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1.

Заглавие журнала :The Ukrainian biochemical journal -2020г. т.92,N 1
Интересные статьи :
Geraschchenko G. V. Pattern of expression of immune- and stroma-associated genes in blood of mice with experimental B16 melanoma/ G. V. Geraschchenko [et al.] (стр.5-11)
Moghadam F. H. Proline dehydrogenase (prodh) gene polymorphisms and the risk of schizophrenia in iranian populations/ F. H. Moghadam [et al.] (стр.12-20)
Veklich T. O. Inhibition of Na(+),K(+)-ATPase and activation of myosin ATPase by CALIX[4]A RENE C-107 cause stimulation of isolated smooth muscle contractile activity/ T. O. Veklich [et al.] (стр.21-30)
Tykhomyrov A. A. Plasminogen modulates formation and release of platelet angiogenic regulators/ A. A. Tykhomyrov, D. D. Zhernosekov, T. V. Grinenko (стр.31-40)
Korotkov S. M. Influence of Tl(+) on the Ca(2+) and Na(+) movement across rat neonatal cardiomyocytes and rat heart mitochondria membranes/ S. M. Korotkov [et al.] (стр.41-55)
Ali F. Profiling of metabolic biomarkers in the serum of prostate cancer patients/ F. Ali [et al.] (стр.56-65)
Fedota O. M. Methotrexate effect on biochemical indices of psoriasis patients depends on MTHFR gene polymorphism/ O. M. Fedota [et al.] (стр.66-74)
Yaremchuk O. Z. Indexes of nitric oxide system in experimental antiphospholipid syndrome/ O. Z. Yaremchuk [et al.] (стр.75-83)
Gudzenko T. V. Phenol-oxidizing activity and fatty acid profile of Brevibacillus centrosporus F14 strain/ T. V. Gudzenko [et al.] (стр.84-91)
Moravej R. Production and physicochemical characterization of xanrhan gum by native lactose consuming isolates of Xanthomonas citri subsp. citri/ R. Moravej [et al.] (стр.92-102)
Sehin T. B. Biochemical indicators of green photosynthetic bacteria Chlorobium limicola response to Cu2+ action/ T. B. Sehin [et al.] (стр.103-112)
Kopylchuk H. P. Indexes of citrulline metabolism in rat liver under the toxic injury against the background of alimentary protein deficiency/ H. P. Kopylchuk, I. M. Nykolaichuk, I. S. Lylyk (стр.113-119)
Polokhina K. V. Cytotoxic activity of the cluster rhenium compound with β-alanine ligands/ K. V. Polokhina [et al.] (стр.120-126)
Ketsa O. V. Free radical oxidation in liver mitochondria of tumor-bearing rats and its correction by essential lipophilic nutrients/ O. V. Ketsa, M. M. Marchenko (стр.127-134)
Виноградова Р. П. Внесок Нобелівських лауреатів в дослідження метаболізму вуглеводів і його регуляцію. А. Гарден, Х. Ейлер-Гельпін, К. Ф. Корі, Г. Т. Корі, Е. Сазерленд, Л. Ф. Лелуар, Г. Кребс, Ф. Ліпман, П. Мітчелл/ Р. П. Виноградова, В. М. Данилова, С. В. Комісаренко (стр.135-163)
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2.

