect and immunologic response to xenogeneic embryonic proteins in mice bearing Ehrlich solid carcinoma (стр.42-48)
EPR spectroscopy studies of changes in erythrocyte membranes in patients with laryngeal cancer (стр.49-52)
Auzina D. Prognostic value of the bone turnover markers in multiple myeloma/ D. Auzina, R. Erts, S. Lejniece (стр.53-56)
Aberrant promoter hypermethylation of selected apoptotic genes in childhood acute lymphoblastic leukemia among North Indian population (стр.57-64)
Chekhun V.F. Significance of iodine symporter for prognosis of the disease course and efficacy of neoadjuvant chemotherapy in patients with breast cancer of luminal and basal subtypes/ V. F. Chekhun, A. V. Andriiv, N. Yu. Lukianova (стр.65-68)
Satinder K. Impact of single nucleotide polymorphism in chemical metabolizing genes and exposure to wood smoke on risk of cervical cancer in North-Indian women/ K. Satinder, R. C. Sobti, K. Pushpinder (стр.69-74)
The impact of coloregional treatment on survival of patients with primary metastatic breast cancer (стр.75-77)
Diagnostic challenges with intraoral myeloid sarcoma (стр.78-85)
Trichilemmal cystis in metastatic melanoma (стр.86-87)
Materials of international vactrain/ 3-rd Swedish-Ukrainian conference on cancer diseases, January 16-17, 2017, Stockholm, Sweden (стр.88-93)
Endoplasmic reticulum stress as a key factor of genome reprogramming in cancer cells (стр.88-89)
The adaptor protein Ruk/CIN85 paradoxically enhances EMT of triple negative mouse breast adenocarcinoma 4T1 cells (стр.89)
Biological characteristics of tumor cells at the different stages of EMT upon exposure to anticancer drugs and cytokines (стр.89-90)
Alternative direction of inhibition of malignant properties in tumor cells in vitro and in vivo by gene therapy with INF-beta gene in recombinant baculovirus vector (стр.90)
CD150/SLAMF1 as a new potential target for anti-tumor therapy (стр.90-91)
CD150/SLAMF1 antigen in molecular pathobiology of chronic lymphocytic leukemia (стр.91-92)
Borikun T. Changes in expression of miRNA-122, -200b, and -320a as prognostic biomarkers for breast cancer/ T. Borikun, N. Lukianova, V. Chekhun (стр.92)
The MRPS 18-2 protein as a putative marker of carcinogenesis (стр.92)
High expression levels of MRPS 18-2 and presence of the RB protein are required for the maintenance of stem cell phenotype (стр.92-93)
Mankovska O. Identification of novel molecular and genetic markers for early detection and prognosis of epithelial tumors/ O. Mankovska, V. Kashuba (стр.93)
Brieieva O. Genotoxic sensitivity to 4-hydroxyestradiol in peripheral blood lymphocytes of endometrial cancer patients/ O. Brieieva, I. Nesina, L. Buchynska (стр.93)
Kyiv, May 11-12, 2017 Workshop with international participation. New trends in cancer research and innovative tumor vaccines (стр.94)
International scientific conference "Normal and and cancer stem cells: discovery, diagnosis and therapy", October 5-6, 2017, Kyiv, Ukraine (стр.95)
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5.

Заглавие журнала :Внутрішня медицина -2009г.,N 5/6
Интересные статьи :
Рекомендації Європейського товариства кардіологів з діагностики та лікування легеневої гіпертензії (2009 р.)- (стр.5-15)
Рекомендації Європейського товариства кардіологів щодо ведення хворих, які підлягають некардіального ризику і кардіологічне лікування при несерцевій хірургії (стр.16-25)
Рекомендації Європейського товариства кардіологів щодо діагностики та лікування синкопальних станів (оновлені 2009 р.) (стр.26-42)
Kоhler H. P. Місце і роль антикоагулянтної терапії у профілактиці тромбозів у пацієнтів терапевтичного та хірургічного профілю/ H. P. Kоhler (стр.43-47)
Kоhler H. P. Фактор ХІІІ: його роль у розвитку гемофілії та тромбозів/ H. P. Kоhler (стр.48-50)
Діагностика виникнення ранніх серцево-сулинних подій у спортсменів (за матеріалами Європейського конгресу кардіологів, Барселона, 2009 р.) (стр.51-54)
Надання невідкладної медичної допомоги на догоспітальному етапі пацієнтам із ГКС у Франції та Америці (за матеріалам Європейського конгресу кардіологів, Барселона, 2009 р.) (стр.55-57)
Lejniece S. Гемолітичні анемії/ S. Lejniece (стр.58-61)
Lejniece S. Тромбоцитопения/ S. Lejniece (стр.62-68)
Dukat A. Ретинопатия Пуртшера как осложнение острого панкреатита/ A. Dukat (стр.69-74)
Нетяженко В. З. Сучасні аспекти застосування статинів при гострому коронарному синдромі/ В. З. Нетяженко, Б. М. Юрочко (стр.75-84)
Серцева недостатність: що нового? (Барселона, 2009) (стр.85-90)
MacFadyen R.J. Майбутнє бета-блокади/ R. J. MacFadyen (стр.91-98)
Bitterman H. Диагностика венозной тромбоэмболии: что нового?/ H. Bitterman (стр.99-109)
Косарчук В. В. Основні константи внутрішнього середовища та функції організму людини (ІІІ частина)/ В. В. Косарчук [и др.] (стр.110-135)
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6.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Trociukas I., Zirnis A. E., Beļajeva L., Rivkina A., Lejniece S.