Заглавие журнала :The Ukrainian biochemical journal -2018г. т.90,N 5
Интересные статьи :
Pushkarev V. M. Biochemical aspects of the combined use of taxanes, irradiation and other antineoplastic agents for the treatment of anaplastic thyroid carcinoma/ V. M. Pushkarev [et al.] (стр.5-18)
Borzova N. V. Influence of chemical reagents and UV irradiation on the activity of Penicillium canescens α-galactosidase/ N. V. Borzova, L. D. Varbanets (стр.19-27)
Osadchuk T. V. Influence of organic solvents on the furin activity/ T. V. Osadchuk [et al] (стр.28-33)
Veklich T. O. Calix[4]arene C-956 selectively inhibits plasma membrane Ca2+,Mg2+-ATPase in myometrial cells/ T. O. Veklich [et al.] (стр.34-42)
Afanasieva K. S. DNA loops after cell lysis resemble chromatin loops in an intact nucleus/ K. S. Afanasieva, V. V. Olefirenko, A. V. Sivolob (стр.43-49)
Yastreb T. O. Action of methyl jasmonate and salt stress on antioxidant system of Arabidopsis plants defective in jasmonate signaling genes/ T. O. Yastreb [et al.] (стр.50-59)
Storozhuk B. G. Overall hemostasis potential of the blood plasma and its relation to some molecular markers of the hemostasis system in patients with chronic renal disease of stage VD/ B. G. Storozhuk [et al.] (стр.60-70)
Falfushynska H. I. Evaluation of metallothioneins, oxidative stress and signs of cytotoxicity in young obese women/ H. I. Falfushynska [et al.] (стр.71-80)
Dziuba O. S. The effect of N-stearoylethanolamine on adipocytes free cholesterol content and phospholipid composition in rats with obesity-induced insulin resistance/ O. S. Dziuba [et al.] (стр.81-90)
Krynytska I. Ya. The indices of nitrogen (II) oxide system in experimental hepatopulmonary syndrome/ I. Ya. Krynytska, M. I. Marushchak (стр.91-97)
Gudkova O. O. Purification procedure and assay for the activity of lysyl oxidase/ O. O. Gudkova [et al.] (стр.98-105)
Kosterin S. O. Founder of molecular immunology in Ukraine, well-known political and public figure. On the 75th birthday of Academician of the NAS of Ukraine S. V. Komisarenko/ S. O. Kosterin, V. M. Danilova (стр.106-116)
Matyshevska O. P. The FEBS3+ Meeting - XIth Parnas Conference - Young Scientists Forum ’Biochemistry and Molecular Biology for Innovative Medicine’/ O. P. Matyshevska (стр.117-119)
The Nobel Prize in Physiology or Medicine 2018 (стр.120)
The Nobel Prize in Chemistry 2018 (стр.121)
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3.

Заглавие журнала :The Ukrainian biochemical journal -2018г. т.90,N 4
Интересные статьи :
Veklich T. O. Pathways and mechanisms of transmembrane calcium ions exchange in the cell nucleus/ T. O. Veklich, Yu. V. Nikonishyna, S. O. Kosterin (стр.5-24)
Zaiets I. V. The P60-S6K1 isoform of ribosomal protein S6 kinaze 1 is a product of alternative mRNA translation/ I. V. Zaiets [et al.] (стр.25-35)
Shymanskyi I. O. Liver cytochrome P450-hydroxylation system of tumor-bearing rats under the influence of ?-3 polyunsaturated fatty acids and vitamin D3/ I. O. Shymanskyi [et al.] (стр.36-44)
Ajilore B. S. Gentamicin and magnesium chloride normalizes cholinesterase and ATPase activities in rats acutely exposed to dichlorvos (DDVP) pesticide/ B. S. Ajilore, A. E. Adewuyi, T. O. Oluwadairo (стр.45-51)
Makarchikov A. F. Adenosine thiamine triphosphate and adenosine thiamine triphosphate hydrolase activity in animal tissues/ A. F. Makarchikov [et al.] (стр.52-63)
Kaplia A. A. Assessment of the effect of monohydroxy alcohols, unsaturated fatty acids, organophosphate compounds on the enzymatic ATP-hydrolysis in the cell membranes of the smooth muscle of the rat colon/ A. A. Kaplia, S. V. Midyk, S. V. Khyzhnyak (стр.64-73)
Yukalo V. G. Isolation of к-CN-1P and β-CN-5P fractions from native casein micelles/ V. G. Yukalo, L. A. Storozh (стр.74-79)