Заглавие : Progressive multifocal encephalopathy in a patient with non-Hodgkin follicular lymphoma
Место публикации : Экспериментальная онкология. - 2020. - Т. 42, № 3. - С. 238-241 (Шифр ЕУ12/2020/42/3)
Примечания : Бібліогр.: в кінці ст.
MeSH-главная: ОПИСАНИЕ СЛУЧАЕВ -- CASE REPORTS
ЛЕЙКОЭНЦЕФАЛОПАТИИ -- LEUKOENCEPHALOPATHIES
БОЛЕЗНИ РЕДКИЕ -- RARE DISEASES
ЛИМФОМА ФОЛЛИКУЛЯРНАЯ -- LYMPHOMA, FOLLICULAR
КРОВЕТВОРНЫХ СТВОЛОВЫХ КЛЕТОК ТРАНСПЛАНТАЦИЯ -- HEMATOPOIETIC STEM CELL TRANSPLANTATION
СМЕРТЕЛЬНЫЙ ИСХОД -- FATAL OUTCOME
ФОТОГРАФИЧЕСКИЕ СНИМКИ -- PHOTOGRAPHS
Ключевые слова (''Своб.индексиров.''): прогрессирующая мультифокальная лейкоэнцефалопатия
Аннотация: Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal demyelinating disease of the central nervous system caused by John Cunningham virus (JCV). We present a case report of patient with non-Hodgkin follicular lymphoma, who developed PML after hematopoietic stem cell transplantation and rituximab-bendamustine therapy. JCV DNA was proven both in peripheral blood and cerebrospinal fluid. Patient with 4 years history of follicular lymphoma presented with progressing weakness in the right arm and leg and postural instability. Magnetic resonance imaging scans showed bilateral hyperintense lesions in the cerebellum and centrum semiovale consistent with findings in PML. JCV DNA was detected in patient peripheral blood and cerebrospinal fluid by real time polymerase chain reaction assay in CERBA laboratory (France). Human herpes simplex 6 and 7 DNA were also detected in peripheral blood by PCR. Patients condition rapidly deteriorated with exitus letalis after 3 months and 2 weeks from onset of symptoms. This case draws attention to risk for developing PML in patients with long-standing hematological malignancies
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7.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Lejniece S.
Заглавие : Тромбоцитопения
Место публикации : Внутрішня медицина. - 2009. - № 5/6. - С. 62-68 (Шифр 98926/2009/5/6)
Предметные рубрики: Тромбоцитопения-- диагн-- лек тер-- хир
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8.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Lejniece S.
Заглавие : Гемолітичні анемії
Место публикации : Внутрішня медицина. - 2009. - № 5/6. - С. 58-61 (Шифр 98926/2009/5/6)
Предметные рубрики: Анемия гемолитическая-- диагн-- лек тер
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9.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Auziņa D., Beinaroviča I., Janicka-Kupra B., Lejniece S., Lejnieks A., Groma V.
Заглавие : Dickkopf-related protein 1 expression in bone marrow of multiple myeloma patients: correlation with bone disease and plasma cell malignancy type
Место публикации : Экспериментальная онкология. - 2020. - Т. 42, № 4. - С. 285-288 (Шифр ЕУ12/2020/42/4)
Примечания : Бібліогр.: в кінці ст.