Bobrovnik S. A. Effect of trifluoroethanol on antibody reactivity against corresponding and nonrealated antigens/ S. A. Bobrovnik, M. O. Demchenko, S. V. Komisarenko (стр.80-89)
Sierra-Campos E. Nitrate and nitrite in drinking water affect antioxidant enzymes in erythrocytes of rats/ E. Sierra-Campos [et al.] (стр.90-101)
Salyha N. O. Effects of L-glutamic acid and pyridoxine on glutathione depletion and lipid peroxidation generated by epinephrine-induced stress in rats/ N. O. Salyha (стр.102-110)
Asadi A. Evaluation of serum adenosine deainase and its isoenzymes in patients with ovarian cancer/ A. Asadi [et al.] (стр.111-114)
Ozbolat. Hematologic features of beta-globin gene mutation type (??) with homozygous beta thalassemia/ Guluzar Ozbolat, Abdullah Tuli (стр.115-120)
Данилова В. М. Альфред Бернгард Нобель і Нобелівська премія/ В. М. Данилова, Р. П. Виноградова, С. В. Комісаренко (стр.121-134)
Danylova T. V. Scientific investigation of Nobel prize winner Emil Fischer as a launching pad for the development of biochemistry: a brief overview/ T. V. Danylova, S. V. Komisarenko (стр.135-142)
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4.

Заглавие журнала :Український біохімічний журнал -2016г. т.88,N 2
Интересные статьи :
Veklich T. O. The inhibitory influence of calix[4]arene of C-90 on the activity of Ca(2+),Mg(2+)-ATPases in plasma membrane and sarcoplasmic reticulum in myometrium сells/ T. O. Veklich (стр.5-15)
Yatsenko T. A. Effect of fibrin degradation products on fibrinolytic process/ T. A. Yatsenko [и др.] (стр.16-24)
Minchenko O. H. Inhibition of IRE1 modifies the hypoxic regulation of GADD family gene expressions in U87 glioma cells/ O. H. Minchenko [и др.] (стр.25-34)
Ashok Sahu. Cardiovascular disease among patients with type 2 diabetes: role of homocysteine as an inflammatory marker/ Sahu Ashok [и др.] (стр.35-44)
Vovk O. I. Effects of the combined arginase and canavanine treatment on leukemic cells in vitro and in vivo/ O. I. Vovk [и др.] (стр.45-55)
Pyrogova L. V. Level of overall hemostasis potential in donor and patient plasma in pathology/ L. V. Pyrogova [и др.] (стр.56-65)
Kopylchuk G. P. Peculiarities of the free radical processes in rat liver mitochondria under toxic hepatitis on the background of alimentary protein deficiency/ G. P. Kopylchuk, O. M. Voloshchuk (стр.66-72)
Golovenko N. Ya. Physical-chemical properties and the reactivity of pyridoxine and pyrrolidone carboxylate and their protolytic forms/ N. Ya. Golovenko, V. B. Larionov, O. V. Karpova (стр.73-81)
Nozdrenko D. M. The effect of chlorpyrifos upon ATPase activity of sarcoplasmic reticulum and biomechanics of skeletal muscle contraction/ D. M. Nozdrenko [и др.] (стр.82-88)
Kovalenko N. O. Gene expression of H(+)-pumps in plasma and vacuolar membranes of corn root cells under the effect of sodium ions and bioactive preparations/ N. O. Kovalenko, T. A. Palladina (стр.89-97)
Rushchak V. V. Cytochrome P450 2E1 participation in the pathogenesis of experimental metabolic syndrome in guinea pigs/ V. V. Rushchak, M. O. Chashchyn (стр.98-106)
Данилова В. М. Винахідницька діяльність відділу структури і функції білка Інституту біохімії ім. О. В. Палладіна НАН України. Частина І. Розроблення діагностичних методів для виявлення порушень системи гемостазу і характеристика окремих факторів зсідання крові/ В. М. Данилова, Р. П. Виноградова, М. В. Григор’єва (стр.107-118)
Варбанець Л. Д. Рецензія на книгу «Основи глікобіології» (за ред. проф. Н. О. Сибірної)/ Л. Д. Варбанець (стр.119-120)
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5.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Veklich T. O., Labyntseva R. D., Shkrabak O. A., Tsymbalyuk O. V., Rodik R. V., Kalchenko V. I., Kosterin S. O.
Заглавие : Inhibition of Na(+),K(+)-ATPase and activation of myosin ATPase by CALIX[4]A RENE C-107 cause stimulation of isolated smooth muscle contractile activity
Место публикации : The Ukrainian biochemical journal. - Київ, 2020. - Vol. 92, № 1. - С. 21-30 (Шифр УУ60/2020/92/1)
MeSH-главная: МЫШЦЫ -- MUSCLES
Аннотация: The discovery of compounds that might modify myometrial contractility is an important area of researches. In our previous experiments, we found that some representatives of macrocyclic compounds fami­ly – calix[4]arenes – can modify the enzymatic and transport activity of membrane-bound cation-transport ATP hydrolases. The aim of this work was to study and compare the effect of calix[4]arene C-107 on the enzymatic activities of Mg2+-dependent ATPases of the uterine smooth muscle, namely: ouabain-sensitive Na+,K+-ATPase, plasma membrane Ca2+-independent “basal” Mg2+-ATPase, ATPase of the actomyosin complex and myosin subfragment-1, with effect on the contractile activity of the myometrium. It was shown that calix[4]arene C-107 efficiently inhibited myometrium Na+,K+-ATPase (I50 = 54 ± 6 nM) selectively to other ATP-hydrolases of the plasma membrane and simultaneously activated the enzymatic activity of the myosin ATPase of smooth muscles (A50 = 9.6 ± 0.7 μM). Such reciprocal biochemical effects led to the stimulation of the smooth muscle contractile activity that was demonstrated by the tensometric method using different isolated smooth muscles. Calix[4]arene С-107 was shown to stimulate the increase of the tonic component of myometrium contractions induced by oxytocin, as well as contractions of the caecum muscles induced by high-potassium solution or acetylcholine, and to maintain increased tension for a long time. Thus, calix[4]arene C-107 is a prospective compound for enhancing the smooth muscle basal tone and/or contraction in case of hypotonic dysfunctions
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6.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Veklich T. O., Skrabak O. A., Nikonishyna Yu. V., Rodik R. V., Kalchenko V. I., Kosterin S. O.
Заглавие : Calix[4]arene C-956 selectively inhibits plasma membrane Ca2+,Mg2+-ATPase in myometrial cells
Место публикации : The Ukrainian Biochemical Journal. - Київ, 2018. - Том 90, N 5. - С. 34-42 (Шифр УУ60/2018/90/5)
MeSH-главная: МИОМЕТРИЙ -- MYOMETRIUM
Аннотация: Using enzymatic assays and kinetic analysis, we demonstrated that 100 µM calix[4]arene C-956 (5,11,17,23-tetra(trifluoro)methyl-(phenylsulfonylimino) methylamino-25,27-dioctyloxy-26,28-dipropoxycalix[4]arene) had the most significant inhibitory effect on the plasma membrane Са2+,Mg2+-АТРase activity compared to effects of other calix[4]arenes, and had no effect on specific activities of other membrane ATPases. Using confocal microscopy and fluorescent probe fluo-4, we observed an increase of the intracellular level of Ca2+ after application of calix[4]arene C-956 to immobilized myocytes. Analysis of the effect of calix[4]arene C-956 on the hydrodynamic diameter of myocytes demonstrated that application of calix[4]arene C-956 solution decreased this parameter by 45.5 ± 9.4% compared to control value similarly to the action of uterotonic drug oxytocin
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7.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Veklich T. O.