Аннотация: Previous studies have pointed out the role of dickkopf-related protein 1 (DKK 1) — Wnt inhibitor, which is essential for osteoblast functioning, in the development of osteolytic lesions in multiple myeloma (MM). Aim: To assess the DKK 1 expression displayed by myeloma cells in bone marrow trephine biopsies of patients with and without osteolytic lesions, and in different malignancy grades of the disease. Methods: The expression level of DKK 1 was assessed immunohistochemically in bone marrow of 49 MM patients presented with and without osteolytic lesions (the 1st and the 2nd group, respectively). Results: Levels of weak, moderate, and strong DKK 1 expression were distributed — as 43.33, 27.78 and 25.56%, and 63.91, 18.80, and 1.50%, respectively when evaluating the samples obtained from the 1st group and 2nd group. Statistically significant differences were found when the levels of DKK 1 expression in the 1st and the 2nd group were compared (χ2 = 51; df = 3; p 0.001). Conclusions: DKK 1 contributes to the development of osteolytic lesions in MM. The present study provides morphological evidence that inhibition in Wnt signaling may lead to bone damage observed in the advanced stage of the disease
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10.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Auzina D., Erts R., Lejniece S.
Заглавие : Prognostic value of the bone turnover markers in multiple myeloma
Место публикации : Experimental Oncology. - К., 2017. - Том 39, N 1. - С. 53-56: табл. (Шифр ЕУ12/2017/39/1)
Примечания : 25 ref.
MeSH-главная: МИЕЛОМА МНОЖЕСТВЕННАЯ -- MULTIPLE MYELOMA
Аннотация: Multiple myeloma (MM) is characterized by osteolytic bone disease resulting from increased osteoclast activity and reduced osteoblast function. Aim: The aim of our research was to determine connection between bone turnover markers and presence of bone lesions, their degree of severity, to monitor MM bone disease and to assess effectiveness of anti-myeloma treatment. Materials and Methods: Serum samples and clinical data from 123 patients with newly diagnosed MM were collected at Riga East Clinical University Hospital (Riga, Latvia) from June 2014 to June 2016. Bone lesions detected by radiography, CT scans, MRI, and PET/CT were divided into degrees from 0 to 3 (0 — no bone involvement, 1 — ≤ 3 bone lesions, 2 — ≥ 3 bone lesions, 3 — fracture). Staging was performed applying Durie/Salmon (DS) and International Staging System classifications. Progressive disease was defined as development of one or more new bone lesions. The levels of bone metabolic markers β-isomerized C-terminal telopeptide of collagen type I (β-CTX) and bone-specific alkaline phosphatase (bALP) were monitored regularly in the year. Results: Bone lesions were found in 86 (69%) patients. From these 6 (4%) patients had 1st degree, 11 (9%) had 2nd degree and 69 (56%) had 3rd degree bone lesions. Level of the bone resorption marker β-CTX in the control group was 0.41 ng/ml, which is lower than in MM patients (p 0.001). Spearman correlation coefficient analysis found a positive and statistically significant correlation (rs 0.05). However, β-CTX was found to be an excellent diagnostic marker for MM (AUC 0.91; 95% confidence interval, 0.88–0.94; p 0.001). Conclusions: Patients with MM and bone lesions have increased value of bone resorption marker β-CTX. There is a correlation between bone resorption marker and degree of bone lesions. Changes in β-CTX levels may be used to monitor the effectiveness of myeloma treatment
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11.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Gavars D., Perminov D., Tauckels E., Lindenberga I., Auce A., Lejniece S.
Заглавие : Association of elevated vitamin B12 with oncohematological diseases in a cohort of 79, 524 patients from Lanvia
Место публикации : Experimental Oncology. - К., 2019. - Том 41, N 4. - С. 357-362 (Шифр ЕУ12/2019/41/4)
Аннотация: Currently there are some large-scale studies of elevated total vitamin B12 in relation to diseases and their prognosis. Aim of this retrospective study was to determine association of increased B12 as an additional diagnostic marker of oncohematological diseases by a statistical analysis of clinical data of 79,524 patients. Materials and Methods: Overall Latvian population representative data on B12 testing in 79,524 patients were obtained from laboratory database. The following exclusion criteria were applied: fluctuating B12 results within a three-month period, elevated ( 100 U/L) alanine transaminase or aspartate transaminase, hepatitis (HAV, HBV, and HCV) infection, reduced glomerular filtration rate ( 45 mL/min/1.73 m2). As a control group, individuals with normal B12 level and any oncologic diagnosis (solid cancer or hematological malignancies) were selected. Results: After application of step-by-step exclusion filters, 1,373 patients were left with significantly increased level of plasma B12 ( 1,700 pg/mL). Odds ratios for oncohematological diseases in total and myeloid leukemia (including acute, chronic and unspecified) in patient group with elevated B12 were found to be 6.0 (95% CI 4.7–7.6; p 0.0001) and 19.2 (95% CI 13.1–28.0; p 0.0001), respectively, as compared to the control group. Conclusion: Elevated total B12 could be considered as a potential marker for oncohematological disorders
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