Заглавие : The inhibitory influence of calix[4]arene of C-90 on the activity of Ca(2+),Mg(2+)-ATPases in plasma membrane and sarcoplasmic reticulum in myometrium сells
Параллельн. заглавия :Інгібіторний вплив калікс[4]арену С-90 на ензиматичну активність транспортних Са(2+),Mg(2+)-АТРаз плазматичної мембрани та саркоплазматичного ретикулума міометрія
Место публикации : Український біохімічний журнал. - 2016. - Т. 88, № 2. - С. 5-15 (Шифр УУ1/2016/88/2)
Примечания : Bibliogr. at the end of the art
MeSH-главная: КЛЕТОЧНАЯ МЕМБРАНА -- CELL MEMBRANE
КАЛЬЦИЙ-ТРАНСПОРТИРУЮЩИЕ АТФАЗЫ ПЛАЗМАТИЧЕСКИХ МЕМБРАН -- PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES
АТФАЗА-CA(2+) MG(2+) -- CA(2+) MG(2+)-ATPASE
САРКОПЛАЗМАТИЧЕСКИЙ РЕТИКУЛУМ -- SARCOPLASMIC RETICULUM
МИОМЕТРИЙ -- MYOMETRIUM
КАЛИКСАРЕНЫ -- CALIXARENES
БИОХИМИЧЕСКИЕ ПРОЦЕССЫ -- BIOCHEMICAL PROCESSES
ГИДРОЛИЗ -- HYDROLYSIS
Аннотация: Our study on the plasma membrane vesicles and myometrium cells treated with 0.1% digitonin showed that inhibitory effect of calix[4]arene C-90 (5,11,17,23-tetra(trifluoro)methyl(phenylsulphonylimino)-methylamino-25,26,27,28-tetrapropoxy-calix[4]arene) on the plasma membrane Ca2+,Mg2+-ATPase was more significant than on the Ca2+,Mg2+-ATPase in sarcoplasmic reticulum (the inhibition coefficient I0.5 values were 20.2 ± 0.5 µM and 57.0 ± 1.4 µM for the plasma membrane Ca2+,Mg2+-ATPase and Ca2+,Mg2+-ATPase in sarcoplasmic reticulum, respectively (n = 5)). Inhibition kinetics of calix[4]arene C-90 effect on the Ca2+,Mg2+-ATPase activities in plasma membrane and sarcoplasmic reticulum were studied. This substance inhibited both pumps as complete noncompetitive inhibitor. Calix[4]arene C-90 caused the increase of intracellular Ca2+ concentration and decrease of hydrodynamic diameter in smooth muscle cells similar to the action of uterotonic drug oxytocin
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8.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Veklich T. O., Nikonishyna Yu. V., Kosterin S. O.
Заглавие : Pathways and mechanisms of transmembrane calcium ions exchange in the cell nucleus
Место публикации : The Ukrainian Biochemical Journal. - Київ, 2018. - Том 90, N 4. - С. 5-24 (Шифр УУ60/2018/90/4)
MeSH-главная: КЛЕТКИ ЯДРО -- CELL NUCLEUS
КАЛЬЦИЙ -- CALCIUM
НУКЛЕОПЛАЗМИНЫ -- NUCLEOPLASMINS
Аннотация: A variety of nuclear calcium functions includes regulations of gene transcription and permeability of nuclear pore complexes, activation of numerous enzymes involved in the apoptosis, and therefore cell fate determination. Thus, the pathways of Ca2+ entry into the nucleus, the interplay between nuclear and cytosolic calcium signals, calcium accumulation in the nuclear depot, extrusion and subsequent destinies are of particular interest. In this review, we systematized literature data and our results about aspects of calcium transport in the cell. We especially concentrated on calcium transport systems and general mechanisms of calcium exchange in the central organelle – the nucleus. We also described the general structure of the cell nucleus, nuclear envelope transporters, and the role of Ca2+ in the nucleus and disturbances of nuclear calcium signaling
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